Protein kinase D1 in myeloid lineage cells contributes to the accumulation of CXCR3<sup>+</sup>CCR6<sup>+</sup> nonconventional Th1 cells in the lungs and potentiates hypersensitivity pneumonitis caused by <i>S. rectivirgula</i>. [PDF]
Snyder JD +5 more
europepmc +1 more source
Author Correction: Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells. [PDF]
Zimmermann J +13 more
europepmc +1 more source
Corrigendum: Protein kinase D1 in myeloid lineage cells contributes to the accumulation of CXCR3<sup>+</sup>CCR6<sup>+</sup> nonconventional Th1 cells in the lungs and potentiates hypersensitivity pneumonitis caused by <i>S. rectivirgula</i>. [PDF]
Snyder JD +5 more
europepmc +1 more source
Plasticity and lineage commitment of individual T<sub>H</sub>1 cells are determined by stable T-bet expression quantities. [PDF]
Hegazy AN +14 more
europepmc +1 more source
IFN-γ-producing T<sub>H</sub>1 cells and dysfunctional regulatory T cells contribute to the pathogenesis of Sjögren's disease. [PDF]
Wang YH +14 more
europepmc +1 more source
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After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells.
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Journal of Leukocyte Biology, 2022AbstractLung squamous cell carcinoma (LUSC) is a common subtype of lung cancer. Th1 cells contribute to antitumor immune responses. However, there are few studies on Th1 cells in LUSC. CD8+ T cells are the main driver of the antitumor immunity, targeting tumor cells killing. Th1 cells play an important auxiliary role in this process.
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