Results 111 to 120 of about 67,878 (296)
Antimetastatic effects of thalidomide by inducing the functional maturation of peripheral natural killer cells [PDF]
, 2020 Kiho Miyazato +2 more
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eJHaem, Volume 7, Issue 1, February 2026.ABSTRACT Background Myeloma bone disease (MBD) is a devastating complication of multiple myeloma (MM) and a primary cause of disability in affected patients. Its pathogenesis is driven by an imbalance in bone remodeling, largely attributed to the overexpression of C‐C motif chemokine ligand 3 (CCL3). While both bortezomib and statins have been reported
Fujun Qu +6 more
wiley +1 more source
Erythema Nodosum Leprosum and Thalidomide: How Effective?
, 2023 Siham Boularbah
openalex +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Trends and predictors of women's risk perception about medications that may cause birth defects [PDF]
, 2019 The purpose of this study was to evaluate the proportion of women who reported perception of medications as a risk for birth defects, whether perceptions have changed over time, and identify socioeconomic and medical factors that are independent ...
Samuelson, Mark
core
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.ABSTRACT This study demonstrates the application of a model based meta analysis (MBMA) framework to characterize the safety and efficacy profiles of therapies in relapsed and refractory multiple myeloma (RRMM). Published clinical trial data were analyzed to evaluate the incidence of Grade ≥ 3 neutropenia and overall response rate (ORR), providing a ...
Zeel Shah +8 more
wiley +1 more source
Why Do We Worry about Trace Poisons? [PDF]
, 1996 Dr. Mazur relates how protests by the political left against nuclear tests and by the political right against fluoridation set the stage for Silent Spring to move the public toward being concerned about latent ...
Mazur, Allan
core +1 more source
Creating the Poor Law Legacy: Institutional Care for Older People Before the Welfare State
, 2012 Why, despite the universalist aspiration of the British welfare state, was institutional care for poor older people so frequently condemned as inferior?
Gorsky, Martin
core +1 more source
Comparison of Two Therapeutic Regimes, Lenalidomide with Dexamethasone and Thalidomide with Dexamethasone, in the Treatment of Multiple Myeloma at a Tertiary Care Hospital in India [PDF]
, 2015 Nithin Sashidharan
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Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.Proteolysis‐targeting Chimeras (PROTACs) ermöglichen die gezielte Degradation bislang als „undruggable“ geltende Proteine über das zelluläre Ubiquitin–Proteasom‐System. In dieser Studie identifizieren Schäfer et al. thiazolbasierte niedermolekulare Liganden, die allosterisch an die Zinkfinger‐Domäne der Ubiquitin‐spezifischen Protease 39 (USP39) binden
Daniel Schäfer +11 more
wiley +1 more source