Results 131 to 140 of about 10,689,174 (395)
Journal of Experimental Medicine, 2007 Although interferon γ (IFN-γ) secretion is essential for control of most intracellular pathogens, host survival often also depends on the expression of interleukin 10 (IL-10), a cytokine known to counteract IFN-γ effector functions.
Dragana Jankovic +9 more
semanticscholar +1 more source
Arthritis Care &Research, Volume 77, Issue 4, Page 513-521, April 2025.Objective To assess changes in gene expression following tofacitinib treatment and investigate transcription patterns as potential predictors of treatment response in patients with active juvenile idiopathic arthritis (JIA). Methods Whole‐blood samples were collected from patients with JIA at baseline and after 18 weeks of open‐label tofacitinib ...
Esraa Eloseily +7 more
wiley +1 more source
The Higher-Order Prover Leo-III (Extended Version) [PDF]
9th International Joint Conference on Automated Reasoning, IJCAR
2018, Oxford, UK, July 14-17, 2018, Proceedings, Springer, 2018 The automated theorem prover Leo-III for classical higher-order logic with Henkin semantics and choice is presented. Leo-III is based on extensional higher-order paramodulation and accepts every common TPTP dialect (FOF, TFF, THF), including their recent extensions to rank-1 polymorphism (TF1, TH1).
arxiv
Advanced Biology, Volume 9, Issue 4, April 2025.By systematizing a large body of evidence and propose a cascade relationship between protein homeostasis, endoplasmic reticulum stress, mitochondrial dysfunction, and pro‐fibrotic factor, providing a theoretical basis for ATII cells dysfunction as a possible pathophysiological initiating event for idiopathic pulmonary fibrosis.
Zhaoxiong Dong +6 more
wiley +1 more source
On complexified analytic Hamiltonian flows and geodesics on the space of Kahler metrics [PDF]
arXiv, 2013 In the case of a compact real analytic symplectic manifold M we describe an approach to the complexification of Hamiltonian flows [Se, Do1, Th1] and corresponding geodesics on the space of Kahler metrics. In this approach, motivated by recent work on quantization, the complexified Hamiltonian flows act, through the Grobner theory of Lie series, on the ...
arxiv
, 2003 Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
Gracie, J.A. +2 more
core +1 more source
Nature Immunology, 2012 Activation of Toll-like receptors (TLRs) by pathogens triggers cytokine production and T cell activation, immune defense mechanisms that are linked to immunopathology.
M. Raetz +12 more
semanticscholar +1 more source
Scalable Fabrication of Height‐Variable Microstructures with a Revised Wetting Model
Advanced Engineering Materials, EarlyView.Height‐variable microstructures are fabricated using a scalable CO2 laser machining approach, enabling precise control of wettability through structural gradients. Classical wetting models fail to capture height‐induced effects, necessitating a revised theoretical framework.
Prabuddha De Saram +2 more
wiley +1 more source
BMJ Open OphthalmologyIntroduction Rho-associated protein kinases (ROCKs) are a key regulator of T cell function, influencing a wide range of processes from activation to differentiation.
Tomohito Sato +5 more
doaj +1 more source
Wellcome Open Research, 2023 Background CD4+ Th1 cells producing IFN-γ are required to eradicate intracellular pathogens, however if uncontrolled these cells can cause immunopathology.
Marisol Alvarez-Martinez +7 more
doaj