Results 161 to 170 of about 5,234,585 (193)

Th22 Cells and the Intestinal Mucosal Barrier

Frontiers in Immunology, 2023
T-helper 22 (Th22) cells represent a novel subset of CD4+ T cells that exhibit distinctive characteristics, namely the secretion of IL-22 while abstaining from secreting IL-17 and interferon-γ (IFN-γ). These cells serve as the primary source of IL-22, and both Th22 cells and IL-22 are believed to play a role in maintaining intestinal mucosal ...
Jieli Chen, Jun Yao
exaly   +4 more sources

Th22 Cells in Allergic Disease

Allergo Journal International, 2015
During the last decade, the field of T cell immunology started to confuse the scientific community. More and more subtypes of T helper cells and their counterparts in the innate immune system are described.
Stefanie Eyerich, Kilian Eyerich
exaly   +2 more sources

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The Biology and Functions of Th22 Cells

2014
T helper (Th) cells develop from naïve CD4(+) T cells under lineage-specific culture conditions and are nominated by their lineage-specific cytokines. Th22 cells, new players in adoptive immune responses, are identified by the production of interleukin (IL)-22.
Lei, Jia, Changyou, Wu
openaire   +2 more sources

Skin-Homing Th2/Th22 Cells in Papuloerythroderma of Ofuji

Dermatology, 2014
Papuloerythroderma of Ofuji (PEO) appears to be a T cell-mediated skin disease; however, the pathogenesis of PEO remains unclear. We report two cases of PEO and examine cytokine production and expression of skin-homing receptors in circulating T cells in the patients.
Yuichi, Teraki, Yumiko, Inoue
openaire   +2 more sources

An Increased Proportion of Circulating Th22 and Tc22 Cells in Psoriasis

Cellular Immunology, 2014
Psoriasis is a common dermatosis mediated by T cells. This study investigated the correlation of Th22 cells and Tc22 cells with psoriasis. A total of 30 psoriasis patients and 11 age- and sex-matched healthy controls were recruited for this study. The proportions of circulating Th22 and Tc22 cells, expression of aryl hydrocarbon receptor, and IL-22 ...
Li, Luan, Ying, Ding, Shixin, Han, Zhenying, Zhang, Xiaoming, Liu   +4 more
exaly   +3 more sources

Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis

Journal of Clinical Immunology, 2011
T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. The roles of Th22 cells in the pathophysiology of rheumatoid arthritis (RA) remain unsettled.CD4(+)IFNγ(-)IL17(-)IL-22(+) T cells (Th22 cells), CD4(+)IFNγ(-)IL-22(-)IL17(+) T cells (pure Th17 cells), CD4(+)IL17(+) T cells (Th17 cells), and CD4(+)IFNγ(+) T cells ...
Lei, Zhang, Jian-Min, Li, Xin-Guang, Liu, Dao-Xin, Ma, Nai-Wen, Hu, Yong-Gang, Li, Wei, Li, Yu, Hu, Shuang, Yu, Xun, Qu, Mei-Xiang, Yang, A-Lei, Feng, Guang-Hui, Wang   +12 more
openaire   +2 more sources

Induction of skin-pathogenic Th22 cells by epicutaneous allergen exposure

Journal of Dermatological Science, 2017
Atopic dermatitis (AD) is a common inflammatory skin disease with dysfunction of the skin barrier, an abnormal immune response and frequent allergies to environmental antigens like food antigens. Clinical observations suggest that certain diets can influence the course of AD.Here we compared the phenotype of food allergen-specific T cells activated ...
Ivana, Glocova, Jürgen, Brück, Julia, Geisel, Eva, Müller-Hermelink, Katja, Widmaier, Amir S, Yazdi, Martin, Röcken, Kamran, Ghoreschi   +7 more
openaire   +2 more sources

Elevated profiles of Th22 cells and correlations with Th17 cells in patients with immune thrombocytopenia

Human Immunology, 2012
T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. However, the role of Th22 cells in the pathophysiology of immune thrombocytopenia (ITP) remains unclear. Th22, Th17 and Th1 cells in both ITP patients and healthy controls were examined by flow cytometry. Plasma interleukin-22 (IL-22) level was measured by enzyme
Yu, Hu, Haiyan, Li, Lei, Zhang, Baozhong, Shan, Xingfang, Xu, Hong, Li, Xinguang, Liu, Shuqian, Xu, Shuang, Yu, Daoxin, Ma, Jun, Peng, Ming, Hou   +11 more
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Decreased circulating Th22 and Th17 cells in patients with aplastic anemia

Clinica Chimica Acta, 2015
Aplastic anemia (AA) is an immune-mediated disorder and mainly related to active destruction of hematopoietic cells by effector T lymphocytes. T helper (Th) 22 cells characterized as a novel subset of CD4+ T cells participate in the pathogenesis of autoimmune and hematological diseases.
Ting Lu, Yan Liu, Peng Li, Shuang Yu, Xiaoyang Huang, Daoxin Ma, Chunyan Ji   +6 more
openaire   +2 more sources