The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu +11 more
wiley +1 more source
Contribution of Immune Responses to <i>Aedes aegypti</i> Saliva in Dengue Severity Among Patients with Atopic Dermatitis. [PDF]
Astuti RDI +3 more
europepmc +1 more source
We calculated the infiltration profiles of 28 immune cells within psoriatic immune microenvironment through single‐sample gene set enrichment analysis (ssGSEA) algorithm based on the eleven psoriasis related microarray datasets. Five immune‐related genes CXCL8, CXCL9, CCL18, RGS1, and SAMSN1 are associated with psoriasis, and establish a predictive ...
Tingjin Zheng +7 more
wiley +1 more source
Magnetoelectric nanoparticles drive TAF9B<sup>+</sup> T<sub>H</sub>2 cell expansion to alleviate inflammation. [PDF]
Song J +10 more
europepmc +1 more source
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre +10 more
wiley +1 more source
Exploratory Cytokine and Bone-Marker Patterns in a Proteoglycan-Induced Spondyloarthritis Mouse Model: Th1/Th2 Strain Comparison and TLR2/3/4 Knockout Readouts. [PDF]
Pallua JD, Schirmer M.
europepmc +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Evaluation of the Synergistic Effects of Mineral and Postbiotics Mixtures in Ameliorating Atopic Dermatitis in the NC/Nga Mouse Model. [PDF]
Jang Y +7 more
europepmc +1 more source
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro +7 more
wiley +1 more source
Exacerbations and Management of Asthma in Viral Lower Respiratory Tract Infections: The Significance of Immunoglobulin E. [PDF]
Akhavan M, Yousefi P, Tabibzadeh A.
europepmc +1 more source

