Results 21 to 30 of about 113,485 (253)

Role of TGF-β/Smad Signaling Pathway-Related Proteins in Clinicopathological Features and Prognosis and Survival of Patients with Nasopharyngeal Carcinoma

open access: yesMolecular Biology & Nanomedicine, 2021
Nasopharyngeal carcinoma(NPC)is the most common canceroriginating in the nasopharynx with high incidence of nasopharyngeal carcinoma. This study aimsto identify possible prognostic factors of related proteins in the TGF-β/Smadsignaling pathway in NPC.The
Yanwei Rao   +3 more
doaj   +1 more source

Transforming growth factor-β1 and -β2 in gastric precancer and cancer and roles in tumor-cell interactions with peripheral blood mononuclear cells in vitro. [PDF]

open access: yesPLoS ONE, 2013
Transforming growth factor-β1 (TGF-β1) and -β2 are correlated with poorer prognosis in gastric cancer (GC), which act in both tumor and immune cells. However, their expressions in precancer and tumor-cell interactions with peripheral blood mononuclear ...
Gui-Fen Ma   +8 more
doaj   +1 more source

TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway

open access: yesReproductive Biology and Endocrinology, 2022
Background Tightly regulation of extravillous cytotrophoblast (EVT) cell invasion is critical for the placentation and establishment of a successful pregnancy.
Lanlan Fang   +7 more
doaj   +1 more source

Hubungan Kadar Transforming Growth Factor-Beta 1 (TGF-β1) Urin dengan Proteinuria pada Anak Sindrom Nefrotik Resisten Steroid

open access: yesJurnal Kedokteran Brawijaya, 2013
 Transforming  Growth  Factor-Beta  1  (TGF-β1)  menjadi  perantara  fibrosis  interstisial,  atrofi  tubular,  dan  kerusakan gromelurus ginjal. Proteinuria menunjukkan prognosis yang buruk pada  sindroma nefrotik. Terdapat kecenderungan persisten proteinuria pada sindroma nefrotik resisten steroid.
Prasetya Ismail P   +2 more
openaire   +2 more sources

Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

open access: yesMediators of Inflammation, 2015
Transforming growth factor (TGF-β1) is among the strongest factors of liver fibrogenesis, but its association with Schistosoma-caused liver fibrosis is controversial. Tissue transglutaminase (tTG) is the principal enzyme controlling TGF-β1 maturation and
Juanjuan Tang   +10 more
doaj   +1 more source

Aberrant activation of TGF-β1 induces high bone turnover via Rho GTPases-mediated cytoskeletal remodeling in Camurati-Engelmann disease

open access: yesFrontiers in Endocrinology, 2022
In the adult skeleton, the bone remodeling process involves a dynamic coordination between osteoblasts and osteoclasts, which is disrupted in diseases with high bone turnover rates and dysregulated transforming growth factor beta 1 (TGF-β1).
Qi Chen   +19 more
doaj   +1 more source

Mechanisms involved in suppression of osteoclast supportive activity by transforming growth factor-β1 via the ubiquitin-proteasome system

open access: yesPLoS ONE, 2022
Orthodontic treatment requires the regulation of bone remodeling in both compression and tension sides. Transforming growth factor-β1 (TGF-β1) is an important coupling factor for bone remodeling.
Momoko Inoue   +5 more
doaj   +3 more sources

TGF-β1 promotes cerebral cortex radial glia-astrocyte differentiation in vivo [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2014
The major neural stem cell population in the developing cerebral cortex is composed of the radial glial cells, which generate glial cells and neurons. The mechanisms that modulate the maintenance of the radial glia (RG) stem cell phenotype, or its differentiation, are not yet completely understood.
Stipursky, Joice   +6 more
openaire   +4 more sources

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. [PDF]

open access: yesPLoS ONE, 2010
Transforming growth factor beta 1 (TGF-β1) is an inhibitor of muscle cell differentiation that is associated with fibrosis, poor regeneration and poor function in some diseases of muscle.
Chateen Krueger, F Michael Hoffmann
doaj   +1 more source

Additional file 1: of Computational analysis reveals the coupling between bistability and the sign of a feedback loop in a TGF-β1 activation model

open access: yes, 2017
Supplementary Notes. (PDF 107 kb)
Li, Huipeng   +5 more
openaire   +1 more source

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