Results 111 to 120 of about 5,799 (244)
Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India [PDF]
, 2012 Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a
Banerjee, A +6 more
core +1 more source
Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation
The FEBS Journal, EarlyView.This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley +1 more source
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Role of malnutrition and parasite infections in the spatial variation in children’s anaemia risk in Northern Angola [PDF]
, 2012 Anaemia has a significant impact on child development and mortality and is a severe public health problem in most countries in sub-Saharan Africa.
Clements, A. C. +5 more
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova +2 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Background Accurate classification of novel globin gene variants is critical for the diagnosis and management of thalassaemia. The adaptation of ACMG/AMP guidelines for globin genes represents an important step toward standardising variant interpretation and enhancing clinical utility in the field.
Norafiza Mohd Yasin +14 more
wiley +1 more source
Transition together: a study of pediatric patients with sickle cell disease as they transition to adult health care [PDF]
, 2015 Introduction: Improvement in medical care for sickle cell patients, translating into improvement in survival, has created the need for an active and intentional process of transition from pediatric to adult oriented health care.
Musgrove, Lauren E
core
Haematologica, 1995 Thalassemia intermedia is a clinical definition applied to patients whose clinical phenotype is milder than that of thalassemia major. Criteria used to define thalassemia intermedia including age at presentation, hemoglobin or fetal hemoglobin levels and transfusion independence, are unsatisfactory. The possibility of typing the molecular defect allows
C. Camaschella, M.D. Cappellini
openaire +2 more sources