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Decreased circulating Th22 and Th17 cells in patients with aplastic anemia
Clinica Chimica Acta, 2015Aplastic anemia (AA) is an immune-mediated disorder and mainly related to active destruction of hematopoietic cells by effector T lymphocytes. T helper (Th) 22 cells characterized as a novel subset of CD4+ T cells participate in the pathogenesis of autoimmune and hematological diseases.
Ting Lu +6 more
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Increased Th22 cells are independently associated with Th17 cells in type 1 diabetes
Endocrine, 2013Type 1 diabetes (T1D) is perceived as an autoimmune disease caused by T cell-mediated destruction of the insulin-producing pancreatic β cells. However, the number of inflammatory T cells in blood, as well as the relative importance of each cell type is unclear. Forty-two patients with T1D and 30 controls were enrolled. Circulating primary CD4(+) or CD8(
Xinyu, Xu +7 more
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The role of IL-22 and Th22 cells in human skin diseases
Journal of Dermatological Science, 2013Interleukin (IL)-22 is a cytokine that is involved in the modulation of tissue responses during inflammation. It is produced by immune cell subsets such as T cells, while the expression of its receptor is restricted to cells of non-hematopoietic origin, particularly epithelial cells.
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Th22 cells in autoimmunity: a review of current knowledge.
European annals of allergy and clinical immunology, 2015Newly identified T helper cell 22 (Th22) is a subset of CD4+ T cells with specific properties apart from other known CD4+ T cell subsets. Th22 is obviously discrete from Th17 and Th1 subsets by production of interleukin (IL)-22 but not IL-17 or IFN-γ, and also with distinguished expression of aryl hydrocarbon receptor (AHR) as the key transcription ...
G, Azizi, R, Yazdani, A, Mirshafiey
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[Change and significance of Th22 cells in patients with aplastic anemia].
Zhonghua yi xue za zhi, 2014To explore the proportion of Th22 cells in peripheral blood of patients with aplastic anemia (AA) and evaluate its significance.From January 2011 to June 2012, a total of 47 AA patients were recruited and divided into 4 groups: severe aplastic anemia (SAA) pre-therapy (group A, n = 11), non-severe aplastic anemia (NSAA) pre-therapy (group B, n = 12 ...
Li-min, Liu +7 more
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Analysis of IL-22 and Th22 Cells by Flow Cytometry in Systemic Lupus Erythematosus.
Methods in molecular biology, 2020Zhuang Ye +5 more
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The role of Th22 cells, from tissue repair to cancer progression
Cytokine, 2022Maryam Rastin +2 more
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