Results 41 to 50 of about 5,234,585 (193)

Increased Expressions of IL-22 and Th22 cells in the coxsackievirus B3-Induced mice acute viral myocarditis

Virology Journal, 2012
Background Recently, a new subset of T helper (Th) cell that predominantly secret cytokine interleukin-22 (IL-22) is identified, termed Th22 cells. The Th22 subset has been demonstrated to be involved in immunity and tissue inflammation.
Kong Qing, Wu Weifeng, Yang Fan, Liu Yanli, Xue Yimin, Gao Mengsha, Lai Wenyin, Pan Xiaofen, Yan Yuluan, Pang Yu, Deng Yuanhua   +10 more
doaj   +1 more source

A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis [PDF]

, 2015
OBJECTIVE: Helper T (Th) cell responses are critical for the pathogenesis of Helicobacter pylori-induced gastritis. Th22 cells represent a newly discovered Th cell subset, but their relevance to H. pylori-induced gastritis is unknown.
Wang, TT, Peng, LS, Liu, T, Mao, XH, Yang, HJ, Cheng, P, Li, BS, Li, WH, Chen, W, Zou, QM, Liu, XF, Zeng, M, Mao, FY, Yang, SM, Zuo, QF, Lv, YP, Zhuang, Y, Chen, N, Guo, H, Yang, LY, Pang, KC, Guo, G, Shi, Y   +22 more
core   +1 more source

T helper cell subsets specific for Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis.

PLoS ONE, 2014
BackgroundWe set out to determine the magnitude of antigen-specific memory T helper cell responses to Pseudomonas aeruginosa in healthy humans and patients with cystic fibrosis.MethodsPeripheral blood human memory CD4(+) T cells were co-cultured with ...
Hannah K Bayes, Stephen Bicknell, Gordon MacGregor, Tom J Evans   +3 more
doaj   +1 more source

Staphylococcal Exotoxins Induce Interleukin 22 in Human Th22 Cells [PDF]

International Archives of Allergy and Immunology, 2014
Background: We have shown previously that T cells from atopic dermatitis (AD) patients produce more IL-22 upon staphylococcal exotoxin stimulation compared to psoriasis patients and healthy controls. The role of staphylococcal exotoxins on polarized memory T helper (Th)22 cells which are enriched in inflamed AD skin remains elusive.
Margarete Niebuhr, Julia Mainardy, Annice Heratizadeh, Imke Satzger, Thomas Werfel   +4 more
openaire   +2 more sources

Levels of Th17, Th22, and Th17/Th22 are more drastically depleted by SIV infection in RB than PBMC.

, 2016
Comparison of frequencies (measured as percentages of total CD4+ T-cell populations) of circulating (A) and colorectal (B) Th17 (red), Th22 (blue), and Th17/Th22 (green) cells before (d.-20 p.i.) and after (d. 58 p.i.) SIV infection.
Luca Micci (427502), Mirko Paiardini (243070), Nicolas Chomont (175516), Rémi Fromentin (659658), Colleen S. McGary (430430), Sara Paganini (2172766), Emily S. Ryan (651787), Kirk Easley (356159)   +7 more
core   +1 more source

Th17 cells increase in RRMS as well as in SPMS, whereas various other phenotypes of Th17 increase in RRMS only

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2020
Background The nature and extent of inflammation seen in multiple sclerosis (MS) varies throughout the course of the disease. Changes seen in CD4+ T-helper cells in relapsing–remitting (RR) MS and secondary progressive (SP) MS might differ qualitatively ...
S Kalra, C Lowndes, L Durant, RC Strange, A Al-Araji, Clive P Hawkins, S John Curnow   +6 more
doaj   +1 more source

Medroxyprogesterone Acetate Decreases Th1, Th17, and Increases Th22 Responses via AHR Signaling Which Could Affect Susceptibility to Infections and Inflammatory Disease

Frontiers in Immunology, 2019
A synthetic progestin, medroxyprogesterone acetate (MPA), was used in a novel study to determine progestin effects on human purified macrophages and Th1, Th2, Th17, Th22 cells. MPA concentrations were equivalent to those in the serum of women after 6 and
Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Ornela Kullolli, Enrico Maggi, Enrico Maggi, Marylynn S. Barkley   +6 more
doaj   +1 more source

Increased AHR Transcripts Correlate With Pro-inflammatory T-Helper Lymphocytes Polarization in Both Metabolically Healthy Obesity and Type 2 Diabetic Patients

Frontiers in Immunology, 2020
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor whose transcription activity is regulated by small compounds provided by diet, xenobiotics, and metabolism.
Ru-xing Zhao, Ru-xing Zhao, Ru-xing Zhao, Qin He, Sha Sha, Jia Song, Jun Qin, Peng Liu, Yu-jing Sun, Lei Sun, Lei Sun, Xin-guo Hou, Xin-guo Hou, Xin-guo Hou, Li Chen, Li Chen, Li Chen   +16 more
doaj   +1 more source

The Cytokine Profile in Different Stages of Schistosomiasis Japonica

Pathogens, 2023
To explore and profile the level of cytokines in the sera of patients infected with Schistosoma japonicum to explore the helper T-cell response of patients either at the chronic or advanced stage of the disease.
Xi Wang, Qi Tang, Robert Bergquist, Xiaorong Zhou, Zhiqiang Qin   +4 more
doaj   +1 more source

Galectin-9 contributes to the pathogenesis of atopic dermatitis via T cell immunoglobulin mucin-3

Frontiers in Immunology, 2022
BackgroundAtopic dermatitis (AD), a common type 2 inflammatory disease, is driven by T helper (TH) 2/TH22polarization and cytokines.Galectin-9 (Gal-9), via its receptor T cell immunoglobulin- and mucin-domain-containing molecule-3 (TIM-3), can promote ...
Wenxing Su, Wenxing Su, Wenxing Su, Ji Zhang, Shun Yang, Minhui Tang, Yu Shen, Cuiping Liu, Jiang Ji, Marcus Maurer, Marcus Maurer, Qingqing Jiao   +11 more
doaj   +1 more source