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The Metabolic Requirements of Th2 Cell Differentiation [PDF]
Upon activation, naïve CD4+ T cells differentiate into a number of specialized T helper (Th) cell subsets. Th2 cells are central players in immunity to helminths and are implicated in mediating the inflammatory pathology associated with allergies.
Julian M. Stark+2 more
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New Insights into HIV Life Cycle, Th1/Th2 Shift during HIV Infection and Preferential Virus Infection of Th2 Cells: Implications of Early HIV Treatment Initiation and Care [PDF]
The theory of immune regulation involves a homeostatic balance between T-helper 1 (Th1) and T-helper 2 (Th2) responses. The Th1 and Th2 theories were introduced in 1986 as a result of studies in mice, whereby T-helper cell subsets were found to direct ...
Joseph Hokello+6 more
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A large body of evidence indicates the existence of functionally polarized CD4+ T-cell responses based on their profile of cytokine secretion. Type 1 T helper (Th1) cells produce interferon-gamma, interleukin (IL)-2, and tumour necrosis factor (TNF)-beta,
S. Romagnani
semanticscholar +4 more sources
Th1 and Th2 cells in autoimmunity [PDF]
P Druet+2 more
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Th2 cells: help for helminths. [PDF]
Richard M. Locksley
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Mercury: god of Th2 cells? [PDF]
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Peter W. Mathieson
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Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response
Th2 immune response is essential for providing protection against pathogens and orchestrating humoral immunity. However, excessive Th2 immune response leads to the pathogenesis of Th2 inflammation diseases, including asthma, allergic rhinitis, and atopic
Guo Liu, Feng Liu
doaj +3 more sources
Objectives: Peripheral blood immune cell profiling of atopic dermatitis patients before and after treatment by single-cell RNA sequencing technique has not been reported.
Xiao-Guang Gu+6 more
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Interleukin-33/ST2: A new signaling pathway in immunity and immunopathology [PDF]
nema
Pavlović Slađana+5 more
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Increased Proportion of Dual-Positive Th2–Th17 Cells Promotes a More Severe Subtype of Asthma
Asthma is a heterogeneous disease, and abnormal activation of T cells is the driving link of asthma’s pathophysiological changes. Dual-positive Th2–Th17 cells, as newly discovered T-helper cells, have the functions of Th2 and Th17 cells and can coproduce
Wenjin Sun+9 more
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