Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. [PDF]
Satoru Takahashi+6 more
openalex +1 more source
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang+16 more
wiley +1 more source
IL-18 production is required for the generation of a Th1 response during experimental chromoblastomycosis. [PDF]
Ferreira LG, de Almeida SR.
europepmc +1 more source
Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis [PDF]
Stephen R. Holdsworth+2 more
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In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han+10 more
wiley +1 more source
<i>Porphyromonas gingivalis</i> exacerbates experimental autoimmune encephalomyelitis by driving Th1 differentiation via ZAP70/NF-κB signaling. [PDF]
Dai D+7 more
europepmc +1 more source
Interleukin-12, a key cytokine in Th1-mediated autoimmune diseases
Luciano Adorini
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Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8+ T cells. [PDF]
Violeta Rus+4 more
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Engineering the Immune Response to Biomaterials
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam+12 more
wiley +1 more source