Results 101 to 110 of about 4,160 (239)

A Concise Review on the Frequency, Major Risk Factors and Surveillance of Hepatocellular Carcinoma (HCC) in beta-Thalassemias: Past, Present and Future Perspectives and the ICET-A Experience

, 2020
Due to the recent alarming increase in the incidence of hepatocellular carcinoma (HCC) in thalassemias, the present report reviews briefly the frequency, the major risk factors, and the surveillance of HCC in beta-thalassemias.
Kattamis, Antonis, Maria Concetta, Messina, Di Maio, Raiola, Giuseppe, Giuseppe, Kaleva, Valeria, Canatan, Duran, Skafida, Myrto, De Sanctis, Vincenzo, Alansary, Niveen, Christou, Soteroula, Karimi, Mehran, Kattamis, Christos, Galati, Campisi, Saveria, Al Jaouni, Soad, Kakkar, Shruti, Mariannis, Demetris, Daar, Shahina, Soliman, Ashraf T., Yassin, Mohamed A., Salvatore   +22 more
core   +1 more source

Expanding the Utility of Exome Sequencing in Preventive and Population Genetics

American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2433-2442, November 2026.
ABSTRACT Carrier screening is a long‐standing genetic testing process offered to at‐risk couples, with or without a family history, who might have pregnancies affected by an autosomal recessive (AR) or X‐linked (XL) disorder. A total of 276 unrelated individuals, initially referred for rare disorder screening by clinicians, were enrolled in this study ...
Charilaos Kostoulas, Athanasia Sesse, Ioanna Bouba, Robert Najdecki, Spyridon Konitsiotis, Sofia Markoula, Ioannis Georgiou   +6 more
wiley   +1 more source

Does Molecularly Guided Therapy Change the Surgical Goals of Glioma Resection?

Brain and Behavior, Volume 16, Issue 11, November 2026.
ABSTRACT Purpose For more than 20 years, the goal of glioma surgery has been to remove as much tumor as possible without compromising patient safety. Many retrospective studies support that greater extent of resection is often associated with longer survival. However, three recent developments have challenged this traditional approach.
Naeem Ul Haq, Sardar Umer Irshad, Irfan Ullah, Sardar Remsha Irshad, Shah Mir, Muhammad Shaheer Khan, Ali Mumtaz, Malik Ahsan Jamal, Jahan Mubariz   +8 more
wiley   +1 more source

Deletional alpha thalassemias in Cukurova

, 1999
Purpose: The production of the ?-chains are reduced or abolished in ?-thalassemia. The ?-thalassemia-2 and ?-thalassemia-1 are common in Southeast and Mediterranean countries.
Yuregir G.T., Curuk M.A., Aksoy K., Polat G.   +3 more
core   +1 more source

Therapeutic Relevance of Inducing Autophagy in β-Thalassemia

Cells
The β-thalassemias are inherited genetic disorders affecting the hematopoietic system. In β-thalassemias, more than 350 mutations of the adult β-globin gene cause the low or absent production of adult hemoglobin (HbA).
Roberto Gambari, Alessia Finotti
doaj   +1 more source

Phenazopyridine‐Induced Sulfhemoglobinemia

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Prolonged phenazopyridine exposure can cause sulfhemoglobinemia and suspected oxidative hemolytic anemia. Persistent low pulse oximetry readings with indeterminate co‐oximetry warrant laboratory consultation. Management requires withdrawal of the offending drug and supportive care; methylene blue does not reverse sulfhemoglobinemia.
Waldemar Irizarry, Ashton Taylor, Amaya Arora, Astha Guliani   +3 more
wiley   +1 more source

Reasons of Unknown HPLC Peaks during Hemoglobin Analysis for Patients with Beta Thalassemias

, 2014
Beta-thalassemias (β-thal) are inherited quantitative disorders of haemoglobin (Hb) leading to underproduction of the beta globin chains of hemoglobin.
Uday Younis, Hussein, Ahmed Ghazi, Faisal   +1 more
core   +1 more source

Frequency of Sensory Neural Hearing Loss in Major Beta-Thalassemias in Southern Iran [PDF]

, 2011
Objective: The thalassemias are among the most common genetic disorders worldwide, occurring more frequently in the Mediterranean region. The aim of this study was to determined frequency of sensory-neural hearing loss in major β- thalassemias ...
Faramarzi, Abolhassan, Karimi, Mehran, Shishegar, Mahmoud, Heydari, Seyed-Taghi, Kaviani, Masoud   +4 more
core   +1 more source

The Primary Reasons People Participate in Maternal‐Fetal Phase I Clinical Trials Are Psychosocial

Ethics &Human Research, Volume 48, Issue 6, Page 20-31, November–December 2026.
ABSTRACT Recent critiques of ethical guidance for maternal‐fetal therapy clinical trials has highlighted the need to weigh maternal, fetal, and societal interests, respectively, while deprioritizing psychosocial reasons for participation. Psychosocial reasons refer to the psychological and social influences on study participants’ decisions, and they ...
Julia E. H. Brown, Leslie S. Riddle, Emma Canepa, Billie Lianoglou, Dawn Gano, Teresa N. Sparks, Jodi Halpern   +6 more
wiley   +1 more source

Demographic and Nutritional Profile of Thalassemia Carrier and Non‐Carrier Young Children in Bangladesh: A Comparative Study

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
The study assessed the demographic and nutritional profiles of children aged 2–5 years with and without thalassemia carrier status in Belkuchi, Sirajganj, Bangladesh. Thalassemia carrier children had significantly lower height‐for‐age z‐scores (HAZ), indicating poorer linear growth.
Sabuktagin Rahman, Farhana Rinky, Santhia Ireen, Faruk Ahmed   +3 more
wiley   +1 more source