Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice. [PDF]
Oncotarget, 2019 Background: Tolerance induces a regulated immune response to infection. We hypothesized that tolerance induction modulated profile of T regulatory cell (Treg) and T lymphocyte 17 (Th17) cells and is related cytokine released in septic animals.
Andrade MMC +6 more
europepmc +2 more sources
Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes [PDF]
Journal of Visualized Experiments, 2013 Th17 cells are a distinct subset of T cells that have been found to produce interleukin 17 (IL-17), and differ in function from the other T cell subsets including Th1, Th2, and regulatory T cells. Th17 cells have emerged as a central culprit in overzealous inflammatory immune responses associated with many autoimmune disorders. In this method we purify
Simone Bedoya +4 more
openalex +4 more sources
Analysis of Sodium Chloride Intake and Treg/Th17 Lymphocytes in Healthy Individuals and Patients with Rheumatoid Arthritis or Systemic Lupus Erythematosus. [PDF]
J Immunol Res, 2018 We assessed different immune parameters in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) with low (LSI) and high (HSI) sodium intake. Thirty-eight patients with RA, thirty-seven with SLE, and twenty-eight healthy subjects
Vitales-Noyola M +7 more
europepmc +2 more sources
Pathogenicity of In Vivo Generated Intestinal Th17 Lymphocytes is IFN&ggr; Dependent [PDF]
Journal of Crohn's and Colitis, 2018 T helper 17 [Th17] cells are crucially involved in the immunopathogenesis of inflammatory bowel diseases in humans. Nevertheless, pharmacological blockade of interleukin 17A [IL17A], the Th17 signature cytokine, yielded negative results in patients with Crohn's disease [CD], and attempts to elucidate the determinants of Th17 cells' pathogenicity in the
G. Nizzoli +16 more
semanticscholar +3 more sources
[Th17 lymphocytes in bacterial infections].
Postępy Higieny i Medycyny Doświadczalnej, 2015 Th17 cells are a relatively newly discovered subpopulation of helper CD4+ T lymphocytes. It has been shown that these cells may contribute to tissue damage during certain inflammatory and autoimmune diseases and also play an important role in antitumor ...
L. Szulc-Dąbrowska +4 more
semanticscholar +3 more sources
Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE [PDF]
Journal of Experimental Medicine, 2011 Th1 lymphocytes preferentially infiltrate into the spinal cord during EAE via a VLA-4–mediated mechanism while Th17 lymphocyte infiltration is dependent on LFA-1 expression.
Veit Rothhammer +6 more
openalex +2 more sources
Difference in Th1 and Th17 Lymphocyte Adhesion to Endothelium [PDF]
The Journal of Immunology, 2012 Abstract T cell subset-specific migration to inflammatory sites is tightly regulated and involves interaction of the T cells with the endothelium. Th17 cells often appear at different inflammatory sites than Th1 cells, or both subsets appear at the same sites but at different times.
Pilar Alcaide +7 more
openalex +5 more sources
Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA.
Mariángeles Noto Llana +13 more
doaj +3 more sources
Involvement of CD26 in Differentiation and Functions of Th1 and Th17 Subpopulations of T Lymphocytes [PDF]
Journal of Immunology Research, 2021 CD26, acting as a costimulator of T cell activation, plays an important role in the immune system. However, the role of CD26 in the differentiation of T cell subsets, especially of new paradigms of T cells, such as Th17 and Tregs, is not fully clarified.
Xiangli Zhao +5 more
doaj +4 more sources
[Role of Th17 lymphocytes in pathogenesis of colorectal cancer].
Postępy Higieny i Medycyny Doświadczalnej, 2014 Colorectal cancer (CRC) is estimated to be the first leading cause of death from cancer among men and women in the EU. Every year in Poland, 15,254 cases of CRC are diagnosed, and 10,501 patients die of the disease, making it the second leading cause of ...
J. Karczewski +3 more
semanticscholar +4 more sources