Diverse Roles of Semaphorins on T Cell Activation, Differentiation, Migration, and Effector Functions. [PDF]
Ma H, Gounni AS, Su RC, Kung SKP.
europepmc +1 more source
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang +4 more
wiley +1 more source
Do CSR Committees Pay Off? Direct and Indirect Links to Financial and ESG Performance
ABSTRACT Corporate boards increasingly delegate sustainability oversight to dedicated CSR committees, yet evidence on whether these committees improve corporate performance remains mixed. This study argues that part of this inconsistency arises because prior research often emphasizes overall associations between CSR committees and performance without ...
Ana Isabel Lopes
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Efficacy of <i>Mycobacterium vaccae</i> and vitamin D combination therapy in initial smear-negative pulmonary tuberculosis: a prospective study. [PDF]
Gu R, Wang L.
europepmc +1 more source
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley +1 more source
Th1/Th17-linked transcription factors TBX21 and RORC were associated with clinical response to rituximab in treatment-resistant schizophrenia. [PDF]
Bylund S +4 more
europepmc +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Iron overload is associated with increased susceptibility to pulmonary Pythium insidiosum infection in mice. [PDF]
Zhu D +6 more
europepmc +1 more source
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Refined single-cell profiling captures a CCR5<sup>high</sup> CD4<sup>+</sup> cytotoxic T-cell precursor in multiple sclerosis. [PDF]
van Puijfelik F +17 more
europepmc +1 more source

