Results 91 to 100 of about 4,736,482 (176)

Herbal Extracts and Plant‐Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Food‐derived bioactives, herbal extracts, and standardized botanical products are being investigated as adjunctive strategies for atopic dermatitis. Their biological activity is shaped not only by plant source and nominal dose, but also by fermentation, drying, heating, extraction, food‐matrix binding, gastrointestinal transformation, and formulation ...
Muhuang Zeng, Qianlan Yuan, Shuojia Huang, Xiaofei Lu   +3 more
wiley   +1 more source

Triple Cytokine FluoroSpot Analysis of Human Antigen-Specific IFN-γ, IL-17A and IL-22 Responses

Cells, 2014
The involvement of T-helper (Th)1, Th17 and Th22 cell subsets, in immunity, as well as in pathological inflammatory reactions, makes it important to determine their relative proportion. A triple FluoroSpot detecting the hallmark cytokines of Th1 (IFN-γ),
Tomas Dillenbeck, Eva Gelius, Jenny Fohlstedt, Niklas Ahlborg   +3 more
doaj   +1 more source

Differential human Th22-lymphocyte response triggered by Aggregatibacter actinomycetemcomitans serotypes

, 2017
Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on lipopolysaccharide (LPS) antigenicity. When T lymphocytes were stimulated with these serotypes, different patterns of T-helper (Th)1 and Th17-type of ...
Rolando Vernal, Jaime Díaz-Zúñiga, Myriam Pujol, Leticia Rojas, Carla Alvarez, Gustavo Monasterio, Paola Carvajal, Samanta Melgar-Rodríguez, Alvarez C., Rojas L., Díaz-Zúñiga J., Melgar-Rodríguez S., Carvajal P., Vernal R., Monasterio G., Pujol M.   +15 more
core   +2 more sources

Inflammatory Aging‐Driven Immune Axis Imbalance and the Mechanisms of Chronicity in Elderly Atopic Dermatitis: A Systematic Review and Meta‐Analysis

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Background Elderly atopic dermatitis (elderly AD) is increasingly recognized as a chronic inflammatory skin disorder with immunopathological features that may differ from those in younger populations. Age‐related chronic low‐grade inflammation (inflammaging) may contribute to this phenotype, but its relationship with immune dysfunction and ...
Nan Wu, Yingjie Li, Xiaojie Wang, Yangyang Wu, Wenhao Yin   +4 more
wiley   +1 more source

Unbalanced Aryl Hydrocarbon Receptor Expression in Peripheral and Lesional T Cell Subsets of Atopic Dermatitis

Clinical, Cosmetic and Investigational Dermatology, 2023
Yu-Qing Hu, Jian-Zhong Zhang Department of Dermatology, Peking University People’s Hospital, Beijing, 100044, People’s Republic of ChinaCorrespondence: Jian-Zhong Zhang, Department of Dermatology, Peking University People’s Hospital, No. 11 South Avenue,
Hu YQ, Zhang JZ
doaj  

A novel, dual cytokine-secretion assay for the purification of human Th22 cells that do not co-produce IL-17A

, 2015
BACKGROUND Interleukin-22 is produced by certain T helper cells subsets (Th17, Th22) and at lower levels by γ-δ T cells, NKT and innate lymphoid cells. Th22 cells are unique immune cells that regulate tissue responses by IL-22 production.
C. A. Akdis, M. Wawrzyniak, Ochsner, U, Wirz, O, U. Ochsner, O. Wirz, W. van de Veen, Akdis, C A, Wawrzyniak, P, Wawrzyniak, M, van de Veen, W, Akdis, M, P. Wawrzyniak, M. Akdis, Ochsner U, Akdis M, van de Veen W, Akdis CA, Wawrzyniak P, Wawrzyniak M, Wirz O   +20 more
core   +1 more source

T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet.

, 2021
CD4+ T-helper 22 (Th22) cells are a phenotypically distinct lymphocyte subset that produces high levels of interleukin (IL)-22 without co-production of IL-17A.
Foster, PS, Hansbro, PM, Lochrin, A, Belz, GT, Plank, MW, Tay, HL, Barnes, JL, Asquith, K, Sabino, LR, Keely, S, Mayall, JR, Maltby, S, Kaiko, GE, Horvat, JC, Kim, RY, Lorena R. Sabino, Paul S. Foster, Richard Y. Kim, Jessica L. Barnes, Kelly Asquith, Simon Keely, Gabrielle T. Belz, Alyssa Lochrin, Philip M. Hansbro, Jemma R. Mayall, Maximilian W. Plank, Hock L. Tay, Gerard E. Kaiko, Steven Maltby, Jay C. Horvat   +29 more
core   +1 more source

Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome.

PLoS ONE, 2012
BackgroundImmunological mechanisms are increasingly recognized in the progression of myelodysplastic syndrome (MDS). Early-stage MDS (E-MDS) is characterized by autoimmune-mediated myelosuppression whereas late-stage MDS (L-MDS) involves immune evasion ...
Lin-lin Shao, Lei Zhang, Yu Hou, Shuang Yu, Xin-guang Liu, Xiao-yang Huang, Yuan-xin Sun, Tian Tian, Na He, Dao-xin Ma, Jun Peng, Ming Hou   +11 more
doaj   +1 more source

Medroxyprogesterone Acetate Decreases Th1, Th17, and Increases Th22 Responses via AHR Signaling Which Could Affect Susceptibility to Infections and Inflammatory Disease

Frontiers in Immunology, 2019
A synthetic progestin, medroxyprogesterone acetate (MPA), was used in a novel study to determine progestin effects on human purified macrophages and Th1, Th2, Th17, Th22 cells. MPA concentrations were equivalent to those in the serum of women after 6 and
Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Ornela Kullolli, Enrico Maggi, Enrico Maggi, Marylynn S. Barkley   +6 more
doaj   +1 more source

Circulating Th1, Th2, Th9, Th17, Th22, and Treg Levels in Aortic Dissection Patients

Mediators of Inflammation, 2018
Background. Previous studies demonstrated that the subsets of CD4+ T helper (Th) cells are closely related to vascular diseases, including atherosclerosis and hypertension.
Jing Ye, Yuan Wang, Zhen Wang, Qingwei Ji, Ying Huang, Tao Zeng, Haiying Hu, Di Ye, Jun Wan, Yingzhong Lin   +9 more
doaj   +1 more source