Results 161 to 170 of about 165,252 (249)

T cell and cytokine signatures as early predictors of response to IL-12/IL-23 inhibition in Crohn's disease. [PDF]

Front Immunol
Martín Arranz E, García-Ramirez L, Van Den Rym A, Suarez C, García-Solís B, Díaz-Iglesias N, López-Lera A, Corvillo F, Rueda García JL, Blanco-San Miguel P, Sánchez Azofra M, Poza Cordón J, Itan Y, López-Collazo E, Pérez de Diego R, Martín-Arranz MD.   +15 more
europepmc   +1 more source

Testing the factor structure of the International Trauma Questionnaire in a sample of violence‐exposed women living in Northern Ireland

Journal of Traumatic Stress, EarlyView.
Abstract The International Trauma Questionnaire (ITQ) assesses posttraumatic stress disorder (PTSD) and the disturbances in self‐organization (DSO) aspect of complex PTSD (CPTSD) per the ICD‐11. This study examined the ITQ's factor structure among violence‐ or abuse‐exposed women in Northern Ireland, a region with a history of conflict (i.e., “the ...
Marcin Owczarek, Mark Shevlin, Julie‐Ann Jordan, Ngozi Anyadike‐Danes, Claire McCartan, Susan Lagdon   +5 more
wiley   +1 more source

From static pathology to dynamic immunity: immunological plasticity and histopathological remodeling in atopic dermatitis and psoriasis. [PDF]

Front Immunol
Shen W, Yao Y, Ma YM, Xie XL, Tang SL, Wu Y, Zhong HJ, Li YM, Sun H.   +8 more
europepmc   +1 more source

Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos, Line Kibsgaard, Trine Bertelsen   +2 more
wiley   +1 more source

The evaluation of the plasma levels of interleukin 17A, thymic stromal lymphopoietin, interferon gamma, tumor necrosis factor-alpha and interleukins IL-2, IL-6, IL-23, and IL-31 in atopic dermatitis patients with dupilumab treatment. [PDF]

Front Immunol
Čelakovská J, Čermáková E, Boudkova P, Andrýs C.   +3 more
europepmc   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

STAT6: Multidimensional analysis from hematopoietic immune regulation to pathogenesis mechanisms and therapeutic targets in hematologic malignancies. [PDF]

Ann Hematol
Zhang S, Xiong S, Liu X, Cao J, Yue N, Wu C.   +5 more
europepmc   +1 more source

Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle, Claire Abasq‐Thomas, Claire Bocciarelli, Amélie Bourhis, Marina Alexandre, Belen Eguia, Laurent Misery, Numa Deydier   +7 more
wiley   +1 more source

Immunological Antagonism Between Psoriasis and Atopic Dermatitis: Pathways, Clinical Implications, and Therapeutic Perspectives. [PDF]

Clin Cosmet Investig Dermatol
Qin J, Meng Z, Min W, Wang X, Zou Y.
europepmc   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source