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Current Opinion in HIV and AIDS, 2010
The purpose of this review is to summarize the most recent discoveries in the field of phenotypic and functional characterization of human and murine Th17 cells.Human Th17 cells express CD161 and exclusively originate from CD161 precursors present in umbilical cord blood and newborn thymus in response to the combined activity of IL-1beta and IL-23.
ANNUNZIATO, FRANCESCO +2 more
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The purpose of this review is to summarize the most recent discoveries in the field of phenotypic and functional characterization of human and murine Th17 cells.Human Th17 cells express CD161 and exclusively originate from CD161 precursors present in umbilical cord blood and newborn thymus in response to the combined activity of IL-1beta and IL-23.
ANNUNZIATO, FRANCESCO +2 more
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International Immunopharmacology, 2011
Naïve T cells are multipotential precursors that differentiate into various effector subsets, such as T helper type 1 (Th1) and Th2 cells, which are characterized by their distinct functions. The IL-17-producing T helper (Th17) cell has been recently identified as a new subset of the T helper cell and a mediator of inflammation associated with various ...
Akihiro, Kimura, Tadamitsu, Kishimoto
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Naïve T cells are multipotential precursors that differentiate into various effector subsets, such as T helper type 1 (Th1) and Th2 cells, which are characterized by their distinct functions. The IL-17-producing T helper (Th17) cell has been recently identified as a new subset of the T helper cell and a mediator of inflammation associated with various ...
Akihiro, Kimura, Tadamitsu, Kishimoto
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Changes of Th17/Tc17 and Th17/Treg cells in endometrial carcinoma
Gynecologic Oncology, 2014T helper 17 (Th17), T cytotoxic 17 (Tc17) and regulatory T (Treg) cells are important factors in the pathogenesis of inflammatory and autoimmune diseases. However, information concerning the roles of these cells in antitumor immunity or endometrial tumorigenesis remains limited.
Wenjing, Zhang +7 more
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Inflammasome activation and Th17 responses
Molecular Immunology, 2019Immune sensing of exogenous molecules from microbes (e.g., pathogen-associated molecular patterns) and nonmicrobial molecules (e.g., asbestos, alum, and silica), as well as endogenous damage-associated molecular patterns (e.g., ATP, uric acid crystals, and amyloid A) activates innate immunity by inducing immune-related genes, including proinflammatory ...
Jian Deng, Xiao-Qiang Yu, Pei-Hui Wang
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Nature Reviews Immunology, 2020
Febrile temperature increases the differentiation of T helper 17 (TH17) cells with a more pro-inflammatory, pathogenic phenotype, which could have implications for the pathogenesis of autoimmunity.
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Febrile temperature increases the differentiation of T helper 17 (TH17) cells with a more pro-inflammatory, pathogenic phenotype, which could have implications for the pathogenesis of autoimmunity.
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2011
CD4+ T helper (TH) lymphocytes represent a heterogeneous population of cells that play an essential role in adaptive immunity. In addition to type 1 (TH1) and type 2 (TH2) cells, a third subset of CD4+ TH effector cells have recently been discovered and named as type 17 (TH17), because of its unique ability to produce interleukin (IL)-17.
Francesco Annunziato +4 more
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CD4+ T helper (TH) lymphocytes represent a heterogeneous population of cells that play an essential role in adaptive immunity. In addition to type 1 (TH1) and type 2 (TH2) cells, a third subset of CD4+ TH effector cells have recently been discovered and named as type 17 (TH17), because of its unique ability to produce interleukin (IL)-17.
Francesco Annunziato +4 more
openaire +1 more source