Results 101 to 110 of about 67,878 (296)
ABSTRACT Background and Aims Bortezomib‐induced peripheral neuropathy (BIPN) remains a common treatment side effect in patients with multiple myeloma (MM). Data from rodent models indicate a role of proinflammatory cytokines in BIPN pathophysiology, making them potential therapeutic targets.
Nadine Cebulla +18 more
wiley +1 more source
Machine learning methods for predicting adverse drug events: A systematic review
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo +8 more
wiley +1 more source
Thalidomide and its analogues in prostate cancer therapy: A scientific update [PDF]
Carlton R. Cooper +3 more
openalex +1 more source
ABSTRACT This case report highlights that Langerhans cell histiocytosis should be suspected in the differential diagnosis for children who exhibit failure to thrive, diabetes insipidus, and skin lesions. Early recognition and timely management are crucial for preventing irreversible hypothalamic–pituitary damage and improving outcomes.
Kidus Geabriel Yohannes +3 more
wiley +1 more source
Treatment of pyoderma gangrenosum with thalidomide in a myelodysplastic syndrome case
Umit Yavuz Malkan, Gursel Gunes, Eylem Eliacik, Ibrahim Celalettin Haznedaroglu Department of Hematology, School of Medicine, Hacettepe University, Ankara, Turkey Abstract: Thalidomide may be used as a treatment option for pyoderma gangrenosum (PG) and ...
Malkan UY +3 more
doaj
The Adversary Within (excerpts) [PDF]
Editorial Note: Largely because the public shrinks at the sight and thought of malformed babies, the recent case concerned with the use of thalidomide has, nonetheless, served to bring before the public the need for proof of safety before new drugs are ...
Taylor, Fred M.
core +1 more source
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is an immune disorder causing excessive inflammation and tissue damage. Lymphoma, especially T‐cell lymphoma, is the most common cause of HLH, while Multiple Myeloma (MM) is rarely associated. We present a 61‐year‐old man with spiking fevers, fatigue, and unintentional weight loss. The HLH was driven by
Carla Romagnoli +6 more
wiley +1 more source
Thalidomide: Drug of horror and last resort. A review. Part 2: Actions, mechanisms of actions and therapeutic uses of thalidomide [PDF]
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenThe story of thalidomide to 1964 or thereabout is the topic of Part 1 of this review.
Þorkell Jóhannesson
core
Severe increase in creatinine with hypocalcaemia in thalidomide‐treated myeloma patients receiving zoledronic acid infusions [PDF]
Stephen G. Jones +3 more
openalex +1 more source

