Journal of Immunology Research, 2021 Several studies showed that IL-17A was significantly increased in nasal polyps (NPs). However, the source and characteristics of IL-17A-producing cells in NPs were not fully understood.
Guangfu Xu +3 more
doaj +1 more source
Emergence of collective propulsion through cell-cell adhesion [PDF]
Phys. Rev. E 97, 042413 (2018), 2017 The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in collective cell migration. The model consists of an amoeba cell with polarized cell-cell adhesion, which is controlled by
arxiv +1 more source
A cell membrane model that reproduces cortical flow-driven cell migration and collective movement [PDF]
, 2023 Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a cluster, referred to as cluster migration, are poorly understood.
arxiv +1 more source
Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production [PDF]
, 2017 IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells.
Cherukur, Yesesri +8 more
core +1 more source
Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1
Nature, 2013 TH17 cells (interleukin-17 (IL-17)-producing helper T cells) are highly proinflammatory cells that are critical for clearing extracellular pathogens and for inducing multiple autoimmune diseases.
Chuan Wu +7 more
semanticscholar +1 more source
The role of Th17 cells and regulatory T cells in Coxsackievirus B3-induced myocarditis [PDF]
, 2011 IL-17-producing (Th17) and regulatory T (Treg) cells have been well established in the pathogenesis of many inflammatory diseases. To assess whether Th17 and Treg were altered in acute virus-induced myocarditis (AVMC) mice, we assessed Th17/Treg ...
Chen, Haozhu +10 more
core +1 more source
Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia. [PDF]
PLoS ONE, 2015 Several cell types are considered to be effector cells in bile duct injury in rhesus rotavirus (RRV)-induced experimental biliary atresia (BA). Here, we identified an increased T helper 17 (Th17) cell population in a BA mode. By depleting the Th17 cells,
Yong-Jun Liu +8 more
doaj +1 more source
Identification of Th1-polarized Th17 cells: solving the problem
Медицинская иммунология, 2023 Helper T cells producing IL-17 (Th17) have high plasticity: restimulation of lymphocytes in an inflammatory environment can induce their transformation into cells with another phenotype, and a shift towards Th1 is the most common.
E. M. Kuklina, N. S. Glebezdina
doaj +1 more source
A Th17 sejtek szerepe rheumatoid arthritisben [PDF]
, 2010 Th17 cells are the newly described subset of the CD4 + T lymphocytes. Activated Th17 cells are characterized by their ability to produce IL-17A and other pro-inflammatory cytokines.
Balog, Attila +7 more
core +2 more sources
Physical Confinement and Cell Proximity Increase Cell Migration Rates and Invasiveness: A Mathematical Model of Cancer Cell Invasion through Flexible Channels [PDF]
, 2022 Cancer cell migration between different body parts is the driving force behind cancer metastasis, which is the main cause of mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in locally stiff, yet flexible tissues. In our previous work, we developed a model for cell geometry evolution during invasion,
arxiv +1 more source