Results 171 to 180 of about 528,953 (331)

TH1 identity [PDF]

Nature Immunology, 2014
openaire   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Toward a Rational Design of Conjugated Copolymers with Oxygenated Side Chains for Boosting Thermoelectric Properties

Advanced Energy Materials, EarlyView.
The molecular design strategy that integrates both side chain and backbone engineering in diketopyrrolopyrrole‐based conjugated polymers to identify the optimal balance between doping efficiency and microstructural order is demonstrated. Comprehensive spectroscopic, electrochemical, morphological, and structural characterizations reveal that the ...
Taewoong Han, Suhui Sim, Hoimin Kim, Taewoong Yoon, Hyungju Ahn, Seungjoo Chang, Namgyu Park, Hajeong Kim, Shabaz Alam, Dongki Lee, Sungjun Park, Sungjoo Lee, Jaewon Lee, Boseok Kang   +13 more
wiley   +1 more source

Sequential Monte Carlo with likelihood tempering and parallel implementation for uncertainty quantification

AIChE Journal, EarlyView.
Abstract Bayesian estimation enables uncertainty quantification, but analytical implementation is often intractable. As an approximate approach, the Markov Chain Monte Carlo (MCMC) method is widely used, though it entails a high computational cost due to frequent evaluations of the likelihood function.
Tatsuki Maruchi, Tomoyuki Yajima, Yoshiaki Kawajiri   +2 more
wiley   +1 more source

Unusual bonding situations in Th(iv) and U(iv)-Al(iii) pnictogen complexes. [PDF]

Chem Sci
Mahawar P, Wang G, Ward RJ, Kelley SP, Maron L, Walensky JR.   +5 more
europepmc   +1 more source

Self‐Sensing Artificial‐Muscle‐Empowered Humanlike Perception, Interaction, and Positioning

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The proposed self‐sensorized artificial muscle (SSAM) can sense its length change as small as 0.01 mm via a seamlessly integrated multi‐segment induction coil. The SSAM provides accurate length information regardless of its loadings, driving pressure, or muscle design, adequate for robust data‐driven feedback control.
Houping Wu, Chenchen Li, Yufeng Wang, Zhengyan Wang, Yulian Peng, Zhipeng Wei, Hongbo Wang   +6 more
wiley   +1 more source

Tryptophan metabolism reprogramming regulates Th1/Th2 immune balance and inhibits mast cell activation. [PDF]

Amino Acids
Huang D, Huang D, Su L, He C, Zhang X, Peng J, Fan L, Cao Y, Chen L, Tong H.   +9 more
europepmc   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Improvement in Th1/Th2 balance and endometrial receptivity after hysteroscopic surgery in patients with cesarean scar disorder: a case report. [PDF]

Matern Health Neonatol Perinatol
Orita Y, Iwakawa T, Takeuchi K.
europepmc   +1 more source

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source