Results 71 to 80 of about 173,239 (326)
The Astrophysical JournalMilky Way analogs (MWAs) have long been studied by astronomers to place our Galaxy within an extragalactic context. With the power of cosmological simulations, we are now able to not only characterize MWAs today, but also watch as they evolve through ...
Alicia M. Savelli +4 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Minimum-entropy Constraints on Galactic Potentials
The Astrophysical JournalA tracer sample in a gravitational potential, starting from a generic initial condition, phase-mixes toward a stationary state. This evolution is accompanied by an entropy increase, and the final state is characterized by a distribution function (DF ...
Leandro Beraldo e Silva +5 more
doaj +1 more source
The milky way total mass profile as inferred from Gaia DR2 [PDF]
Monthly notices of the Royal Astronomical Society, 2019 We determine the Milky Way (MW) mass profile inferred from fitting physically motivated models to the Gaia DR2 Galactic rotation curve and other data.
Marius Cautun +9 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Synthetic Gaia DR3 Surveys from the FIRE Cosmological Simulations of Milky Way-mass Galaxies
The Astrophysical JournalThe third data release (DR3) of Gaia has provided a fivefold increase in the number of radial velocity measurements of stars, as well as a stark improvement in parallax and proper motion measurements.
Tri Nguyen +6 more
doaj +1 more source
The origin of the Milky Way globular clusters [PDF]
, 2016 We present a cosmological zoom-in simulation of a Milky Way-like galaxy used to explore the formation and evolution of star clusters. We investigate in particular the origin of the bimodality observed in the colour and metallicity of globular clusters ...
Agertz, Oscar +2 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model
The Astrophysical JournalThis work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj +1 more source
Simulating the Milky Way is hard
EPJ Web of Conferences, 2012 The formation of the Milky Way in the currently accepted concordance cosmology presents a couple of pitfalls. Mostly, these involve the much reported overcooling problem.
Stinson G., Brook C.
doaj +1 more source