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Th1-, Th17- und Th1+17-Zellen

Zeitschrift für Rheumatologie, 2011
T-Helfer-Zellen tragen mit der Sekretion von Zytokinen zur Induktion und Aufrechterhaltung rheumatischer Entzundungen bei. Die Untersuchung von Interferon-γ-produzierenden Th1-Zellen, Interleukin-17-produzierenden Th17-Zellen und die vor Kurzem beschriebenen Th1+17-Zellen konnten Einblicke in pathophysiologische Mechanismen rheumatischer Entzundungen ...
H.-D. Chang   +2 more
openaire   +1 more source

Th1/Th2 cells

Inflammatory Bowel Diseases, 1999
A large body of evidence indicates the existence of functionally polarized CD4+ T-cell responses based on their profile of cytokine secretion. Type 1 T helper (Th1) cells produce interferon-gamma, interleukin (IL)-2, and tumour necrosis factor (TNF)-beta, which activate macrophages and are responsible for cell-mediated immunity and phagocyte-dependent ...
openaire   +2 more sources

Th1-???????????????????? ?????????????????? ?? ???????????? ???? ???????????????? ?????????? ????????-??????????????????

2011
???????????? ?????????????????? ???????????????????????? ?????????????????? ?????????????????????? ?????????????????? ?? ???????? ?????????????????? ???????????? ?????? ?????????????????? ???????????? ????????-???????????????????? ?????????? ?????????????????????? ???????????? TNF-??, INF-?? ?? IL-2 ?? ?????????????????? ??????????. ????????????????????
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Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

Journal of Immunology, 1995
Dendritic cells are APCs that are unique in their potency to stimulate proliferation of primary Ag-specific responses in vitro and in vivo. In this study, we demonstrate that dendritic cells can produce IL-12, a dominant cytokine involved in the ...
S. Macatonia   +9 more
semanticscholar   +1 more source

Th1/Th2 Cross Regulation

Journal of Theoretical Biology, 1994
We present and analyze a model for the cross-regulation of the Th1 and Th2 helper cell subsets during an immune response by the regulatory cytokines interferon-gamma (IFN)-gamma) and interleukin-10 (IL-10). IFN-gamma, secreted by Th1 cells, can inhibit the proliferation of Th2 cells.
M A, Fishman, A S, Perelson
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Sarcoidosis and Th1 chemokines.

La Clinica terapeutica, 2015
Many studies have shown high levels of the chemokine Interferon-γ-inducible protein 10 (IP-10) and its chemokine (C-X-C motif) receptor (CXCR) 3, expressed on Type-1 helper (Th1) lymphocytes, in bronchoalveolar lavage (BAL) and biopsy samples of patients with sarcoidosis.
openaire   +3 more sources

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