Results 161 to 170 of about 10,640,595 (395)

The cell cycle related rhythms, cells' states correlation and the cancer [PDF]

arXiv, 2015
We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a four dimensional dynamic system. We assume that the cell's decision making property is strongly affected by the
arxiv  

Heterogeneity of helper/inducer T lymphocytes. IV. Stimulation of resting and activated B cells by Th1 and Th2 clones. [PDF]

, 1990
Abul K. Abbas, Sandy S. Urioste, Tucker Collins, W H Boom   +3 more
openalex   +1 more source

Iron Deficiency Impairs Dendritic Cell Development and Function, Compromising Host Anti‐Infection Capacity

Advanced Science, EarlyView.
Iron deficiency reduces monocyte dendritic cell progenitor (MDP) numbers by inhibiting migration and proliferation while promoting apoptosis, subsequently reducing downstream common dendritic cell precursors (CDP) and dendritic cell (DC). Impaired DCs enter the lungs via blood circulation, where reduced antigen presentation impairs T‐cell activation ...
Quanzhong Ren, Xiaotong Xu, Zheng Dong, Jiahuang Qiu, Qing'e Shan, Rui Chen, Yajun Liu, Juan Ma, Sijin Liu   +8 more
wiley   +1 more source

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

PLoS Pathogens, 2015
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known.
Darin L Wiesner, Charles A Specht, Chrono K Lee, Kyle D Smith, Liliane Mukaremera, S Thera Lee, Chun G Lee, Jack A Elias, Judith N Nielsen, David R Boulware, Paul R Bohjanen, Marc K Jenkins, Stuart M Levitz, Kirsten Nielsen   +13 more
doaj   +1 more source

Parasite-antigen driven expansion of IL-5(-) and IL-5(+) Th2 human subpopulations in lymphatic filariasis and their differential dependence on IL-10 and TGFβ.

PLoS Neglected Tropical Diseases, 2014
BackgroundTwo different Th2 subsets have been defined recently on the basis of IL-5 expression - an IL-5(+)Th2 subset and an IL-5(-)Th2 subset in the setting of allergy.
Rajamanickam Anuradha, Parakkal Jovvian George, Luke E Hanna, Vedachalam Chandrasekaran, P Paul Kumaran, Thomas B Nutman, Subash Babu   +6 more
doaj   +1 more source

CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice. [PDF]

, 1992
Ricardo T. Gazzinelli, Masahiko Makino, Sisir K. Chattopadhyay, Clifford M. Snapper, Alan Sher, Ambros W. Hügin, Herbert C. Morse   +6 more
openalex   +1 more source

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

Advanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang, Matthew C. Hill, Mingxing He, Junhao Chen, Zirui Wang, Patrick T. Ellinor, Min Li   +6 more
wiley   +1 more source

Scale‐Up of Human Amniotic Epithelial Cells Through Regulation of Epithelial‐Mesenchymal Plasticity Under Defined Conditions

Advanced Science, Volume 12, Issue 11, March 20, 2025.
Freshly isolated human amniotic epithelial cells (hAECs) from full‐term amniotic membranes include mature epithelial cells as well as cells in a senescent state. During in vitro culture, hAECs undergo epithelial‐mesenchymal transition (EMT) and enter a partial epithelial‐mesenchymal transition (pEMT) state (E/M hybrid) resembling early developmental ...
Wangping Hao, Yi Luo, Jia Tian, Yuefeng Lu, Yangyang Cui, Ying Zhang, Xiao Jin, Hongjuan Ye, Mengqi Lu, Jinjia Song, Weiqing Zhou, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Priming dendritic cells for Th2 polarization: lessons learned from helminths and implications for metabolic disorders

Frontiers in Immunology, 2014
Nearly one quarter of the world’s population is infected with helminth parasites. A common feature of helminth infections is the manifestation of a type 2 immune response, characterized by T helper 2 (Th2) cells that mediate anti-helminth immunity.
Leonie eHussaarts, Maria eYazdanbakhsh, Bruno eGuigas, Bruno eGuigas   +3 more
doaj   +1 more source

Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1.

Proceedings of the National Academy of Sciences of the United States of America, 2000
This study addresses the issue of the effect of immunomodulating therapies in the target organ-the central nervous system (CNS)-in the case of multiple sclerosis.
R. Aharoni, D. Teitelbaum, Orith Leitner, Asher Meshorer, Michael Sela, Ruth Arnon   +5 more
semanticscholar   +1 more source