Results 31 to 40 of about 239,501 (262)
Frontiers in Endocrinology, 2022 In the adult skeleton, the bone remodeling process involves a dynamic coordination between osteoblasts and osteoclasts, which is disrupted in diseases with high bone turnover rates and dysregulated transforming growth factor beta 1 (TGF-β1).
Qi Chen +19 more
doaj +1 more source
TGF-β1 dose response with α-SMA and Collagen I expression in primary human HSCs.
, 2019 HSCs were treated for 48 hours with 9–0.001 ng/ml change to lowest to highest TGF-β1 and then fixed and stained for α-SMA and Collagen I. Percent value is based on maximal response from addition of TGF-β1.
Franklin Schlerman (2381617) +9 more
core +1 more source
PLoS ONE, 2022 Orthodontic treatment requires the regulation of bone remodeling in both compression and tension sides. Transforming growth factor-β1 (TGF-β1) is an important coupling factor for bone remodeling.
Momoko Inoue +5 more
doaj +3 more sources
TGF-β1, -β2 and -β3 inhibit the proliferation of LECs.
, 2016 Primary human LECs were incubated with different concentrations of recombinant TGF-β1, -β2 or -β3 or were left untreated and served as control. Proliferation was assessed using 3H thymidine incorporation assays.
Frederik Wenz (23561) +7 more
core +1 more source
JCI Insight, 2023 Pulmonary fibrosis is potentiated by a positive feedback loop involving the extracellular sialidase enzyme neuraminidase 3 (NEU3) causing release of active TGF-β1 and TGF-β1 upregulating NEU3 by increasing translation without affecting mRNA levels.
Wensheng Chen +2 more
doaj +1 more source
Preparation and functional identification of anti-human transforming growth factor β1 nanobodies [PDF]
Jichu yixue yu linchuang, 2020 Objective To prepare alpaca-derived anti-human TGF-β1 nanobodies with high specificity and high affinity. Methods The eukaryotic expression plasmid cFUGW-TGF-β1 was constructed and transiently transfected into HEK-293T cells to obtain recombinant TGF-β1 ...
WANG Yue, LI Zheng, CHEN Hui, ZHANG Jian-min, HE Wei
doaj
TGF-β1 polymorphism in American tegumentary leishmaniasis in a Southern Brazilian population
, 2019 INTRODUCTION: Genetic polymorphisms define the cytokine production leading to susceptibility or resistance to diseases. We studied the cytokine polymorphism in the development of tegumentary leishmaniasis (TL). METHODS: Genotyping of TNF-α, TGF-β1, IFN-
Sandra Mara Alessi Aristides (405762) +8 more
core +1 more source
TGF-β1 and β3 inhibit phosphorylation of Syk.
, 2017 (a) B cells were cultured overnight without TGF-β or with TGF-β, and BCR stimulation was induced for 3 minutes. Results are representative of three similar experiments. (b) B cells were treated overnight with medium, TGF-β1, or TGF-β3 and stimulated with
Keishi Fujio (24320) +12 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Injectable agents for the induction of Peyronie’s disease in model rats: a comparative study
Asian Journal of AndrologyPeyronie’s disease (PD) is a disorder characterized by fibrous plaque formation in the penile tissue that leads to curvature and complications in advanced stages.
Guang-Jun Du +7 more
doaj +1 more source