Results 91 to 100 of about 2,702 (213)

Clinical Significance of Diagnostic Images in Beta-Thalassemia

Вестник рентгенологии и радиологии
Thalassemias represent a heterogeneous group of autosomal recessive disorders resulting from reduced synthesis of alpha or beta hemoglobin chains causing structural abnormalities in red blood cells with their premature destruction accompanied by ...
O. V. Teplyakova, E. Z. Eidlina, O. G. Tsvetkova, A. А. Zhilyakov   +3 more
doaj   +1 more source

Global Burden of Sickle Cell Disease: Adequacy of Pain Control as Evidenced by Frequency of Oral Pain Medication Use, Health Outcomes, and Emotional Well‐Being Across Diverse Populations

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Sickle cell disease (SCD) is a chronic genetic disorder causing severe pain, anemia, and systemic complications that negatively affect patients’ physical and mental well‐being. The aim of this global cross‐sectional study was to evaluate the relationship between oral pain medication (OPM) use frequency and health outcomes ...
Akshat Jain, Lisa Roberts, Safiye Sahin
wiley   +1 more source

Liver Cirrhosis and In‐Hospital Outcomes in Patients With Sickle Cell Crises

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Sickle cell disease (SCD) is a hematologic disorder characterized by chronic hemolysis, vaso‐occlusion, and end‐organ dysfunction. Patients with SCD may experience acute episodes known as sickle cell crises, which are sudden, severe complications typically involving pain or organ‐specific manifestations resulting from vaso ...
Shakirat Gold‐Olufadi, Kayode Ogunniyi, Adeleke Oluwaseun Dorcas, Bukola Florence Tabiti, Dosbai Saparov, Chiamaka Nwachukwu, Henry Becerra, Sravani Bhavanam, Shrestha Neharika, John Ogedegbe, Ifeanyi Nnamdi Uche, Jen Chin Wang, Chinemerem Martlin Emeasoba, Dania Jaamour, Toluwalase Awoyemi   +14 more
wiley   +1 more source

Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies

Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley   +1 more source

Effect of Tonsillar Retractor on Intracranial and Intraocular Pressure in Children Undergoing Adenotonsillectomy Surgeries

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
The effect of tonsillar retractor placement on IOP and ONSD values. ABSTRACT Objectives The tonsillar retractor used during adenotonsillectomy, one of the most common pediatric surgeries, may increase sympathetic activity. This study aimed to evaluate the effect of tonsillar retractor insertion on intracranial pressure (ICP) and intraocular pressure ...
Ayse Bozkurt Oflaz, Meltem Isık, Merih Onal, Mete Kaan Bozkurt, Ozkan Onal, Banu Bozkurt   +5 more
wiley   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 295-304, April 2026.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

ACMG/AMP‐Based Variant Classification of a Novel HBA2 Variant (HBA2: C.297del, Hb Taiping) in Compound Heterozygosity With Hb Adana (HBA2:C.179G>A) Causing Non‐Deletional Hb H Disease

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 458-465, April 2026.
ABSTRACT Background Accurate classification of novel globin gene variants is critical for the diagnosis and management of thalassaemia. The adaptation of ACMG/AMP guidelines for globin genes represents an important step toward standardising variant interpretation and enhancing clinical utility in the field.
Norafiza Mohd Yasin, Suguna Somasundram, Syahzuwan Hassan, Nur Aisyah Aziz, Faidatul Syazlin Abdul Hamid, Ezzanie Suffya Zulkefli, Nor Nazuha Mohamad, Chin Ming Lee, Mohd Nazif Darawi, Thessalia Papasavva, Coralea Stephanou, Petros Kountouris, Sandra J. G. Arkesteijn, Tamara Koopman, Cornelis L. Harteveld   +14 more
wiley   +1 more source

A Case of IDH‐Mutant Astrocytoma Harboring an IDH2 R172_H173delinsSN Variant

Neuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT IDH‐mutant gliomas most commonly harbor the canonical IDH1 p.R132H mutation, followed by less common mutations involving IDH1 p.R132 or IDH2 p.R172 codons. We present a case of a 32‐year‐old male found to have a left temporal brain tumor with regional enhancement on brain MRI, for which he underwent resection.
Thomas Auen, Jie Chen, Nicole Shonka, Sahara Cathcart   +3 more
wiley   +1 more source

Antimicrobial and Cytotoxic Activities of Biogenic Nanoparticles Produced by Cyanobacteria

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
The article reviews the green synthesis of biogenic nanoparticles produced by cyanobacteria, highlighting their antimicrobial and cytotoxic properties. These nanoparticles, formed intra‐ or extracellularly, show activity against Gram‐positive and Gram‐negative bacteria as well as fungi and can induce apoptosis in tumor cells.
Laíne Santos Ribeiro, Rhuana Valdetário Médice, Janaína Morone Bavini, Camila Manoel Crnkovic, Samuel Cavalcante do Amaral   +4 more
wiley   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, James M. Stark, Ricardo A. Mosquera, Ashwin P. Patel, Aravind Yadav   +9 more
wiley   +1 more source