Results 61 to 70 of about 709,386 (365)

The role of Th17 lymphocytes in pathogenesis of autoimmune arthritides [PDF]

Polish Journal of Public Health, 2014
Abstract Th17 cells are newly described population of lymphoctyes, that recruits neutrophils to the site of inflammation and activate inflammatory phenotype of various tissues. They also play a pivotal role in autoimmune diseases and cancers. These cells secrete mainly different isoforms of IL-17, but also IL-21 and IL-22.
Beata Rybojad, Magdalena Bańka, Katarzyna Pogoda, Maria Pyszniak, Jacek Tabarkiewicz   +4 more
openaire   +2 more sources

Molecular Mechanisms of Kidney Injury and Repair in Arterial Hypertension [PDF]

, 2019
The global burden of chronic kidney disease is rising. The etiologies, heterogeneous, and arterial hypertension, are key factors contributing to the development and progression of chronic kidney disease. Arterial hypertension is induced and maintained by
Eckardt, Kai-Uwe, Sievers, Laura Katharina   +1 more
core   +2 more sources

Immune response to Bifidobacterium bifidum strains support Treg/Th17 plasticity.

PLoS ONE, 2011
In this work we analyzed the immune activation properties of different Bifidobacterium strains in order to establish their ability as inductors of specific effector (Th) or regulatory (Treg) responses. First, we determined the cytokine pattern induced by
Patricia López, Irene González-Rodríguez, Miguel Gueimonde, Abelardo Margolles, Ana Suárez   +4 more
doaj   +1 more source

T-bet Regulates the Fate of Th1 and Th17 Lymphocytes in Autoimmunity [PDF]

The Journal of Immunology, 2007
Abstract IL-17-producing T cells (Th17) have recently been implicated in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), an animal model for the human disease multiple sclerosis. However, little is known about the transcription factors that regulate these cells.
Anne R. Gocke, Michael K. Racke, Sara C. Northrop, Petra D. Cravens, Rehana Z. Hussain, Li Hong Ben, Amy E. Lovett-Racke   +6 more
openaire   +3 more sources

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]

, 2009
Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
core   +1 more source

Autosomal recessive hyper‐IgE syndrome due to DOCK8 deficiency: An adjunctive role for omalizumab

Journal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 222-226, December 2022., 2022
We report a rare case of AR‐HIES with DOCK8 deficiency in a young male that was successfully treated by infection management, skincare, diet elimination, and omalizumab. Abstract Autosomal recessive hyper‐IgE syndrome (AR‐HIES) is a rare primary immunodeficiency disorder characterized by high serum IgE levels, recurrent viral skin infections, severe ...
Kim Han Nguyen, Quynh Anh Nguyen, Mai Hoang Tran, Thu Thuy Can, Mai Thi Vu, Nam Sy Vo, Hieu Chu Chi, Sheryl van Nunen, Dinh Van Nguyen   +8 more
wiley   +1 more source

Ultrasound inflammatory parameters and Treg/Th17 cell profiles in established rheumatoid arthritis

Advances in Rheumatology, 2019
Background Imbalance and disfuntion in regulatory T-cells (Tregs) and IL-17 producer lymphocytes (Th17) have been implicated in the pathogenesis of rheumatoid arthritis (RA).
Aline Defaveri do Prado, Melissa Cláudia Bisi, Deise Marcela Piovesan, Markus Bredemeier, Talita Siara Baptista, Laura Petersen, Moises Evandro Bauer, Inês Guimarães da Silveira, José Alexandre Mendonça, Henrique Luiz Staub   +9 more
doaj   +1 more source

Hepatic lymphocytes involved in the pathogenesis of pediatric and adult non-alcoholic fatty liver disease

Scientific Reports, 2021
The immune response is critical in NAFLD pathogenesis, but the liver infiltrate’s composition and the role of each T cell population is still up for debate.
Victoria Cairoli, Elena De Matteo, Daniela Rios, Carol Lezama, Marcela Galoppo, Paola Casciato, Eduardo Mullen, Cecilia Giadans, Gustavo Bertot, María Victoria Preciado, Pamela Valva   +10 more
doaj   +1 more source

