Results 21 to 30 of about 5,234,585 (193)

Th22 is the effector cell of thymosin β15-induced hair regeneration in mice

Inflammation and Regeneration
Background Thymosin beta family has a significant role in promoting hair regeneration, but which type of T cells play a key role in this process has not been deeply studied.
Nana Tao, Yuyuan Ying, Xie Xu, Qingru Sun, Yaoying Shu, Shiyu Hu, Zhaohuan Lou, Jianli Gao   +7 more
doaj   +3 more sources

Importance of Th22 Cell Disequilibrium in Immune Thrombocytopenic Purpura. [PDF]

Med Sci Monit, 2018
BACKGROUND The disequilibrium of T helper (Th) cells play an important role in the occurrence and development of immune thrombocytopenic purpura (ITP). Th22 cells, as a newly discovered subset of T lymphocytes, plays an important role in autoimmune disorders and inflammatory diseases.
Zhan FX, Li J, Fang M, Ding J, Wang Q.
europepmc   +4 more sources

Th22 cell accumulation is associated with colorectal cancer development. [PDF]

World J Gastroenterol, 2015
To investigate the expression of Th22 cells and related cytokines in colorectal cancer (CRC) tissues, and the probably mechanism.CRC tumor and paratumor tissues were collected to detect the expression levels of Th22 cells and of related cytokines by immunohistochemistry, flow cytometry and real-time quantitative polymerase chain reaction (RT-qPCR ...
Huang YH, Cao YF, Jiang ZY, Zhang S, Gao F.   +4 more
europepmc   +3 more sources

Th22 cells are associated with hepatocellular carcinoma development and progression

Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2014
Objective: IL-22-producing CD4+ T helper cells (Th22 cells) have been identified as major inducers of tissue inflammation and immune responses. Currently, no previous study explored the role of Th22 cells in the pathogenesis of hepatocellular carcinoma ...
Qin, Shanyu, Jiang, Haixing, Lu, Donghong, Zhou, You, Huang, Xiaoli, Ma, Shijia   +5 more
core   +3 more sources

Increased Th22 cell numbers in a general pediatric population with filaggrin haploinsufficiency: The Generation R Study. [PDF]

Pediatr Allergy Immunol, 2021
Background Mutations in the filaggrin gene (FLG) affect epidermal barrier function and increase the risk of atopic dermatitis (AD). We hypothesized that FLG mutations affect immune cell composition in a general pediatric population.
Looman KIM, van Mierlo MMF, van Zelm MC, Hu C, Duijts L, de Jongste JC, Nijsten T, Pardo LM, Kiefte-de Jong JC, Moll HA, Pasmans SGMA.   +10 more
europepmc   +2 more sources

Huangkui Capsule in Combination with Leflunomide Improves Immunoglobulin A Nephropathy by Inhibiting the TGF-β1/Smad3 Signaling Pathway

Clinics, 2021
OBJECTIVES: To investigate the efficacy and potential molecular mechanism of Huangkui capsule in combination with leflunomide (HKL) for the treatment of immunoglobulin A nephropathy (IgAN) METHODS: IgAN rat models were constructed by treating rats with ...
Shuwen Pei, Yan Li
doaj   +1 more source

Th17 and Th22 cells in psoriatic arthritis and psoriasis [PDF]

Arthritis Research & Therapy, 2013
Abstract Introduction The aim of this study was to characterize interleukin 17 (IL-17) and interleukin 22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial tissue (ST) in patients with psoriasis (Ps) and psoriatic arthritis (PsA).
Benham, Helen, Norris, Paul, Goodall, Jane, Wechalekar, Mihir D., FitzGerald, Oliver, Szentpetery, Agnes, Smith, Malcolm, Thomas, Ranjeny, Gaston, Hill   +8 more
openaire   +6 more sources

Circulating Th22 cells, as well as Th17 cells, are elevated in patients with renal cell carcinoma [PDF]

International Journal of Medical Sciences, 2021
T-helper (Th) 22 cells serve an essential role in different types of tumors and autoimmune diseases. No research has been conducted to study the role of Th22 cells in the pathogenesis of renal cell carcinoma (RCC). We aimed to evaluate the prognostic value of circulating Th22, Th17, and Th1 cells in RCC patients. Thirty-two newly diagnosed RCC patients
Peng, Zhiguo, Hu, Yu, Ren, Juchao, Yu, Nengwang, Li, Zeyan, Xu, Zhonghua   +5 more
openaire   +2 more sources

Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis [PDF]

Journal of Investigative Dermatology, 2010
Th17, Th22, and Th1 cells are detected in psoriatic skin lesions and implicated in psoriasis pathogenesis, but inflammatory T cell numbers in blood, as well as the relative importance of each cell type, is unclear. Using 7-color flow cytometry, circulating Th17, Th22, and Th1 cells were quantified in 21 untreated psoriatics and 17 healthy individuals ...
Kagami, Shinji, Rizzo, Heather L., Lee, Jennifer J., Koguchi, Yoshinobu, Blauvelt, Andrew   +4 more
openaire   +2 more sources

The clinical significance of intrahepatic Th22 cells in liver cirrhosis [PDF]

Advances in Clinical and Experimental Medicine, 2019
Th22 cells are a recently identified CD4+ T helper subset and have been implicated in the pathogenesis of certain diseases in humans, but the role of Th22 cells in liver cirrhosis (LC) remains unclear.The aim of the study was to investigate the expression and clinical significance of intrahepatic Th22 cells in LC tissues.Samples of liver tissue of 20 ...
Shanyu, Qin, Mei, Chen, Xiaoyun, Guo, Wei, Luo, Jiaxu, Wang, Haixing, Jiang   +5 more
openaire   +2 more sources