Results 61 to 70 of about 149,069 (251)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Critical analysis of derivative dispersion relations at high energies [PDF]

, 2003
We discuss some formal and fundamental aspects related with the replacement of integral dispersion relations by derivative forms, and their practical uses in high energy elastic hadron scattering, in particular $pp$ and $\bar{p}p$ scattering.
Abramowitz, Amaldi, Augier, Bertini, Block, Bourrely, Brozan, Bujak, Collins, Covolan, Cudell, Cudell, Cudell, Cudell, Cudell, Cudell, Cudell, Donnachie, Donnachie, Donnachie, Donnachie, Eden, Eden, Eichmann, Fischer, Fischer, Fischer, Fischer, Goldberger, Gradshteyn, Gribov, Gribov, Hagiwara, Heidrich, Höhler, Jackson, Kang, Kang, Kluit, Kolář, Kolář, Lukaszuk, Luna, Martin, Martini, Martynov, Menon, Nussenzveig, Sidhu, Sukhatme, Söding, Vrkoč, Ávila, Ávila, Ávila, Ávila   +55 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Evolution and challenges of DDR: A policy review through the prism of Colombia's DDR experience

Heliyon
Disarmament, demobilization, and reintegration (DDR) processes have undergone significant evolution in recent decades, reflecting the complex dynamics of the transition from conflict to peace. This paper presents a comparative analysis of three generations of DDR processes, illustrating the shift from a primarily security-focused approach to a ...
Rodríguez-Castellón, José Miguel, Justus Liebig University Giessen   +1 more
openaire   +4 more sources

Actionable loss of SLF2 drives B‐cell lymphomagenesis and impairs the DNA damage response

EMBO Molecular Medicine, 2023
The DNA damage response (DDR) acts as a barrier to malignant transformation and is often impaired during tumorigenesis. Exploiting the impaired DDR can be a promising therapeutic strategy; however, the mechanisms of inactivation and corresponding ...
Le Zhang, Matthias Wirth, Upayan Patra, Jacob Stroh, Konstandina Isaakidis, Leonie Rieger, Susanne Kossatz, Maja Milanovic, Chuanbing Zang, Uta Demel, Jan Keiten‐Schmitz, Kristina Wagner, Katja Steiger, Roland Rad, Florian Bassermann, Stefan Müller, Ulrich Keller, Markus Schick   +17 more
doaj   +1 more source

Cell Death Response to DNA Damage. [PDF]

, 2019
The cell death response to DNA damage is discussed in this Perspectives piece with cancer as the backdrop because DNA damaging agents (DDA) are widely used to treat cancer.
Wang, Jean YJ
core   +1 more source

Representation of Integral Dispersion Relations by Local Forms

, 2008
The representation of the usual integral dispersion relations (IDR) of scattering theory through series of derivatives of the amplitudes is discussed, extended, simplified, and confirmed as mathematical identities.
Ferreira, Erasmo, Sesma, Javier
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The DDRS as re3data use case

, 2020
The DDRS - or Data Deposit Recommendation Service - recommends research data repositories to humanities researchers searching for deposit services for their research data, which comply to criteria such as PIDs, funders’ requirements, disciplinary scope or language preferences.
Buddenbohm, Stefan, Moranville, Yoann
openaire   +1 more source

The Effect of Random Surface Inhomogeneities on Microresonator Spectral Properties: Theory and Modeling at Millimeter Wave Range

, 2008
The influence of random surface inhomogeneities on spectral properties of open microresonators is studied both theoretically and experimentally. To solve the equations governing the dynamics of electromagnetic fields the method of eigen-mode separation ...
A. G. Voronovich, A. N. Kolmogorov, E. M. Ganapolskii, F. G. Bass, J. A. Ogilvy, J. R. Taylor, L. A. Vainshtein, Lord Rayleigh, R. Newton, T. Kato, Yu. V. Tarasov, Z. E. Eremenko   +11 more
core   +1 more source