Results 31 to 40 of about 4,912,109 (290)

Epigenetic and Transcriptional Regulation in the Induction, Maintenance, Heterogeneity, and Recall-Response of Effector and Memory Th2 Cells

Frontiers in Immunology, 2018
Antigen-primed T cells respond to restimulation much faster than naïve T cells and form the cellular basis of immunological memory. The formation of memory Th2 cells starts when naïve CD4 T cells are transformed into effector Th2 cells and is completed ...
Atsushi Onodera, Atsushi Onodera, Kota Kokubo, Toshinori Nakayama   +3 more
doaj   +1 more source

Alarming dendritic cells for Th2 induction [PDF]

The Journal of Experimental Medicine, 2008
There is an ever-increasing understanding of the mechanisms by which pathogens such as bacteria, viruses, and protozoa activate dendritic cells (DCs) to drive T helper type 1 (Th1) responses, but we know much less about how these cells elicit Th2 responses.
MacDonald, Andrew S.; id_orcid 0000-0002-5356-1149, Maizels, Rick M.   +1 more
openaire   +5 more sources

Cord blood Vα24-Vβ11 natural killer T cells display a Th2-chemokine receptor profile and cytokine responses [PDF]

, 2011
Background: The fetal immune system is characterized by a Th2 bias but it is unclear how the Th2 predominance is established. Natural killer T (NKT) cells are a rare subset of T cells with immune regulatory functions and are already activated in utero ...
Elfriede Noessner, Krauss-Etschmann, S., Faber Fabienne L., Harner, Susanne, Harner, S., Nadas, Korinna, Leumann-Runge Anke, Leumann-Runge, A., Leumann-Runge, Anke, Susanne Harner, Korinna Nadas, Nadas, K., Joachim Heinrich, Heinrich, Joachim, Fabienne L Faber, Nadas Korinna, Heinrich, J., Noessner Elfriede, Noessner, Elfriede, Anke Leumann-Runge, Schiemann, Matthias, Susanne Krauss-Etschmann, Krauss-Etschmann Susanne, Fabienne L. Faber, Schiemann Matthias, Nößner, E., Faber, Fabienne L., Krauss-Etschmann, Susanne, Schiemann, M., Faber, F.L., Heinrich Joachim, Harner Susanne, Matthias Schiemann, Harner, S;Noessner, E;Nadas, K;Leumann-Runge, A;Schiemann, M;Faber, FL;Heinrich, J;Krauss-Etschmann, S   +33 more
core   +2 more sources

Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen.

PLoS Neglected Tropical Diseases, 2019
T cell-intrinsic regulation, such as anergy, adaptive tolerance and exhaustion, is central to immune regulation. In contrast to Type 1 and Type 17 settings, knowledge of the intrinsic fate and function of Th2 cells in chronic Type 2 immune responses is ...
Johanna A Knipper, Alasdair Ivens, Matthew D Taylor   +2 more
doaj   +1 more source

Mercury: god of Th2 cells? [PDF]

Clinical and Experimental Immunology, 1995
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openaire   +2 more sources

A differential interplay between the expression of Th1/Th2/Treg related cytokine genes in Teladorsagia circumcincta infected DRB1*1101 carrier lambs [PDF]

, 2011
peer-reviewedSubstantial debate exists on whether the immune response between sheep resistant and susceptible to gastrointestinal nematodes can be differentiated into a Th1 and Th2 phenotype.
Barbara Good, Good Barbara, Good, Barbara, Mulcahy, Grace, Sweeney, Torres, Mulcahy Grace, Hassan, Musa, Hanrahan, James P, Sweeney Torres, Grace Mulcahy, Musa Hassan, Hanrahan James P, James P Hanrahan, Hassan Musa, Hanrahan, James P., Torres Sweeney   +15 more
core   +1 more source

The function and origin of the CD4+ T cell in the classical Hodgkin lymphoma microenvironment [PDF]

, 2012
PhDClassical Hodgkin lymphoma (CHL) is a germinal centre B cell malignancy where the bulk of the tumour comprises a non-clonal immune infiltrate enriched for CD4+ T cells.
Greaves, Paul
core   +2 more sources

The Concept of Pathogenic TH2 Cells: Collegium Internationale Allergologicum Update 2021. [PDF]

, 2021
T helper (TH) cells have evolved into distinct subsets that mediate specific immune responses to protect the host against a myriad of infectious and noninfectious challenges.
Bertschi, Nicole L., Schlapbach, Christoph, Bazzini, Cecilia, Cecilia Bazzini, Christoph Schlapbach, Nicole L. Bertschi   +5 more
core   +1 more source

Thymic Stromal Lymphopoietin and Cancer: Th2-Dependent and -Independent Mechanisms

Frontiers in Immunology, 2020
The thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine originally cloned from a murine thymic stromal cell line, and subsequently a human homolog was identified using database search methods.
Maria Pia Protti, Maria Pia Protti, Lucia De Monte, Lucia De Monte   +3 more
doaj   +1 more source

Beyond CCR7: dendritic cell migration in type 2 inflammation

Frontiers in Immunology
Conventional dendritic cells (cDCs) are crucial antigen-presenting cells that initiate and regulate T cell responses, thereby shaping immunity against pathogens, innocuous antigens, tumors, and self-antigens. The migration of cDCs from peripheral tissues
Audrey Meloun, Audrey Meloun, Beatriz León   +2 more
doaj   +1 more source