Results 101 to 110 of about 47,030 (243)
Transfusion, EarlyView.Abstract Background High‐dose chemotherapy followed by autologous stem cell transplantation (ASCT) remains the standard of care for fit patients with newly diagnosed multiple myeloma (MM). The increasing use of CD38 antibody‐based quadruplet induction regimens such as daratumumab‐VTd (Dara‐VTd) has raised concerns regarding impaired stem cell ...
Maximilian Alexander Röhnert +13 more
wiley +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, EarlyView.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.ABSTRACT This study aimed to evaluate the risk of major congenital malformations (MCMs) associated with first‐trimester exposure to antipsychotics, using a large claims database in Japan. This retrospective cohort study was based on data from a large claims database in Japan. We used a large claims database from 2010 to 2019.
Ryo Obara +16 more
wiley +1 more source
Antitumor activity of thalidomide in refractory multiple myeloma.
New England Journal of Medicine, 1999 S. Singhal +13 more
semanticscholar +1 more source
Self‐Immolative Systems in Diagnostic and Therapeutic Applications
ChemMedChem, Volume 21, Issue 5, 13 March 2026.Self‐Immolative Systems enable the precise, residue‐free release of active molecules, drugs, probes, or sensors, via cyclization or elimination, triggered by specific stimuli. Their versatility drives advances in drug delivery, diagnostics, nanotechnology, materials chemistry, and biosensing, offering chemists control over molecular activation and ...
Windbedema Prisca Ouédraogo +2 more
wiley +1 more source
Aggregate, Volume 7, Issue 3, March 2026.An Axial‐Chiral Vertex Integration (ACVI) strategy is introduced to convert a non‐chiral Pd6L4 metal–organic cage into a chiral Pd4L2 cage, achieving exceptionally high binding affinities up to 109 M−1, enantioselectivity (up to 9.2), and efficient chiral induction for encapsulated achiral dyes.
Haiting Di +11 more
wiley +1 more source
Extramedullary Disease—Achilles Heel in Myeloma?
American Journal of Hematology, Volume 101, Issue 3, Page 521-536, March 2026.ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar +7 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT Aim Tumor flare reaction (TFR) is characterized by an increase in tumor size during immunotherapy, often resembling disease progression. This study explores the relationship between anti‐tumor drugs and tumor flare reaction (TFR) through the FAERS database to assist clinicians in better patient management.
Wei Wang +7 more
wiley +1 more source
Thalidomide is an inhibitor of angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America, 1994 R. D'Amato +3 more
semanticscholar +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT Background The level of measurable residual disease (MRD) is one of the most important features correlating depths of response and long‐term outcomes in multiple myeloma (MM) and MRD evaluation is currently the gold standard tool for assessing treatment response.
Stefania Oliva +37 more
wiley +1 more source