Results 151 to 160 of about 169,698 (304)
Central European Journal of ImmunologyIntroduction Curcumin is a multi-functional component with anti-inflammatory and immunomodulatory properties. Unregulated immune responses may be a causative factor in the development of gestational diabetes mellitus (GDM).
Zhenzhen Liu +4 more
doaj +1 more source
Increased frequency of circulating Th17 cells after TACE predicted improved survival.
, 2013 (A) Individuals in the high Th17 frequency group had significantly improved survival compared with those in the low Th17 frequency group 30 days after TACE. The samples were divided into two groups by the median Th17 frequency.
Bo Wang (86769) +7 more
core +1 more source
Modulation of Animal Gut Health by Milk Oligosaccharide
Animal Research and One Health, EarlyView.This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source
Th17 cells and their association with effector T cell subsets.
, 2013 (A–C) The correlations between the frequencies of circulating Th17 cells and IFN-γ+CD4+ T cells (A), IFN-γ+CD8+ T cells (B), and Treg (C) cells were evaluated.
Bo Wang (86769) +7 more
core +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Role of CD20+T lymphocytes in the pathogenesis of multiple sclerosis
Медицинская иммунологияCD3+CD20+T lymphocytes are a population of T cells that, along with standard T cell markers, express the atypical membrane molecule CD20 (a traditional B cell marker).
N. S. Glebezdina
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T cells, the Next Big Target in Axial Spondyloarthritis?
Arthritis &Rheumatology, EarlyView.Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley +1 more source
The AP-1 transcription factor JunB is required for Th17 cell differentiation
, 2017 Interleukin (IL)-17-producing T helper (Th17) cells are crucial for host defense against extracellular microbes and pathogenesis of autoimmune diseases. Here we show that the AP-1 transcription factor JunB is required for Th17 cell development.
Xuefeng Duan +14 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis. Characterizing these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next ...
James A. Stanway +13 more
wiley +1 more source
Hail Journal of Health SciencesBackground: Perianal fistulizing Crohn’s disease (PFCD) remains a formidable complication of Crohn’s disease (CD), affecting up to 30%–50% of patients and associated with significant morbidity.
Alfadl Abdulfattah
doaj +1 more source