Results 221 to 230 of about 71,295 (266)
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Renal Enlargement in Thalassemia Major
Radiology, 1971Twenty-four patients with thalassemia major and no urinary tract complaints underwent excretory urography. The kidneys were large bilaterally in 17 patients; 2 other patients had enlargement of the left kidney. The autopsies of 13 patients were reviewed; the kidneys were large in all 13.
H, Grossman +3 more
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Iron Chelation in Thalassemia Major
Clinical Therapeutics, 2015Iron chelation has improved survival and quality of life of patients with thalassemia major. there are currently 3 commercially available iron-chelating drugs with different pharmacokinetic and pharmacodynamic activity. The choice of adequate chelation treatment should be tailored to patient needs and based on up-to-date scientific evidence.A review of
BORGNA, Caterina, Marsella, M.
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Auditory Involvement in Thalassemia Major
Acta Haematologica, 2009The auditory function of 75 children affected by homozygous β°-thalassemia, managed with a low transfusion scheme and treated irregularly with low doses of desferrioxamine, and of 75 controls were examined. In 12 patients a mild bilateral conductive hearing impairment due to bony hypertrophy and/or adenoid hypertrophy was found.
S, De Virgiliis +7 more
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Neutropenia in Patients with Thalassemia Major.
Blood, 2004Abstract Monitoring of the neutrophil count has become an important issue in the management of thalassemia patients after the introduction of the new oral chelator deferiprone, as this chelator has been associated with agranulocytosis and milder neutropenias.
GALANELLO, RENZO, ORIGA, RAFFAELLA
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Growth and Puberty in Thalassemia Major
Journal of Pediatric Endocrinology and Metabolism, 1995Growth and sexual development were evaluated in 54 (29 female, 25 male) patients with beta-thalassemia major aged 2.7-21.3 years (mean 10.4 yr). Mean pretransfusion hemoglobin concentration was 7.8 +/- 0.7 mg/dl. All patients except 6 were on desferrioxamine. Age of starting of therapy was 6.8 +/- 3.9 years.
N, Saka +5 more
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Hepatitis in children with thalassemia major
1992Since thalassemia major patients are transfusion dependent, they are at a particularly high risk of contracting post-transfusion hepatitis. In this study, 36 transfusion-dependent children were followed up for evidence of viral hepatitis. Of 23 with increased ALT levels, 17 were anti-CMV and 12 were anti-HCV positive, 9 were positive for both CMV and ...
G, Nigro +9 more
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Update on Survival in Thalassemia Major
Hemoglobin, 2009Long-term follow-up of cohorts of patients treated in high-income countries has shown a progressive improvement in life expectancy. Myocardial toxicity from iron overload has been the major cause of mortality; however, there has been a substantial decline in cardiac deaths in recent years, related to switching high-risk patients from subcutaneous ...
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Hepcidin and β-thalassemia major
Blood, 2013In this issue of Blood, Pasricha et al evaluated serum hepcidin and its putative pathological suppressor growth differentiation factor-15 (GDF-15) in patients with β-thalassemia major before and after transfusion, in the context of erythropoietic activity and iron loading.
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Home treatment in thalassemia major.
Acta paediatrica Belgica, 1979info:eu-repo/semantics ...
Alexander, Marc, Luyckx, W., Fonfu, P.
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Fertility and Pregnancy in Thalassemia Major
Annals of the New York Academy of Sciences, 2005Abstract: Over the last 15 years, 22 women with thalassemia major have completed 29 pregnancies at the Royal Hospital in London. The major pre‐pregnancy issues, medications, and pregnancy care are reviewed. Experience suggests that, with proper care and guidance, pregnancies among women with thalassemia major are practical and can have successful ...
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