Results 21 to 30 of about 239,501 (262)

Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats

open access: yesInternational Journal of Endocrinology, 2019
Objective. To investigate the role of microRNA-130b in 1,25(OH)2D3 mediated improvement of renal fibrosis via transforming growth factor-beta 1 in a rat model of diabetic nephropathy (DN). Methods.
Yuetong Liu   +10 more
doaj   +1 more source

Transforming growth factor-β1 and -β2 in gastric precancer and cancer and roles in tumor-cell interactions with peripheral blood mononuclear cells in vitro. [PDF]

open access: yesPLoS ONE, 2013
Transforming growth factor-β1 (TGF-β1) and -β2 are correlated with poorer prognosis in gastric cancer (GC), which act in both tumor and immune cells. However, their expressions in precancer and tumor-cell interactions with peripheral blood mononuclear ...
Gui-Fen Ma   +8 more
doaj   +1 more source

Role of TGF-β/Smad Signaling Pathway-Related Proteins in Clinicopathological Features and Prognosis and Survival of Patients with Nasopharyngeal Carcinoma

open access: yesMolecular Biology & Nanomedicine, 2021
Nasopharyngeal carcinoma(NPC)is the most common canceroriginating in the nasopharynx with high incidence of nasopharyngeal carcinoma. This study aimsto identify possible prognostic factors of related proteins in the TGF-β/Smadsignaling pathway in NPC.The
Yanwei Rao   +3 more
doaj   +1 more source

TGF-β1 +29C/T variant as predicted by SIFT, CADD, REVEL, PolyPhen and MetaLR tools.

open access: yes, 2022
TGF-β1 +29C/T variant as predicted by SIFT, CADD, REVEL, PolyPhen and MetaLR tools.
Yasmin Badshah (6894317)   +6 more
core   +1 more source

TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway

open access: yesReproductive Biology and Endocrinology, 2022
Background Tightly regulation of extravillous cytotrophoblast (EVT) cell invasion is critical for the placentation and establishment of a successful pregnancy.
Lanlan Fang   +7 more
doaj   +1 more source

The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy [PDF]

open access: yes, 2011
Transforming Growth Factor-beta (TGF-β) is a pro-sclerotic cytokine widely associated with the development of fibrosis in diabetic nephropathy. Central to the underlying pathology of tubulointerstitial fibrosis is epithelial-to-mesenchymal transition ...
Hills, Claire E.   +3 more
core   +1 more source

Functional cell phenotype induction with TGF-β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair. [PDF]

open access: yes, 2020
Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need.
Zhou, G   +27 more
core   +2 more sources

Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

open access: yesMediators of Inflammation, 2015
Transforming growth factor (TGF-β1) is among the strongest factors of liver fibrogenesis, but its association with Schistosoma-caused liver fibrosis is controversial. Tissue transglutaminase (tTG) is the principal enzyme controlling TGF-β1 maturation and
Juanjuan Tang   +10 more
doaj   +1 more source

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. [PDF]

open access: yesPLoS ONE, 2010
Transforming growth factor beta 1 (TGF-β1) is an inhibitor of muscle cell differentiation that is associated with fibrosis, poor regeneration and poor function in some diseases of muscle.
Chateen Krueger, F Michael Hoffmann
doaj   +1 more source

TGF-β1 suppresses mRNA expression of Nrf2 in HSCs.

open access: yes, 2018
(A) hTERT-HSCs were exposed to 1–5 ng/mL TGF-β1 for 48 hours. mRNA was extracted using TRIzol conventional procedure and fold changes were calculated as 2^(-ΔΔCT) for each sample and control and expressed as mean fold change ± SD (N = 3).
Laura Suter-Dick (4217362)   +1 more
core   +1 more source

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