Results 31 to 40 of about 166,365 (294)

BMP2 and TGF-β Cooperate Differently during Synovial-Derived Stem-Cell Chondrogenesis in a Dexamethasone-Dependent Manner [PDF]

, 2019
Recent studies highlighting mesenchymal stem cell (MSC) epigenetic memory suggest that a different differentiation medium may be required depending on the tissue of origin.
Alini, Mauro, Basoli, Valentina, Della Bella, Elena, Kovermann, Nikolas J., Kubosch, Eva Johanna, Lischer, Christoph, Schmal, Hagen, Stoddart, Martin J.   +7 more
core   +1 more source

Hubungan Kadar Transforming Growth Factor-Beta 1 (TGF-β1) Urin dengan Proteinuria pada Anak Sindrom Nefrotik Resisten Steroid

Jurnal Kedokteran Brawijaya, 2013
 Transforming  Growth  Factor-Beta  1  (TGF-β1)  menjadi  perantara  fibrosis  interstisial,  atrofi  tubular,  dan  kerusakan gromelurus ginjal. Proteinuria menunjukkan prognosis yang buruk pada  sindroma nefrotik. Terdapat kecenderungan persisten proteinuria pada sindroma nefrotik resisten steroid.
Prasetya Ismail P, L Enggar Fitri, Krisni Subandijah   +2 more
openaire   +2 more sources

TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway

Reproductive Biology and Endocrinology, 2022
Background Tightly regulation of extravillous cytotrophoblast (EVT) cell invasion is critical for the placentation and establishment of a successful pregnancy.
Lanlan Fang, Yang Yan, Yibo Gao, Ze Wu, Zhen Wang, Sizhu Yang, Jung-Chien Cheng, Ying-Pu Sun   +7 more
doaj   +1 more source

Possible Consequences for TGF-β1 Signaling [PDF]

, 2017
Glycosaminoglycans are known to bind biological mediators thereby modulating their biological activity. Sulfated hyaluronans (sHA) were reported to strongly interact with transforming growth factor (TGF)-β1 leading to impaired bioactivity in ...
Koehler, Linda, Köhling, Sebastian, Moeller, Stephanie, Rademann, Jörg, Rother, Sandra, Samsonov, Sergey, Vogel, Sarah   +6 more
core   +1 more source

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage [PDF]

, 2016
Intracerebral hemorrhage (ICH) is a devastating form of stroke that results from the rupture of a blood vessel in the brain, leading to a mass of blood within the brain parenchyma.
Arthur F. Steinschneider, Brian Mac Grory, Brittany A. Goods, Butovsky, Chapman, Che-Feng Chang, Cherry, Corona, David A. Hafler, Devarajan, Dey, Ginhoux, Gomez Perdiguero, Gong, Hua, J. Christopher Love, Lauren H. Sansing, Louise D. McCullough, Manno, Matthew D. Hammond, Michael H. Askenase, Michael T. Mullen, Rankin, Roslyn A. Taylor, Sansing, Scott E. Kasner, Stephen C. Renfroe, Thal, Youxi Ai   +28 more
core   +1 more source

TGF-β1 promotes cerebral cortex radial glia-astrocyte differentiation in vivo [PDF]

Frontiers in Cellular Neuroscience, 2014
The major neural stem cell population in the developing cerebral cortex is composed of the radial glial cells, which generate glial cells and neurons. The mechanisms that modulate the maintenance of the radial glia (RG) stem cell phenotype, or its differentiation, are not yet completely understood.
Stipursky, Joice, Francis, Daniel, Dezonne, Rômulo Sperduto, Bérgamo de Araújo, Ana Paula, Souza, Lays, Moraes, Carolina A., Alcantara Gomes, Flávia Carvalho   +6 more
openaire   +4 more sources

Aberrant activation of TGF-β1 induces high bone turnover via Rho GTPases-mediated cytoskeletal remodeling in Camurati-Engelmann disease

Frontiers in Endocrinology, 2022
In the adult skeleton, the bone remodeling process involves a dynamic coordination between osteoblasts and osteoclasts, which is disrupted in diseases with high bone turnover rates and dysregulated transforming growth factor beta 1 (TGF-β1).
Qi Chen, Qi Chen, Yan Yao, Yan Yao, Kun Chen, Xihui Chen, Xihui Chen, Bowen Li, Bowen Li, Rui Li, Rui Li, Lidangzhi Mo, Lidangzhi Mo, Weihong Hu, Mengjie Zhang, Zhen Wang, Yaoping Wu, Yuanming Wu, Yuanming Wu, Fangfang Liu   +19 more
doaj   +1 more source

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. [PDF]

PLoS ONE, 2010
Transforming growth factor beta 1 (TGF-β1) is an inhibitor of muscle cell differentiation that is associated with fibrosis, poor regeneration and poor function in some diseases of muscle.
Chateen Krueger, F Michael Hoffmann
doaj   +1 more source

Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

Mediators of Inflammation, 2015
Transforming growth factor (TGF-β1) is among the strongest factors of liver fibrogenesis, but its association with Schistosoma-caused liver fibrosis is controversial. Tissue transglutaminase (tTG) is the principal enzyme controlling TGF-β1 maturation and
Juanjuan Tang, Xunmin Zhu, Jingjing Zhao, Mingchiu Fung, Yinyan Li, Zhiyan Gao, Suikai Yan, Xiaomin Li, Xiaofang Ji, Fang Su, Zi Li   +10 more
doaj   +1 more source

TGF-β1-Induced Epithelial–Mesenchymal Transition Promotes Monocyte/Macrophage Properties in Breast Cancer Cells [PDF]

Frontiers in Oncology, 2015
Breast cancer progression toward metastatic disease is linked to re-activation of epithelial-mesenchymal transition (EMT), a latent developmental process. Breast cancer cells undergoing EMT lose epithelial characteristics and gain the capacity to invade the surrounding tissue and migrate away from the primary tumor.
Johansson J, Tabor V, Wikell A, Jalkanen S, Fuxe J   +4 more
openaire   +6 more sources