Results 41 to 50 of about 10,640,595 (395)
Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression. [PDF]
PLoS ONE, 2011 BACKGROUND:Although in vitro IL-4 directs CD4 T cells to produce T helper 2 (Th2)-cytokines, these cytokines can be induced in vivo in the absence of IL-4-signalling.
Karine Serre +10 more
doaj +1 more source
Unveiling Kinematic Structure in the Starburst Heart of NGC 253 [PDF]
, 2020 We investigate the kinematics of ionized gas within the nuclear starburst of NGC 253 with observations of the Brackett $\alpha$ recombination line at 4.05 $\mu$m. The goal is to distinguish motions driven by star-formation feedback from gravitational motions induced by the central mass structure. Using NIRSPEC on Keck II, we obtained 30 spectra through
arxiv +1 more source
CD4+ Th2 cells are directly regulated by IL-10 during allergic airway inflammation
Mucosal Immunology, 2016 Interleukin-10 (IL-10) is an important regulatory cytokine required to control allergy and asthma. IL-10-mediated regulation of T cell-mediated responses was previously thought to occur indirectly via antigen-presenting cells.
SM Coomes +8 more
semanticscholar +1 more source
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. [PDF]
, 2017 MicroRNAs (miRNAs) exert powerful effects on immunity through coordinate regulation of multiple target genes in a wide variety of cells. Type 2 innate lymphoid cells (ILC2s) are tissue sentinel mediators of allergic inflammation.
Ansel, K Mark +7 more
core +2 more sources
A tissue checkpoint for TH2s [PDF]
Nature Reviews Immunology, 2016 A cell-intrinsic checkpoint restricts type 2 cytokine production by ILC2s and TH2 cells at sites of tissue damage.
openaire +3 more sources
Nature Communications, 2018 ST2hi memory-type Th2 cells are identified as a pathogenic subpopulation in eosinophilic airway inflammation. These ST2hi pathogenic Th2 cells produce large amount of IL-5 upon T cell receptor stimulation, but not in response to IL-33 treatment.
Takeshi Yamamoto +13 more
semanticscholar +1 more source
Reconsidering Res Judicata: A Comparative Perspective [PDF]
, 2011 We aimed to prospectively investigate the paternal antigen-induced cytokine secretion by peripheral blood mononuclear cells (PBMCs) in response to hormone treatment in women undergoing in vitro fertilisation (IVF) and to examine the predictive value of ...
Berg, Göran +6 more
core +3 more sources
CD4+ T Cell Plasticity—Th2 Cells Join the Crowd [PDF]
Immunity, 2010 In this issue of Immunity, Hegazy et al. (2010) report that in response to lymphocytic choriomeningitis virus (LCMV) infection, fully differentiated virus-specific Th2 cells can be reprogrammed into GATA-3(+)T-bet(+) cells capable of producing both interleukin-4 and interferon-gamma.
Jinfang Zhu, William E. Paul
openaire +3 more sources
Thymic Stromal Lymphopoietin and Cancer: Th2-Dependent and -Independent Mechanisms
Frontiers in Immunology, 2020 The thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine originally cloned from a murine thymic stromal cell line, and subsequently a human homolog was identified using database search methods.
Maria Pia Protti +3 more
doaj +1 more source
Mucosal Immunology, 2016 Immunity to many human and murine gastrointestinal helminth parasites requires interleukin-4 (IL-4)-directed type 2 helper (TH2) differentiation of CD4+ T cells to elicit type-2 immunity.
Victoria S. Pelly +8 more
semanticscholar +1 more source