Results 211 to 220 of about 71,295 (266)

Heterogeneity of Thalassemia Major

Archives of Pediatrics & Adolescent Medicine, 1963
Previous communications1,2concerning A2hemoglobin in parents of subjects with thalassemia major reported normal levels in a small minority. Fetal hemoglobin percentage was determined in some of these individuals and was noted to be unexpectedly high in all but one.
J A, WOLFF, V G, IGNATOV
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Echocardiographic findings in thalassemia major

Acta Paediatrica, 1994
[No abstract available]
Kilinc Y., Acarturk E., Kumi M., Antmen B., Yilmaz L.   +4 more
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Pancreatic Sonography in Thalassemia Major

Klinische Pädiatrie, 1983
Four patients with thalassemia major and well documented transfusional anamnesis were investigated sonographically. Beside the fibrous reaction of iron overload in the liver the outstanding finding was the grossly increased echogenicity of the normal sized fibrotic pancreas in transfusional hemosiderosis.
R, Erttmann, G, Hausdorf, G, Landbeck
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Cardiac complications in thalassemia major

Annals of the New York Academy of Sciences, 2016
The myocardium is particularly susceptible to complications from iron loading in thalassemia major. In the first years of life, severe anemia leads to high‐output cardiac failure and death if not treated. The necessary supportive blood transfusions create loading of iron that cannot be naturally excreted, and this iron accumulates within tissues ...
Auger, D, Pennell, DJ
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Pulmonary function in thalassemia major

The Journal of Pediatrics, 1987
Pulmonary function tests were evaluated in 28 Chinese patients with beta-thalassemia major receiving regular transfusions and desferoxamine, and in 34 height-matched normal Chinese children. Comparison of lung function using analysis of covariance with reference to standing height showed that patients with thalassemia had a proportional decrease in ...
Fung, K.P., Chow, O.K.W., So, S.Y., Yuen, P.M.B.   +3 more
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Psychosocial implications of Thalassemia Major

Pediatrics International, 2005
Abstract  Background : Many causes including the chronicity of disease, burden of treatment modalities, morbidities, and the expectation of early death resulting from the disease complications, may lead to psychosocial burden in Thalassemia Major (TM) patients.
Aydinok Y., Erermis S., Bukusoglu N., Yilmazi D., Solak U.   +4 more
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Myopathological Findings in Thalassemia Major

European Neurology, 2008
In thalassemia major (TM) one third of patients suffers from muscle wasting, weakness and cramps. Six patients with TM were studied. All had muscle wasting and proximal weakness; serum levels of vitamin E were low (0.6–7.0 µg/dl) while CPK, LDH and aldolase were normal.
Y, Shapira, B, Glick, A, Finsterbush, A, Goldfarb, E, Rosenmann   +4 more
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Cardiovascular MRI in thalassemia major

Annals of the New York Academy of Sciences, 2010
MRI assessment of myocardial iron and function has revolutionized the treatment of thalassemia major patients. While knowledge of somatic iron stores is vital for iron chelation management, it does not adequately monitor cardiac risk. MRI monitoring of cardiac T2* allows preclinical recognition of myocardial iron, stratifies prospective cardiac risk ...
John C, Wood, Leila, Noetzli
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Endocrine Function in Thalassemia Major

The Journal of Clinical Endocrinology & Metabolism, 1968
Abstract Seven patients with thalassemia major, ranging in age from 6½ to 23 yr, were studied. Growth retardation was present in all except the youngest patient. Thyroid and adrenal function was normal. Three patients, however, showed an unexplained increase in the serum protein bound iodine level.
B, Kuo, E, Zaino, M S, Roginsky
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Complications of thalassemia major and their treatment

Expert Review of Hematology, 2011
The life of patients with thalassemia has improved both in duration and in quality in industrialized countries. Complications are still common and include heart disease (heart failure and arrhythmias), chronic liver hepatitis, which can evolve in cirrhosis and, rarely, in hepatocellular carcinoma, endocrine problems (hypogonadism, hypothyroidism ...
BORGNA, Caterina, M. R. Gamberini
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