Results 71 to 80 of about 709,386 (365)
82 Th17 lymphocytes in children with asthma and cystic fibrosis
Guenka Petrova+7 more
openalex +3 more sources
TL1A/DR3 axis involvement in the inflammatory cytokine network during pulmonary sarcoidosis [PDF]
BACKGROUND: TNF-like ligand 1A (TL1A), a recently recognized member of the TNF superfamily, and its death domain receptor 3 (DR3), firstly identified for their relevant role in T lymphocyte homeostasis, are now well-known mediators of several immune ...
A. Cabrelle+45 more
core +1 more source
PathRTM: Real-time prediction of KI-67 and tumor-infiltrated lymphocytes [PDF]
In this paper, we introduce PathRTM, a novel deep neural network detector based on RTMDet, for automated KI-67 proliferation and tumor-infiltrated lymphocyte estimation. KI-67 proliferation and tumor-infiltrated lymphocyte estimation play a crucial role in cancer diagnosis and treatment.
arxiv
Deep generative selection models of T and B cell receptor repertoires with soNNia [PDF]
Subclasses of lymphocytes carry different functional roles to work together to produce an immune response and lasting immunity. Additionally to these functional roles, T and B-cell lymphocytes rely on the diversity of their receptor chains to recognize different pathogens.
arxiv +1 more source
This study performed a longitudinal analysis of a comprehensive panel of 22 innate and adaptive immune cell phenotypes, including differentiated and senescent CD4+ and CD8+ cells, with incident diabetes risk among a U.S. community‐based population of older adults.
Nels C. Olson+9 more
wiley +1 more source
Diabetes mellitus type 2 is one of the most important non-infectious diseases in the modern world, being an important risk factor of cardiovascular disorders.
I. V. Kologrivova+5 more
doaj +1 more source
The role of dietary sodium intake on the modulation of T helper 17 cells and regulatory T cells in patients with rheumatoid arthritis and systemic lupus erythematosus [PDF]
We aimed at investigating whether the frequency and function of T helper 17 (Th17) and regulatory T cells (Treg) are affected by a restriction of dietary sodium intake in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
Alessandri, Cristiano+11 more
core +3 more sources
The thioredoxin system: Balancing redox responses in immune cells and tumors
The thioredoxin (TRX) system is a critical contributor to cellular redox homeostasis in all living cells. Here, we review the key roles of TRX for activation, proliferation, and responses in T cells, B cells, and myeloid cells. Further, we conceptualize how this knowledge may be therapeutically exploited for cancer treatment.
Jonathan Muri, Manfred Kopf
wiley +1 more source
The effect of habitual Western diet and salt‐reduced diet on the levels of systemic blood cytokines was analyzed in a placebo‐controlled nutritional intervention study. The results showed that reduced salt intake did not alter the concentrations of any of the analyzed 34 cytokines in blood.
Teemu Niiranen+4 more
wiley +1 more source
Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by destruction of the myelin sheath structure.
Rongzeng Liu+10 more
doaj +1 more source