Results 191 to 200 of about 318,750 (310)

<i>Mycobacterium tuberculosis</i> suppresses protective Th17 responses during infection. [PDF]

Elife
Zilinskas A, Balakhmet A, Fox D, Ni HM, Agudelo C, Samani H, Stanley SA.   +6 more
europepmc   +1 more source

Elevated RIPK2 Expression in Atopic Dermatitis Skin Is Associated with Mixed Th1/Th2 Cytokine Responses in CD4⁺ T Cells. [PDF]

Int J Mol Sci
Mubariki R, Khamaysi Z, Kaabour E, Salih M, Belity T, Toubi E, Blacher E, Vadasz Z.   +7 more
europepmc   +1 more source

Combined radiofrequency and topical exosomes in atrophic vulvar lichen sclerosus: A case report

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatological‐gynecological condition. Conventional first‐line treatment comprises topical corticosteroids; however, many patients remain refractory. Energy‐based devices, including radiofrequency (RF), have shown promising results in VLS, with symptomatic and functional improvement ...
Luisa Mendonca de Oliveira, Narciso DiLorenzo Machado Dias, Jacqueline Maia Ferraz, Patricia da Silva Oliveira   +3 more
wiley   +1 more source

Region-specific QCT thresholds for osteoporosis assessment in the thoracic spine: why lumbar cut-offs fail. [PDF]

BMC Musculoskelet Disord
Klockner FS, Jäckle K, Malik HA, Roch J, Meier MP, Lehmann W, Weiser L.   +6 more
europepmc   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

The proteinase-activated receptor-2 mediates protective immunity in early experimental leishmaniasis. [PDF]

Emerg Microbes Infect
Kusche Y, Münck N, Nemetschke L, Roebrock K, Fischer-Riepe L, Nattkemper E, Vischedyk K, Steinhoff M, Roth J, Sunderkötter C, Ehrchen J.   +10 more
europepmc   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Chromatin triggers tissue-specific immunity in 3D. [PDF]

Immunity
McKeever J, Koh AS.
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

2'-deoxyinosine ameliorates multiple sclerosis through modulating Th1/Th2 and Th17/Treg cell balance with potential involvement of AMPK phosphorylation. [PDF]

Front Pharmacol
Wang D, Zhu J, Wang Z, Guo Z, Zhu Y, He C.   +5 more
europepmc   +1 more source