Results 91 to 100 of about 67,878 (296)

Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth, Joseph F. Merola, Richard Furie, Kenneth Kalunian, Ronald F. van Vollenhoven, Juanita Romero‐Diaz, Qianyun Li, Weihong Yang, Catherine Barbey   +8 more
wiley   +1 more source

The efficacy and tolerability of bortezomib, thalidomide, and dexamethasone induction therapy with a thalidomide dose step‐up strategy in patients with newly diagnosed multiple myeloma: A prospective observational study

Cancer Reports
Background Thalidomide‐containing regimens cause adverse events (AEs) that may require a reduction in treatment intensity or even treatment discontinuation in patients with multiple myeloma. As thalidomide toxicity is dose‐dependent, identifying the most
Po‐Wei Liao, Hsueh‐Ju Lu, Tsung‐Chih Chen, Hsin‐Chen Lin, Yu‐Hsuan Shih, Chieh‐Lin Jerry Teng   +5 more
doaj   +1 more source

Thalidomide-induced Bradycardia in an Old Man

International Journal of Gerontology, 2010
We presented a case of an 82-year-old man who had classic Kaposi sarcoma. He took thalidomide 100 mg twice daily for 23 days, and then he felt light-headedness and visited our emergency department.
Ching-Hsueh Tseng, Yu-Jang Su, Yen-Chun Lai   +2 more
doaj   +1 more source

KRAS Footprints in the Skin: Leveraging Targeted Therapy for Unresectable Intra‐Cerebral AVM

Pediatric Dermatology, EarlyView.
ABSTRACT A 15‐year‐old female with a longstanding, unresectable intracerebral arteriovenous malformation (AVM) involving the bilateral thalami and basal ganglia presented with progressive neurologic decline. Given the inaccessibility of the intracranial lesion, a lipomatous scalp nodule overlying the AVM was biopsied for molecular testing and revealed ...
Donglin Zhang, Jennifer M. Kwon, Beverly Aagaard‐Kienitz, Susan L. Rebsamen, Sarah E. Mc Dermott, Lisa M. Arkin   +5 more
wiley   +1 more source

Thalidomide-induced bronchiolitis obliterans organizing pneumonia in a patient with multiple myeloma

Saudi Journal of Kidney Diseases and Transplantation, 2019
Thalidomide, which is an angiogenesis inhibitor and immunomodulator that reduces tumor necrosis factor-alpha, has regained value in the treatment of multiple myeloma. Serious pulmonary complications due to thalidomide use remain relatively uncommon.
Zohra El Ati, Rais Lamia, Jouda Cherif, Hela Jbali, Lilia Ben Fatma, Ikram Mami, Rania Khedher, Wided Smaoui, Madiha Krid, Fethi Ben Hamida, Soumaya Beji, Mohamed Karim Zouaghi   +11 more
doaj   +1 more source

Drivers of Noncompliance With Vaccine Mandates—The Interplay Between Distrust, Rationality, Morality, and Social Motivation

Regulation &Governance, EarlyView.
ABSTRACT COVID‐19 amplified the issue of public resistance to government vaccination programs. Little attention has focused on people's moral reasons for noncompliance, which differ from—but often build upon—the epistemic claims they make about vaccine safety and efficacy, disease severity, and the trustworthiness of government. This study explores the
Katie Attwell, Hang Duong, Amy Morris, Leah Roberts, Mark Navin   +4 more
wiley   +1 more source

Systemic Mycobacterium avium subspecies paratuberculosis infection in sheep : a thesis presented in the fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Publications removed from thesis due to copyright reasons: Smith, S. L., West, D. M., Wilson, P. R., de Lisle, G. W., Collett, M. G., Heuer, C., & Chambers, J. P. (2011). Detection of Mycobacterium avium subsp.
Smith
core  

Misinformation and women's health: Rebuilding trust in evidence‐based care

International Journal of Gynecology &Obstetrics, EarlyView.
Zainab Al‐Jawahiri
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Codes of Ethics in Research and Experimentation in Man [PDF]

, 1973
Professor Liley\u27s most notable contribution to medicine was the introduction of intrauterine fetal blood transfusion in the management of Rh sensitization. His work has had worldwide recognition.
Liley, A. W.
core   +1 more source