Plac1+ Tumor Cell‐Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer
Advanced Science, Volume 12, Issue 17, May 8, 2025.Meng et al. screen genes in the CTAs family and find Plac1 is specifically expressed in head and neck squamous cell carcinoma (HNSCC) cells. They reveal that Plac1 expression promotes HNSCC progression directly by activating PI3K/AKT signaling pathway.
Xiaoyan Meng +8 more
wiley +1 more source
Ethanol Feeding Impairs Innate Immunity and Alters the Expression of Th1‐ and Th2‐Phenotype Cytokines in Murine Klebsiella Pneumonia [PDF]
, 1998 David A. Zisman +6 more
openalex +1 more source
Advanced Science, Volume 12, Issue 18, May 15, 2025.The impact of topography on the secretome of adipose‐derived stem cells (ADSCs) has the potential for promoting tendon regeneration. The secretome generated from ADSCs on aligned structure has a potent effect in promoting cell migration, proliferation, tenogenic differentiation, macrophage M2 polarization, and tendon mechanical function recovery ...
Qiuzi Long +14 more
wiley +1 more source
Nitric Oxide and the Th2 Response Combine to Prevent Severe Hepatic Damage DuringSchistosoma mansoniInfection [PDF]
, 1999 Laura Rosa Brunet +3 more
openalex +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.Pancreatic cancer promotes the accumulation of mast cells in the tumor microenvironment. Tumor‐derived exosomes deliver miR‐188‐5p to tumor‐associated mast cells (TAMCs), enhancing TAMCs‐derived CXCL10 secretion by strengthening ERG transcription. TAMCs‐derived CXCL10 promotes tumor migration, stemness, and immunosuppressive environment.
Hanlin Yin +20 more
wiley +1 more source
An Altered Peptide Ligand Specifically Inhibits Th2 Cytokine Synthesis by Abrogating TCR Signaling [PDF]
, 1999 Alexander Faith +5 more
openalex +1 more source
Advanced Science, EarlyView.LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu +12 more
wiley +1 more source
Transplacental Priming of the Human Immune System to Environmental Allergens: Universal Skewing of Initial T Cell Responses Toward the Th2 Cytokine Profile [PDF]
, 1998 Susan L. Prescott +6 more
openalex +1 more source
Advanced Science, EarlyView.It is presented bioelectronics that exhibit exceptional adaptability to dynamic skin surfaces through an integrated structural and material design. These omnidirectionally stretchable, skin‐compliant, mechanically robust, and permeably biocompatible kirigami‐based devices minimize skin irritation and conductivity loss and offer new insights for the ...
Gyun Ro Kang +7 more
wiley +1 more source
Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. [PDF]
, 1998 Xinghua Zhou +3 more
openalex +1 more source