Results 51 to 60 of about 10,836,682 (383)
Th17 cells and HIV infection [PDF]
Current Opinion in HIV and AIDS, 2010 This review summarizes the recent literature about the potential perturbation and role of Th17 cells in HIV pathogenesis. We discuss the recent findings on Th17 deficiency in HIV/simian immunodeficiency virus (SIV) infection and how this deficiency may impact the mucosal host defenses, potentially contributing to chronic immune activation.Th17 cells ...
Aimee, Elhed, Derya, Unutmaz
openaire +2 more sources
Journal of Neuroinflammation, 2019 Background Toll-like receptor 4 (TLR4) is well known for activating the innate immune system; however, it is also highly expressed in adaptive immune cells, such as CD4+ T-helper 17 (Th17) cells, which play a key role in multiple sclerosis (MS) pathology.
Xuebin Qu +6 more
doaj +1 more source
Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology [PDF]
, 2016 The discovery of Th17 cell plasticity, in which CD4 + IL-17-producing Th17 cells give rise to IL-17/IFN-γ double-producing cells and Th1-like IFNγ+ ex-Th17 lymphocytes, has raised questions regarding which of these cell types contribute to ...
Brucklacher-Waldert, Verena +6 more
core +2 more sources
Haematologica, 2012 Background The levels and clinical relevance of Th17 cells and other interleukin-17-producing cells have not been analyzed in chronic lymphocytic leukemia.
Preetesh Jain +15 more
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Dysregulation of Th17 cells during the early post-transplant period in patients under calcineurin inhibitor based immunosuppression. [PDF]
PLoS ONE, 2012 Accumulating evidence suggests that Th17 cells play a role in the development of chronic allograft injury in transplantation of various organs. However, the influence of current immunosuppressants on Th17-associated immune responses has not been fully ...
Byung Ha Chung +9 more
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Survival Proteins Encourage Human T Helper 17 Cells to Escape from Cell Death
Proceedings, 2018 IL-17 producing T helper 17 (Th17) cells are identified as a distinct subset of CD4+ T helper cells. They play a role in immune response. Abnormal regulation of Th17 cells can play a role in different type of pathologies such autoimmune diseases and ...
Tuğçe Çimen, Ayten Nalbant
doaj +1 more source
Biochemistry and Biophysics Reports, 2023 Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan +7 more
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Th17 cells in human disease [PDF]
Immunological Reviews, 2008 Summary:Our understanding of the role of T cells in human disease is undergoing revision as a result of the discovery of T‐helper 17 (Th17) cells, a unique CD4+T‐cell subset characterized by production of interleukin‐17 (IL‐17). IL‐17 is a highly inflammatory cytokine with robust effects on stromal cells in many tissues.
Tesmer, Laura A. +3 more
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Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway. [PDF]
PLoS ONE, 2012 MSC display potent suppressive properties initially described a decade ago. More recently, MSC suppressive activities on T-cell effector pathways have been investigated.
Patricia Luz-Crawford +7 more
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Identification of Novel Molecular Markers of Human Th17 Cells
Cells, 2020 Th17 cells are important players in host defense against pathogens such as Staphylococcus aureus, Candida albicans, and Bacillus anthracis. Th17 cell-mediated inflammation, under certain conditions in which balance in the immune system is disrupted, is ...
Anna Sałkowska +7 more
semanticscholar +1 more source