Biochemistry and Biophysics Reports, 2023 Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan +7 more
doaj
Unstable Angina is a syndrome correlated to mixed Th17 and Th1 immune disorder [PDF]
arXiv, 2013 Unstable angina is common clinical manifestation of atherosclerosis. However, the detailed pathogenesis of unstable angina is still not known. Here, I propose that unstable angina is a mixed TH17 and TH1 immune disorder. By using microarray analysis, I find out that TH1 and TH17 related cytokine, cytokine receptor, chemokines, complement, immune ...
arxiv
Dopamine receptor D5 signaling plays a dual role in experimental autoimmune encephalomyelitis potentiating Th17-mediated immunity and favoring suppressive activity of regulatory T-cells [PDF]
, 2018 Indexación: Scopus.This work was supported by grants FONDECYT-1170093 (to RP) and FONDECYT-3160383 (to CP) from ‘‘Fondo Nacional de Desarrollo Científico y Tecnológico de Chile’’, AFB170004 (to RP) from ‘‘Comisión Nacional de Investigación Científica y ...
Carolina Prado +4 more
core +3 more sources
Sepsis is a syndrome with hyperactivity of TH17-like innate immunity and hypoactivity of adaptive immunity [PDF]
arXiv, 2013 Currently, there are two major theories for the pathogenesis of sepsis: hyperimmune and hypoimmune. Hyperimmune theory suggests that cytokine storm causes the symptoms of sepsis. On the contrary, hypoimmune theory suggests that immunosuppression causes the manifestations of sepsis.
arxiv
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4. [PDF]
, 2017 While it is recognized that aquaporin-4 (AQP4)-specific T cells and antibodies participate in the pathogenesis of neuromyelitis optica (NMO), a human central nervous system (CNS) autoimmune demyelinating disease, creation of an AQP4-targeted model with ...
Cruz-Herranz, Andrés +7 more
core +1 more source
Simulating the Dynamics of T Cell Subsets Throughout the Lifetime [PDF]
arXiv, 2013 It is widely accepted that the immune system undergoes age-related changes correlating with increased disease in the elderly. T cell subsets have been implicated. The aim of this work is firstly to implement and validate a simulation of T regulatory cell (Treg) dynamics throughout the lifetime, based on a model by Baltcheva.
arxiv
S1PR1 mediates Th17 cell migration from the thymus to the skin in health and disease
Frontiers in ImmunologyTh17 cells play crucial roles in host defense and the pathogenesis of autoimmune diseases in the skin. While their differentiation mechanisms have been extensively studied, the origin of skin Th17 cells remains unclear.
Jonas Engesser +17 more
doaj +1 more source
Upregulated TNFR Family Member Insufficient to Promote Apoptotic Cell Death in T Helper 17 Cells
Proceedings, 2018 Fas is the receptor of tumor necrosis family receptors (TNFR) and involves in apoptosis. Since discovery of T helper 17 cells (Th17) in 2005, which are defined as a new type of helper T cells, it has become clear that the dysregulated function Th17 cells
Tufan Utku Çalışkan, Ayten Nalbant
doaj +1 more source
Numerical Investigation of Graph Spectra and Information Interpretability of Eigenvalues [PDF]
arXiv, 2015 We undertake an extensive numerical investigation of the graph spectra of thousands regular graphs, a set of random Erd\"os-R\'enyi graphs, the two most popular types of complex networks and an evolving genetic network by using novel conceptual and experimental tools.
arxiv
Revolutionizing Single Cell Analysis: The Power of Large Language Models for Cell Type Annotation [PDF]
arXiv, 2023 In recent years, single cell RNA sequencing has become a widely used technique to study cellular diversity and function. However, accurately annotating cell types from single cell data has been a challenging task, as it requires extensive knowledge of cell biology and gene function. The emergence of large language models such as ChatGPT and New Bing in
arxiv