Results 271 to 280 of about 320,405 (317)

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

OSBPL3 promotes colorectal cancer progression through modulation of TGF-β signaling and immune cell infiltration. [PDF]

Transl Cancer Res
Liang W, Wang C, Wei J, Zhou C, He C, He Y, Zhao J, Li S, Cao J.   +8 more
europepmc   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

TGF-β-induced fibrotic scar formation limits recovery of spinal cord injury. [PDF]

Bone Res
Pan D, Wu P, Noller K, Cahan P, Cao X.
europepmc   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

TGF-β Inhibitor Potentiates Osimertinib-Induced Anti-Tumor Immunity in Egfr-Mutant Lung Cancer. [PDF]

Cancer Sci
Kuribayashi T, Nishimura J, Okawa S, Taoka M, Mori S, Tanaka T, Nishimura T, Morita A, Hara N, Ninomiya K, Makimoto G, Rai K, Ichihara E, Hotta K, Togashi Y, Maeda Y, Kiura K, Ohashi K.   +17 more
europepmc   +1 more source

HUMAN-E: Hypothesis on TGF-β Reduction for Muscle Growth, Immunity, and Healing

Archit Vajpayee
openalex   +1 more source

MFAP2 Promotes Epithelial-Mesenchymal Transition in Gastric Cancer Cells by Activating TGF-β/SMAD2/3 Signaling Pathway [Retraction]. [PDF]

Onco Targets Ther
europepmc   +1 more source

TGF-β Blockade With SB525334 Enhances B7-H3 CAR-γδT Cell Efficacy Against Glioblastoma. [PDF]

J Cell Mol Med
Zhu Y, Han Z, Zhou Z, Sui Y, Zhang Y, Jiang Z, E Q, Zhang X, Wang W, Hou Y, Du J, Tang Y, Dong H, Xu Y, Sun R, Li C, Li X, Huang Y.   +17 more
europepmc   +1 more source

The interplay between TGF-β and VEGF signalling in endothelial cell function

, 2014
Zhen Liu
openalex   +1 more source