Results 21 to 30 of about 113,223 (329)

Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]

open access: yes, 2014
Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Marelli-Berg, F   +3 more
core   +7 more sources

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes [PDF]

open access: bronzeJournal of Visualized Experiments, 2013
Th17 cells are a distinct subset of T cells that have been found to produce interleukin 17 (IL-17), and differ in function from the other T cell subsets including Th1, Th2, and regulatory T cells. Th17 cells have emerged as a central culprit in overzealous inflammatory immune responses associated with many autoimmune disorders. In this method we purify
Simone Bedoya   +4 more
openalex   +4 more sources

Change of Th17 Lymphocytes and Treg/Th17 in Typical and Atypical Optic Neuritis. [PDF]

open access: yesPLoS One, 2016
Typical and atypical optic neuritis (ON) are two clinical types of autoimmune inflammatory diseases of the optic nerve that causes acute vision loss, and are difficult to distinguish in their early stages. The disturbance in the balance of Th17 and Treg lymphocytes is thought to play an essential role in these autoimmune inflammatory diseases.To detect
Cong H   +6 more
europepmc   +5 more sources

Cigarette smoking induces human CCR6+Th17 lymphocytes senescence and VEGF-A secretion. [PDF]

open access: yesSci Rep, 2020
AbstractChronic exposure to environmental pollutants is often associated with systemic inflammation. As such, cigarette smoking contributes to inflammation and lung diseases by inducing senescence of pulmonary cells such as pneumocytes, fibroblasts, and endothelial cells.
Baskara I   +10 more
europepmc   +5 more sources

Markers of Th1 polarized Th17 cells (literature review)

open access: yesActa Biomedica Scientifica, 2023
T helpers (Th) producing IL-17 (Th17) have high plasticity and under the influence of external conditions are able to redifferentiate into cells with a different phenotype, primarily in Th1-lymphocytes, forming a population that combines the ...
E. M. Kuklina, N. S. Glebezdina
doaj   +1 more source

CD4+ cells in autoimmune thyroid disease

open access: yesEndokrynologia Polska, 2021
The phenomenon of autoimmunity develops as a result of the triggering factor released by damaged cells. This leads to an infiltration of CD4+ cells involved in stimulating the effector cells cytotoxicity and stimulating the humoral response.
Szymon Janyga   +5 more
doaj   +1 more source

Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid Arthritis

open access: yesJournal of Immunology Research, 2022
Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized, among others, by tissue damage and activation/differentiation of proinflammatory lymphocytes.
Marlen Vitales-Noyola   +7 more
doaj   +1 more source

Lymphocyte Isolation, Th17 Cell Differentiation, Activation, and Staining [PDF]

open access: yesBIO-PROTOCOL, 2016
In vitro Th17 (α, β T helper cell which produce IL-17A, IL-17F and IL-22) differentiation has been routinely used for functional T cells studies. Here we describe a method for Th17 cell differentiation.
Pawan Kumar, Jay Kolls
openaire   +3 more sources

The Role of IL-17 and Th17 Lymphocytes in Autoimmune Diseases. [PDF]

open access: yesArch Immunol Ther Exp (Warsz), 2015
The end of twentieth century has introduced some changes into T helper (Th) cells division. The identification of the new subpopulation of T helper cells producing IL-17 modified model of Th1-Th2 paradigm and it was named Th17. High abilities to stimulate acute and chronic inflammation made these cells ideal candidate for crucial player in development ...
Tabarkiewicz J   +4 more
europepmc   +4 more sources

Th17 cell frequency and IL-17A production in peripheral blood of patients with non-small-cell lung cancer

open access: yesJournal of International Medical Research, 2020
Objective This study investigated the frequency of T-helper (Th)17 lymphocytes and production of cytokine interleukin (IL)-17 in peripheral blood of patients with non-small-cell lung cancer (NSCLC) and their use as a marker of clinical value.
Gang Chen   +8 more
doaj   +1 more source

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