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal, Al-Mousawi, Allen, Almawi, Anderson, Andreae, Annunziato, Anthony, Arya, Avnir, Avnir, Baatjes, Banchereau, Banuelos, Banuelos, Barnes, Beck, Beck, Belvisi, Bengtsson, Benson, Bentley, Berdeli, Blotta, Borish, Brack, Bradding, Braun, Brozek, Burger, Buttgereit, Buttgereit, Buttgereit, Capell, Chan, Chatham, Chen, Choo, Chung, Clutterbuck, Cohn, Corbera-Bellalta, Cosmi, Cosmi, Crocker, Cronstein, Damsker, Dao Nguyen, Daynes, Daynes, de Castro Kroner, Deng, Dolhain, Dorner, Dougherty, Durham, Eichenauer, Eichhorst, Eklund, Erin, Espigol-Frigole, Fanouriakis, Finotto, Firestein, Firestein, Franchimont, Franchimont, Franco, Gao, Geginat, Gemou-Engesaeth, Gladman, Gomes, Gracie, Gregersen, Greiner, Grindebacke, Guiducci, Gupta, Hadji, Hagan, Hahn, Hamid, Hamid, Hanahan, Haneda, Hartl, Hasegawa, Hawrylowicz, Hehlmann, Heidari, Heiman, Hellmich, Hermann-Kunz, Hernandez-Rodriguez, Hicsonmez, Hirahara, Hoelzer, Hollenberg, Hu, Hussain, Hutchison, Inaba, Ismaili, Jacobi, Jacobi, Jee, Jennette, Jiang, Jin, Jing, John, Jones, Jones, Kansal, Kaplan, Karagiannidis, Kirwan, Klarenbeek, Klassen, Kleiman, Klein, Klimek, Kotake, Kotake, Kovalovsky, Kremer, Kruth, Leppert, Li, Li-Weber, Liberman, Liles, Lim, Lin, Linden, Liu, Loetscher, Lohse, Lugar, Luo, Machold, Maggi, Maneechotesuwan, Manzoni, Martinez-Sanchez, Maruotti, Matsui, Matteson, McDonough, Meagher, Mercieca, Merrill, Miller, Miltenburg, Mitra, Miyasaka, Miyaura, Moallem, Morita, Moynihan, Mozo, Muehling, Munck, Muraro, Murphy, Naseer, Neeck, Neeck, Nicholson, O'Byrne, O'Byrne, Oakley, Oakley, Ochiai, Odendahl, Oppong, Ospelt, Parrillo, Patel, Pawankar, Pearson, Perez-Guerrero, Pers, Picchianti-Diamanti, Pratt, Pratt, Pui, Qin, Quinn, Radich, Rainer, Rak, Ramirez, Rank, Ratman, Refojo, Reichardt, Rider, Ring, Robinson, Robinson, Ronnblom, Ruiz-Arruza, Saadoun, Sallusto, Samson, Samson, Santos, Schacke, Schacke, Scherlinger, Schmitz, Schug, Shah, Shaw, Shlomchik, Siegel, Smith, Smolen, Smolen, Song, Stahn, Stahn, Stellato, Stone, Strehl, Strehl, Tanaka, Terrades-Garcia, Theofilopoulos, Thomas, Thomas, Till, Tuckermann, Turjeman, Ulmansky, Umetsu, van der Geest, van Oosterhout, Vandevyver, Verhoef, Verstappen, von Bernus, von Hertzen, Waknine-Grinberg, Walker, Wang, Wassenberg, Watanabe, Wen, Weyand, Weyand, Wheatley, Wikstrom, Willemze, Wills-Karp, Wills-Karp, Wollenberg, Wollenberg, Wright, Wu, Wuthrich, Xystrakis, Yamamoto, Yan, Yang, Ying, Zubiaga   +268 more
core   +1 more source

Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms. [PDF]

PLoS ONE, 2013
Appropriate dendritic cell processing of the microbiota promotes intestinal homeostasis and protects against aberrant inflammatory responses. Mucosal CD103(+) dendritic cells are able to produce retinoic acid from retinal, however their role in vivo and ...
Patrycja Konieczna, Ruth Ferstl, Mario Ziegler, Remo Frei, Dirk Nehrbass, Roger P Lauener, Cezmi A Akdis, Liam O'Mahony   +7 more
doaj   +1 more source