Results 91 to 100 of about 47,030 (243)

Treatment of pyoderma gangrenosum with thalidomide in a myelodysplastic syndrome case

International Medical Case Reports Journal, 2016
Umit Yavuz Malkan, Gursel Gunes, Eylem Eliacik, Ibrahim Celalettin Haznedaroglu Department of Hematology, School of Medicine, Hacettepe University, Ankara, Turkey Abstract: Thalidomide may be used as a treatment option for pyoderma gangrenosum (PG) and ...
Malkan UY, Gunes G, Eliacik E, Haznedaroglu IC   +3 more
doaj  

Misinformation and women's health: Rebuilding trust in evidence‐based care

International Journal of Gynecology &Obstetrics, EarlyView.
Zainab Al‐Jawahiri
wiley   +1 more source

Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth, Joseph F. Merola, Richard Furie, Kenneth Kalunian, Ronald F. van Vollenhoven, Juanita Romero‐Diaz, Qianyun Li, Weihong Yang, Catherine Barbey   +8 more
wiley   +1 more source

Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma

Haematologica, 2010
Background Thalidomide maintenance therapy after stem cell transplantation resulted in increased progression-free survival and overall survival in a few trials, but its role in non-transplant eligible patients with multiple myeloma remains unclear.
Heinz Ludwig, Zdenek Adam, Elena Tóthová, Roman Hajek, Boris Labar, Miklós Egyed, Ivan Spicka, Heinz Gisslinger, Johannes Drach, Ingrid Kuhn, Axel Hinke, Niklas Zojer   +11 more
doaj   +1 more source

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

Journal of Experimental Medicine, 1991
Thalidomide selectively inhibits the production of human monocyte tumor necrosis factor alpha (TNF-alpha) when these cells are triggered with lipopolysaccharide and other agonists in culture. 40% inhibition occurs at the clinically achievable dose of the
E. Sampaio, E. Sarno, R. Galilly, Z. Cohn, G. Kaplan   +4 more
semanticscholar   +1 more source

Legal mobilization and anti‐fluoridation campaigning in post‐war Britain

Journal of Law and Society, EarlyView.
Abstract The fluoridation of public water supplies to improve dental health is often cited as an example of an ‘intractable controversy’ in public health, reflecting deeply held principles about rights and the public sphere. This article examines legal mobilization to prevent fluoridation in Britain, from the first pilot studies in the mid‐1950s ...
JANET WESTON
wiley   +1 more source

Thalidomide Effects in Patients with Hereditary Hemorrhagic Telangiectasia During Therapeutic Treatment and in Fli-EGFP Transgenic Zebrafish Model

Chinese Medical Journal, 2015
Background: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by recurrent epistaxis, mucocutaneous telangiectasia, and arteriovenous malformations.
Hong-Ling Peng, Yi-Fang Yi, Shun-Ke Zhou, Si-Si Xie, Guang-Sen Zhang   +4 more
doaj   +1 more source

KRAS Footprints in the Skin: Leveraging Targeted Therapy for Unresectable Intra‐Cerebral AVM

Pediatric Dermatology, EarlyView.
ABSTRACT A 15‐year‐old female with a longstanding, unresectable intracerebral arteriovenous malformation (AVM) involving the bilateral thalami and basal ganglia presented with progressive neurologic decline. Given the inaccessibility of the intracranial lesion, a lipomatous scalp nodule overlying the AVM was biopsied for molecular testing and revealed ...
Donglin Zhang, Jennifer M. Kwon, Beverly Aagaard‐Kienitz, Susan L. Rebsamen, Sarah E. Mc Dermott, Lisa M. Arkin   +5 more
wiley   +1 more source

Drivers of Noncompliance With Vaccine Mandates—The Interplay Between Distrust, Rationality, Morality, and Social Motivation

Regulation &Governance, EarlyView.
ABSTRACT COVID‐19 amplified the issue of public resistance to government vaccination programs. Little attention has focused on people's moral reasons for noncompliance, which differ from—but often build upon—the epistemic claims they make about vaccine safety and efficacy, disease severity, and the trustworthiness of government. This study explores the
Katie Attwell, Hang Duong, Amy Morris, Leah Roberts, Mark Navin   +4 more
wiley   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

Transplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez, Carla Niveyro, Pedro Andrés Villalba Apestegui, Victoria Isabel Martin, Lucila María Compañy Kec, María Cynthia Tomasino, Mariana del Carmen del Marull, Haydee Ingrid Bernard, Claudia Patricia Lorena Fernández, Flavia Marcela Pelech, Maria Fernanda Tosin, María Fernanda González‐Hobecker, Karen Beatrice Duranona, Angela Daiana Jara, Justus Cornely, Oliver A. Cornely, Jon Salmanton‐García   +16 more
wiley   +1 more source