Results 11 to 20 of about 166,365 (294)
THU0004 MICRORNA-223 NEGATIVELY REGULATE GOUTY INFLAMMATION BY TARGETING THE NLRP3 INFLAMMASOME WITHOUT INFLUENCING IL-37 AND TGF-î'1 [PDF]
Annals of the Rheumatic Diseases, 2019 Background MicroRNA-223 (miR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders[1]. To date, no relevant studies have reported the expression levels of miR-223 in gout patients or assessed whether miR-223 participates in negatively regulating gouty inflammation via ...
Yu-Feng Qing +5 more
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Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers [PDF]
, 2014 [Image: see text] TGF-β1, -β2, and -β3 are small, secreted signaling proteins. They share 71–80% sequence identity and signal through the same receptors, yet the isoform-specific null mice have distinctive phenotypes and are inviable.
Andrew P. Hinck +61 more
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Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells [PDF]
, 2013 Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexin-mediated intercellular communication in proximal tubule-derived epithelial cells.
Hills, Claire E. +3 more
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Molecular Therapy: Nucleic Acids, 2017 Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for ...
Jung-Yeon Kim +6 more
doaj +1 more source
Biology, 2020 Transforming growth factor-β1 (TGF-β1) is highly expressed in the tumor microenvironment and known to play a multifunctional role in cancer progression.
Ji-Hoon Jeong +9 more
doaj +1 more source
The Egyptian Heart Journal, 2021 Background Coronary artery ectasia (CAE) is described as the enlargement of a coronary artery segment by 1.5 times or more, which is generally associated with the atherosclerotic process. Atherosclerotic changes lead to arterial remodeling result in CAE.
Özgür Selim Ser +10 more
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EGF and TGF-β1 effects on thyroid function [PDF]
, 2011 Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF-β receptors, as
Gabriella Mincione +7 more
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KADAR TGF-β1 PLASMA DAN LIMFOSIT-T CD4+DI PENDERITA YANG TERINFEKSI HIV STADIUM I
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018 HIV infection and AIDS have been spread throughout the world and the number of patients continues to increase from year to year.Indonesia is one of the countries with quite a high increase in the incidence of HIV and AIDS. The absolute number of CD4+T-lymphocytesand percentage in HIV-infected patients can be used to determine the stage of the disease ...
Albertina +2 more
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Nanoparticle-mediated local delivery of an antisense TGF-β1 construct inhibits intimal hyperplasia in autogenous vein grafts in rats. [PDF]
PLoS ONE, 2012 Intimal hyperplasia is one of the most important causes of vascular graft failure. Numerous studies have correlated transforming growth factor-β1 (TGF-β1) with extracellular matrix (ECM) deposition, a hallmark of intimal thickening.In the present study ...
Da-Xin Sun +5 more
doaj +1 more source
Molecular Biology & Nanomedicine, 2021 Nasopharyngeal carcinoma(NPC)is the most common canceroriginating in the nasopharynx with high incidence of nasopharyngeal carcinoma. This study aimsto identify possible prognostic factors of related proteins in the TGF-β/Smadsignaling pathway in NPC.The
Yanwei Rao +3 more
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