Results 11 to 20 of about 113,485 (253)
Hubungan Kadar TGF-β1 dan IFN-ɣ dengan Indeks Kronisitas Nefritis Lupus
Jurnal Kedokteran Brawijaya, 2013 Meskipun perbaikan penatalaksanaan terapi telah dilakukan dalam dua dekade terakhir , tetapi prognosis nefritis lupus tetap  tidak  memuaskan.  Oleh  karena  itu  diperlukan  suatu  biomarker  yang  dapat  menggambarkan  aktivitas  penyakit. Penelitian ini  dilakukan untuk untuk melihat peran TGF-β1 urin dan IFN-ɣ  urin sebagai ...
Indah Jayani +2 more
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Bioscience Journal, 2018 Mesenchymal stem cells (MSC) are multipotent cells derived from layer mesoderm and that have potential for self-renewal and cellular differentiation. These cells can be extracted from various tissues, being the main sources the bone marrow (BM) and adipose tissue (AT).
Vivian Alonso Goulart +5 more
openaire +4 more sources
Molecular Therapy: Nucleic Acids, 2017 Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for ...
Jung-Yeon Kim +6 more
doaj +1 more source
KADAR TGF-β1 PLASMA DAN LIMFOSIT-T CD4+DI PENDERITA YANG TERINFEKSI HIV STADIUM I
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018 HIV infection and AIDS have been spread throughout the world and the number of patients continues to increase from year to year.Indonesia is one of the countries with quite a high increase in the incidence of HIV and AIDS. The absolute number of CD4+T-lymphocytesand percentage in HIV-infected patients can be used to determine the stage of the disease ...
Albertina +2 more
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Biology, 2020 Transforming growth factor-β1 (TGF-β1) is highly expressed in the tumor microenvironment and known to play a multifunctional role in cancer progression.
Ji-Hoon Jeong +9 more
doaj +1 more source
Open Life Sciences, 2021 Transforming growth factor (TGF)-β1 and mesenchymal stromal cells (MSCs) are two effective immunosuppressive agents for organ transplantation technology.
Li Ruixue +6 more
doaj +1 more source
miR-363 Alleviates Detrusor Fibrosis via the TGF-β1/Smad Signaling Pathway by Targeting Col1a2 in Rat Models of STZ-Induced T2DM [PDF]
Molecular Therapy - Nucleic Acids, 2020 Dysregulated expression of microRNAs (miRNAs or miRs) has been implicated in the pathophysiology of type 2 diabetes mellitus (T2DM). However, their underlying role in the complication of detrusor fibrosis remains poorly understood. Therefore, this study aimed to examine the potential functional relevance of miR-363 in detrusor fibrosis of rats with ...
Xue-Feng Li +3 more
openaire +5 more sources
Cell Transplantation, 2002 Nonobese diabetic (NOD) mice develop diabetes and destroy syngeneic islet grafts through an autoimmune response. Because transforming growth factor (TGF)-β1 downregulates immune responses, we tested whether overexpression of TGF-β1 by gene transfection ...
Wilma L. Suarez-Pinzon +3 more
doaj +1 more source
Nanoparticle-mediated local delivery of an antisense TGF-β1 construct inhibits intimal hyperplasia in autogenous vein grafts in rats. [PDF]
PLoS ONE, 2012 Intimal hyperplasia is one of the most important causes of vascular graft failure. Numerous studies have correlated transforming growth factor-β1 (TGF-β1) with extracellular matrix (ECM) deposition, a hallmark of intimal thickening.In the present study ...
Da-Xin Sun +5 more
doaj +1 more source
International Journal of Endocrinology, 2019 Objective. To investigate the role of microRNA-130b in 1,25(OH)2D3 mediated improvement of renal fibrosis via transforming growth factor-beta 1 in a rat model of diabetic nephropathy (DN). Methods.
Yuetong Liu +10 more
doaj +1 more source