Current Knowledge of Th22 Cell and IL-22 Functions in Infectious Diseases [PDF]
Pathogens, 2023 T helper 22 (Th22) cells, a newly defined CD4+ T-cell lineage, are characterized by their distinct cytokine profile, which primarily consists of IL-13, IL-22 and TNF-α.
Kunyu Zhang +4 more
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Role of Th22 Cells in the Pathogenesis of Autoimmune Diseases [PDF]
Frontiers in Immunology, 2021 Upon antigenic stimulation, naïve CD4+T cells differentiate into different subsets and secrete various cytokines to exert biological effects. Th22 cells, a newly identified CD4+T cell subset,are distinct from the Th1, Th2 and Th17 subsets.
Qi Jiang +7 more
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The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation [PDF]
Cellular & Molecular Biology Letters, 2021 Background NOTCH signaling has been shown to play a role in the production of interleukin-22 (IL-22) by CD4+ T cells. Multiple T-helper (Th) cell populations secrete IL-22.
Chong Zeng +7 more
doaj +5 more sources
Role of Th22 Cells in Human Viral Diseases [PDF]
Frontiers in Medicine, 2021 Naive CD4+ T cells can differentiate into different cell subsets after receiving antigen stimulation, which secrete corresponding characteristic cytokines and thereby exert biological effects in various diseases.
Jianguang Gong +5 more
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TH9, TH17, and TH22 Cell Subsets and Their Main Cytokine Products in the Pathogenesis of Colorectal Cancer [PDF]
Frontiers in Oncology, 2019 In recent years, several newly identified T helper (TH) cell subsets, such as TH9, TH17, and TH22 cells, and their respective cytokine products, IL-9, IL-17, and IL-22, have been reported to play critical roles in the development of chronic inflammation ...
Guanglin Cui, Guanglin Cui
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Acteoside relieves mesangial cell injury by regulating Th22 cell chemotaxis and proliferation in IgA nephropathy [PDF]
Renal Failure, 2018 The existing therapies of IgA nephropathy are unsatisfying. Acteoside, the main component of Rehmannia glutinosa with anti-inflammatory and anti-immune effects, can improve urinary protein excretion and immune disorder.
Lu Gan +5 more
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T cells form distinct spatially restricted immune responses in synovium of patients with psoriasis arthritis and rheumatoid arthritis [PDF]
Frontiers in ImmunologyIntroductionPsoriatic arthritis (PsA) and rheumatoid arthritis (RA) are chronic, inflammatory joint diseases, causing progressive structural damage.
Nathalie J. Behr +15 more
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Shared Pathways between Psoriasis and Atopic Dermatitis [PDF]
Dermatology Practical & ConceptualIntroduction: Psoriasis and atopic dermatitis are leading examples of chronic inflammatory dermatoses with distinct clinical manifestations, pathogenesis, and demographic patterns. However, recent research has revealed overlapping immunological pathways
Federica Trovato +10 more
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T‐Cell Populations in Infancy After Maternal Probiotic Supplementation to Prevent Atopic Dermatitis [PDF]
Clinical and Translational AllergyBackground In the randomised, controlled study Probiotics in the Prevention of Allergy amongst Children in Trondheim (ProPACT), maternal probiotics given from 36 weeks pregnancy until 3 months post‐delivery while breastfeeding reduced atopic dermatitis ...
Dinastry Pramadita Zakiudin +6 more
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Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer [PDF]
Frontiers in ImmunologyIntroductionColorectal cancer (CRC) is a leading cause of cancer-related mortality. While screening has reduced incidence in older adults, cases of early-onset CRC (EOCRC), diagnosed before age 50, are rising, highlighting the need to understand its ...
Clara Sánchez-Menéndez +29 more
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