Results 151 to 160 of about 12,071,270 (180)

Irbesartan may relieve renal injury by suppressing Th22 cells chemotaxis and infiltration in Ang II-induced hypertension

International Immunopharmacology, 2020
Angiotensin II (Ang II) as an important pathogenic factor, has been implicated in the pathogenesis of hypertension and associated renal injury, and inhibition of Ang II can reduce renal inflammation and exert renal protective effects.
Xiaozhao Li, Yong Zhong, Ting Meng
exaly   +2 more sources

Pathogenic Th17 and Th22 cells are increased in patients with autoimmune thyroid disorders

Endocrine, 2017
To study the levels of pathogenic and non-pathogenic Th17 and Th22 cells in autoimmune thyroid disorders patients. Although Th17 cells seem to play an important role in the pathogenesis of thyroid autoimmune disorders, the specific subsets of these lymphocytes have not been analyzed in this condition.We assessed the levels of Th17 (pathogenic and non ...
Roberto González-Amaro, MIGUEL Sampedro-Nunez, Ana M Ramos-Levi   +2 more
exaly   +4 more sources

Role of Th22 cells in Helicobacter pylori-related gastritis and peptic ulcer diseases [PDF]

Molecular Biology Reports, 2019
Helicobacter pylori (H. pylori) has been shown to be one of the leading causes of peptic ulcer diseases (PUDs) and gastritis. T helper-22 (Th22) cells and its most important cytokine, interleukin-22 (IL-22) are importantly active in inflammation and ...
A. Sanaii, H. Shirzad, Mehrnoosh Haghighian, G. Rahimian, A. Soltani, M. Shafigh, Kamran Tahmasbi, N. Bagheri   +7 more
semanticscholar   +2 more sources

Response to extracorporeal photopheresis therapy of patients with steroid-refractory/-resistant GvHD is associated with up-regulation of Th22 cells and Tfh cells.

Cytotherapy, 2021
Extracorporeal photopheresis (ECP), a personalized cellular immunotherapy, constitutes a promising treatment for steroid-refractory/-resistant graft-versus-host disease (SR-GvHD), with encouraging clinical response rates.
M. Ni, Lei Wang, Yu Ding, Wenjie Gong, Sanmei Wang, Brigitte Neuber, M. Schubert, T. Sauer, Angela Hückelhoven-Krauss, T. Luft, U. Hegenbart, S. Schönland, V. Eckstein, Jishi Wang, W. Krüger, C. Müller-Tidow, P. Dreger, M. Schmitt, A. Schmitt   +18 more
semanticscholar   +1 more source

Skin-Homing Th2/Th22 Cells in Papuloerythroderma of Ofuji

Dermatology, 2014
Papuloerythroderma of Ofuji (PEO) appears to be a T cell-mediated skin disease; however, the pathogenesis of PEO remains unclear. We report two cases of PEO and examine cytokine production and expression of skin-homing receptors in circulating T cells in the patients.
Yuichi, Teraki, Yumiko, Inoue
openaire   +2 more sources

The Biology and Functions of Th22 Cells

2014
T helper (Th) cells develop from naïve CD4(+) T cells under lineage-specific culture conditions and are nominated by their lineage-specific cytokines. Th22 cells, new players in adoptive immune responses, are identified by the production of interleukin (IL)-22.
Lei, Jia, Changyou, Wu
openaire   +2 more sources

Induction of skin-pathogenic Th22 cells by epicutaneous allergen exposure.

Journal of Dermatological Science, 2017
Atopic dermatitis (AD) is a common inflammatory skin disease with dysfunction of the skin barrier, an abnormal immune response and frequent allergies to environmental antigens like food antigens. Clinical observations suggest that certain diets can influence the course of AD.Here we compared the phenotype of food allergen-specific T cells activated ...
I. Glocova, J. Brück, Julia Geisel, E. Müller-Hermelink, Katja Widmaier, A. Yazdi, M. Röcken, K. Ghoreschi   +7 more
semanticscholar   +3 more sources

An increased proportion of circulating Th22 and Tc22 cells in psoriasis

Cellular Immunology, 2014
Psoriasis is a common dermatosis mediated by T cells. This study investigated the correlation of Th22 cells and Tc22 cells with psoriasis. A total of 30 psoriasis patients and 11 age- and sex-matched healthy controls were recruited for this study. The proportions of circulating Th22 and Tc22 cells, expression of aryl hydrocarbon receptor, and IL-22 ...
Li, Luan, Ying, Ding, Shixin, Han, Zhenying, Zhang, Xiaoming, Liu   +4 more
exaly   +3 more sources

Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis

Journal of Clinical Immunology, 2011
T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. The roles of Th22 cells in the pathophysiology of rheumatoid arthritis (RA) remain unsettled.CD4(+)IFNγ(-)IL17(-)IL-22(+) T cells (Th22 cells), CD4(+)IFNγ(-)IL-22(-)IL17(+) T cells (pure Th17 cells), CD4(+)IL17(+) T cells (Th17 cells), and CD4(+)IFNγ(+) T cells ...
Lei, Zhang, Jian-Min, Li, Xin-Guang, Liu, Dao-Xin, Ma, Nai-Wen, Hu, Yong-Gang, Li, Wei, Li, Yu, Hu, Shuang, Yu, Xun, Qu, Mei-Xiang, Yang, A-Lei, Feng, Guang-Hui, Wang   +12 more
openaire   +2 more sources

Elevated profiles of Th22 cells and correlations with Th17 cells in patients with immune thrombocytopenia

Human Immunology, 2012
T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. However, the role of Th22 cells in the pathophysiology of immune thrombocytopenia (ITP) remains unclear. Th22, Th17 and Th1 cells in both ITP patients and healthy controls were examined by flow cytometry. Plasma interleukin-22 (IL-22) level was measured by enzyme
Yu, Hu, Haiyan, Li, Lei, Zhang, Baozhong, Shan, Xingfang, Xu, Hong, Li, Xinguang, Liu, Shuqian, Xu, Shuang, Yu, Daoxin, Ma, Jun, Peng, Ming, Hou   +11 more
openaire   +2 more sources