Results 141 to 150 of about 187,124 (359)

Characteristics of subpopulation composition of peripheral blood lymphocytes in children with different forms of congenital ichthyosis

Аллергология и Иммунология в Педиатрии
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D. G. Kuptsova, N. N. Murashkin, S. G. Makarova, R. A. Ivanov, K. O. Avetisyan, T. V. Radigina, O. V. Kurbatova, S. V. Petrichuk   +7 more
doaj   +1 more source

Permissive/Protective Interplay of Microbiota with T Cell Adaptive Immune Response in Colon Cancer [PDF]

Iranian Journal of Colorectal Research, 2016
Colon microbiota, as a complex and diverse population, has been shown to be either pro- or anti-tumorigenic, depending on itscontent. The composition of microbiota critically determines the differentiation, activation, and expansion of T cells by which ...
Zahra Mojtahedi, Somayeh Rezaeifard, Zahra Faghih   +2 more
doaj  

A multivariate Th17 metagene for prognostic stratification in T cell non-inflamed triple negative breast cancer

OncoImmunology, 2019
A diversity of T helper (Th) subsets (Th1, Th2, Th17) has been identified in the human tumor microenvironment. In breast cancer, the role of Th subsets remains controversial, and a systematic study integrating Th subset diversity, T cell inflammation ...
L. Faucheux, M. Grandclaudon, M. Perrot-Dockès, P. Sirven, F. Berger, A.S. Hamy, V. Fourchotte, A. Vincent-Salomon, F. Mechta-Grigoriou, F. Reyal, A. Scholer-Dahirel, M. Guillot-Delost, V. Soumelis   +12 more
doaj   +1 more source

The Immune Imbalance of Treg/Th17 in Otitis Media of Effusion Patients May be Related to PI3K/Akt/mTOR Signaling Activation in the Middle Ear Mucosa

, 2021
Xianhai Zeng
openalex   +1 more source

The immunomodulation role of Th17 and Treg in renal transplantation [PDF]

, 2023
Dan-Lei Huang, Yi-Ran He, Yujing Liu, Hongyu He, Zhun-Yong Gu, Yimei Liu, Wenjun Liu, Zhe Luo, Min‐Jie Ju   +8 more
openalex   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, EarlyView.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization

OncoImmunology, 2018
D-2-hydroxyglutarate (D-2HG) is released by various types of malignant cells including acute myeloid leukemia (AML) blasts carrying isocitrate dehydrogenase (IDH) gain-of-function mutations.
Martin Böttcher, Kathrin Renner, Raffaela Berger, Kristin Mentz, Simone Thomas, Zugey Elizabeth Cardenas-Conejo, Katja Dettmer, Peter J. Oefner, Andreas Mackensen, Marina Kreutz, Dimitrios Mougiakakos   +10 more
doaj   +1 more source

TAGAP activates Th17 cell differentiation by promoting RhoA and NLRP3 to accelerate rheumatoid arthritis development [PDF]

, 2023
Honggang Sun, Qi Jiang, Wenjing Fan, Xu-Yan Shen, Zhaowei Wang, Xin Wang   +5 more
openalex   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Next-Generation Therapeutics for Perianal Fistulizing Crohn’s Disease: The Anticipated Impact of IL-23 Inhibitors

Hail Journal of Health Sciences
Background: Perianal fistulizing Crohn’s disease (PFCD) remains a formidable complication of Crohn’s disease (CD), affecting up to 30%–50% of patients and associated with significant morbidity.
Alfadl Abdulfattah
doaj   +1 more source