Results 11 to 20 of about 1,017,685 (306)

Is telomerase reactivation associated with the down-regulation of TGF β receptor-II expression in human breast cancer? [PDF]

Cancer Cell International, 2003
Background Telomerase is a ribonucleoprotein that synthesizes telomeres and plays an important role in chromosomal stability and cellular immortalisation. Telomerase activity is detectable in most human cancers but not in normal somatic cells.
Thomas Valene, Newbold Robert F, Elkak Abd E, Mokbel Kefah   +3 more
doaj   +2 more sources

Role of TGF-β on cardiac structural and electrical remodeling

Vascular Health and Risk Management, 2008
Roberto Ramos-Mondragón, Carlos A Galindo, Guillermo AvilaDepartamento de Bioquímica, Cinvestav-IPN, MéxicoAbstract: The type β transforming growth factors (TGF-βs) are involved in a number of human diseases, including ...
Roberto Ramos-Mondragón, Carlos A Galindo, Guillermo Avila   +2 more
doaj   +1 more source

Using the interplay of magnetic guidance and controlled TGF-β release from protein-based nanocapsules to stimulate chondrogenesis

International Journal of Nanomedicine, 2018
Chih-Sheng Chiang,1 Jian-Yi Chen,1 Min-Yu Chiang,1 Kai-Ting Hou,1 Wei-Ming Li,1 Shwu-Jen Chang,2 San-Yuan Chen11Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan; 2Department of Biomedical Engineering, I ...
Chiang CS, Chen JY, Chiang MY, Hou KT, Li WM, Chang SJ, Chen SY   +6 more
doaj   +1 more source

Urinary TGF-β1 was not independently associated with renal function in diabetes mellitus

Diabetes, Metabolic Syndrome and Obesity, 2018
Rani Sauriasari, Mia Yuliana Pratiwi Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia Background: Several clinical studies have shown increased level of urinary TGF-β1 in diabetic nephropathy patients and its correlation with urine ...
Sauriasari R, Pratiwi MY
doaj   +1 more source

TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]

, 2010
Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
core   +1 more source

Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter [PDF]

, 2010
The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer cells can switch their response to TGF-beta and use this cytokine as a potent oncogenic factor;
Hiller, L, Monteverde, M, Louise Hiller, Shah, Reshma, Kalna, G., Karin A. Oien, Jonathan A. Cooper, Maurer, M.E., O'Brien, Darren I, Jelena Mann, Oien, KA, Frame, MC, Frame, Margaret C., David C. K. Chu, Crook, T., Chu, David C K, Lo Nigro, Cristiana, Lattanzio, L., Orange, Clare, Spender, Lindsay C., Chu, D.C.K., Thurlow, JK, Thurlow, Johanna K., Shah, R, Linda J. Nicholson, Syed, Nelofer, Harris, Adrian L, Orange, Cl., O'Brien, Darren I., Maurer, Meghan E., Shah, R., Nicholson, LJ, Hiller, Louise, Cooper, J.A., Inman, GJ, Monteverde, M., O'Brien, DI, West, CM, Mann, Jelena, Inman, Gareth J., Harris, AL., Syed, N, Cristiana Lo Nigro, Buffa, FM, Darren I. O’Brien, West, CML, Gasco, Milena, Smith, P, Crook, Tim, Monteverde, Martino, Meghan E. Maurer, Buffa, Francesca M., Kalna, Gabriela, O Brien, DI, Patridge, Max, Hannigan, A., Patridge, M., Paul Smith, Francesca M. Buffa, Cooper, Jonathan A, Mann, J, Oien, Karin A, Crook, T, Spender, Lindsay C.; id_orcid, Reshma Shah, Smith, Paul J., Lattanzio, L, Orange, C, Catharine M. L. West, Kalna, G, Cooper, JA, Max Patridge, Smith, Paul, Johanna K. Thurlow, Margaret C. Frame, Nicholson, Linda J., O'Brien, D.I., Spender, LC, and Gareth J. Inman, Buffa, Francesca M, O'Brien, Darren I., West, Catharine M L, Herrera, Blanca, Gasco, M., Adèle Hannigan, Smith, P., Frame, MC., Milena Gasco, Lo Nigro, C., Inman, Gareth J, Herrera, B, Oien, K.A., Frame, Margaret C, Laura Lattanzio, Gabriela Kalna, West, Catharine M. L., Nicholson, Linda J, Tim Crook, West, C.M.L., Nelofer Syed, Chu, DCK, Blanca Herrera, West, Catharine M L; id_orcid, Hannigan, Adèle, Thurlow, Johanna K, Chu, DC, Mann, J., Spender, Lindsay C, Gasco, M, Clare Orange, Martino Monteverde, Patridge, M, Buffa, F.M., Maurer, Meghan E, David C.K. Chu, Chu, David C. K., Nicholson, L.J., Harris, AL, Spender, L.C., Lindsay C. Spender, Catharine M.L. West, Herrera, B., Hannigan, A, Maurer, ME, Cooper, Jonathan A., Oien, Karin A., Lo Nigro, C, Adrian L. Harris, Inman, G.J., Gareth J. Inman, Harris, Adrian L., Thurlow, J.K., Syed, N., Lattanzio, Laura   +133 more
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Splenic CD8(+) T cells secrete TGF-beta 1 to exert suppression in mice with anterior chamber-associated immune deviation [PDF]

, 2009
Background CD8(+) regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID).
Hao He, Lin, X.M., Peizeng Yang, Jiang, L.Q., Hongyan Zhou, Aize Kijlstra, Liqiong Jiang, Huang, X.K., Yang, P.Z., He, H., Zhou, H.Y., Xiaomin Lin, Xiangkun Huang, Kijlstra, A.   +13 more
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TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]

, 2010
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius, Philippa T K Saunders, Critchley, Hilary O. D., Kane, N.M., Hilary O D Critchley, Dey, Sudhansu Kumar, Kane Nicole M., Jan J Brosens, Marius Jones, Rodney W Kelly, Philippa T. K. Saunders, Jones, M., Kelly, Rodney W., Kane, Nicole M., Saunders Philippa T. K., Nicole M Kane, Jones, Marius, Brosens Jan J., Brosens, J.J., Kelly, R.W., Saunders, Philippa T. K., Jan J. Brosens, Hilary O. D. Critchley, Saunders, P.T.K., Brosens, Jan J., Saunders, Philippa T. K.; id_orcid, Critchley, H.O.D., Critchley Hilary O. D., Kelly Rodney W., Rodney W. Kelly, Nicole M. Kane   +30 more
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Bacterial meningitis: the role of transforming growth factor-Beta in innate immunity and secondary brain damage [PDF]

, 2007
Project 6 of the NCCR 'Neural Plasticity and Repair' focuses on mechanisms of immunity and tissue damage in autoimmune and infectious diseases of the central nervous system (CNS).
Malipiero, U, Malipiero, Ursula, Pfister, W, Fontana, Adriano, Koedel, U, Pfister, Walter, Fontana, A, Koedel, Uwe   +7 more
core   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M, Sultan, Ali A, J. Brian de Souza, de Souza, J Brian, Eleanor M. Riley, Corran, Patrick H, Patrick H. Corran, Omer, Fakhreldin M, Riley, EM, Sultan, AA, Corran, PH, Ali A. Sultan, Omer, FM, de Souza, JB, Fakhreldin M. Omer   +14 more
core   +1 more source