Results 311 to 320 of about 187,124 (359)

<i>In vitro</i> generation of RORγt⁺ regulatory T cells reveals enhanced immunosuppressive function and OXPHOS-dependent metabolism. [PDF]

Front Immunol
Cipelli M, da Silva EM, Paredes LC, do Amaral MA, Padovani BN, Menezes-Silva L, Andrade-Oliveira V, Camara NOS.   +7 more
europepmc   +1 more source

Soluble gp130 inhibits Th17 polarization in neutrophilic asthma by blocking IL-6 <i>trans</i>-signaling in dendritic cells. [PDF]

Front Immunol
Zhu S, Yao Y, Lv T, Yao F, Xu J, Zhang A, Zhang F.   +6 more
europepmc   +1 more source

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Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10

Immunity, 2023
Summary Commensal microbes induce cytokine-producing effector tissue-resident CD4 T cells, but the function of these T cells in mucosal homeostasis is not well understood.
Ivaylo I Ivanov, Madeline Edwards, Harris H Wang   +2 more
exaly   +2 more sources

The pathogenicity of Th17 cells in autoimmune diseases

Seminars in Immunopathology, 2019
Keiko Yasuda, Yusuke Takeuchi, Keiji Hirota   +2 more
exaly   +2 more sources

Th17 cells in depression

Brain, Behavior, and Immunity, 2018
T helper 17 (Th17) cells have recently been implicated in depression, which adds to the list of several other diseases of the central nervous system (CNS) that are already known to involve Th17 cells. In CNS diseases, it is thought that the signature cytokine produced by Th17 cells, interleukin-17A (IL-17A), mediates the detrimental effects of Th17 ...
Eleonore Beurel, Jeffrey A Lowell
exaly   +4 more sources

IL-17 and Th17 Cells.

Annual Review of Immunology, 2009
CD4+T cells, upon activation and expansion, develop into different T helper cell subsets with different cytokine profiles and distinct effector functions. Until recently, T cells were divided into Th1 or Th2 cells, depending on the cytokines they produce.
T. Korn, E. Bettelli, M. Oukka, V. Kuchroo   +3 more
semanticscholar   +3 more sources

Human and murine Th17

Current Opinion in HIV and AIDS, 2010
The purpose of this review is to summarize the most recent discoveries in the field of phenotypic and functional characterization of human and murine Th17 cells.Human Th17 cells express CD161 and exclusively originate from CD161 precursors present in umbilical cord blood and newborn thymus in response to the combined activity of IL-1beta and IL-23.
ANNUNZIATO, FRANCESCO, COSMI, LORENZO, ROMAGNANI, SERGIO   +2 more
openaire   +2 more sources