Results 41 to 50 of about 166,365 (294)
PLoS ONE, 2022 Orthodontic treatment requires the regulation of bone remodeling in both compression and tension sides. Transforming growth factor-β1 (TGF-β1) is an important coupling factor for bone remodeling.
Momoko Inoue +5 more
doaj +3 more sources
JCI Insight, 2023 Pulmonary fibrosis is potentiated by a positive feedback loop involving the extracellular sialidase enzyme neuraminidase 3 (NEU3) causing release of active TGF-β1 and TGF-β1 upregulating NEU3 by increasing translation without affecting mRNA levels.
Wensheng Chen +2 more
doaj +1 more source
TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors [PDF]
, 2004 Background The adenine nucleotide translocator 1 (Ant1) is an inner mitochondrial membrane protein involved with energy mobilization during oxidative phosphorylation.
Wallace Douglas C +5 more
core +2 more sources
CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung [PDF]
Frontiers in Pharmacology, 2014 Pulmonary fibrosis is a difficult to treat, often fatal disease whose pathogenesis involves dysregulated TGF-β1 signaling. CD4+CD25+FoxP3+ Regulatory T cells ("Tregs") exert important effects on host tolerance and arise from naïve CD4+ lymphocytes in response to TGF-β1.
Peng, Xueyan +6 more
openaire +3 more sources
Sialylation of vasorin by ST3Gal1 facilitates TGF-β1-mediated tumor angiogenesis and progression. [PDF]
, 2019 ST3Gal1 is a key sialyltransferase which adds α2,3-linked sialic acid to substrates and generates core 1 O-glycan structure. Upregulation of ST3Gal1 has been associated with worse prognosis of breast cancer patients.
Chang, Margaret Dah-Tsyr +15 more
core +2 more sources
Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo [PDF]
, 2014 Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease of insidious onset, and is responsible for up to 30,000 deaths per year in the U.S.
Lasky, Joseph A +6 more
core +5 more sources
Mediators of Inflammation, 1995 We investigated the effect of transforming factor factor-β1 (TGF-β1) on thromboxane B2 (TXB2) and prostaglandin E2 (PGE2) production in in vitro silica dust-exposed rat alveolar macrophages (AM).
Urszula Orlinska, Douglas C. Kuhn
doaj +1 more source
Preparation and functional identification of anti-human transforming growth factor β1 nanobodies [PDF]
Jichu yixue yu linchuang, 2020 Objective To prepare alpaca-derived anti-human TGF-β1 nanobodies with high specificity and high affinity. Methods The eukaryotic expression plasmid cFUGW-TGF-β1 was constructed and transiently transfected into HEK-293T cells to obtain recombinant TGF-β1 ...
WANG Yue, LI Zheng, CHEN Hui, ZHANG Jian-min, HE Wei
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Injectable agents for the induction of Peyronie’s disease in model rats: a comparative study
Asian Journal of AndrologyPeyronie’s disease (PD) is a disorder characterized by fibrous plaque formation in the penile tissue that leads to curvature and complications in advanced stages.
Guang-Jun Du +7 more
doaj +1 more source