Results 51 to 60 of about 3,781 (264)

Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2015
Morphinan alkaloids are the most powerful narcotic analgesics currently used to treat moderate to severe and chronic pain. The feasibility of morphinan synthesis in recombinant Saccharomyces cerevisiae starting from the precursor (R,S)-norlaudanosoline ...
Elena Fossati, Lauren Narcross, Andrew Ekins, Jean-Pierre Falgueyret, Vincent J J Martin   +4 more
doaj   +1 more source

Development of a novel biocatalytic process to produce codeine from thebaine [PDF]

, 2023
Mohammad Ali Ghazjahanian, Mohammad Ali Ghazjahanian   +1 more
openalex   +1 more source

Protection of naringenin chalcone by a pathogenesis‐related 10 protein promotes flavonoid biosynthesis in Marchantia polymorpha

New Phytologist, Volume 247, Issue 1, Page 233-248, July 2025.
Summary Pathogenesis‐related (PR) proteins are diverse stress‐ or pathogen‐induced proteins. Some are associated with specialised metabolism, including proposed functions for anthocyanin biosynthesis. However, data are limited to a few angiosperm species, and the mode(s) of action are uncertain.
Yanfei Zhou, Cyril Hamiaux, Christelle M. Andre, Janine M. Cooney, Kathy E. Schwinn, John W. van Klink, John L. Bowman, Kevin M. Davies, Nick W. Albert   +8 more
wiley   +1 more source

Thiol-reactive analogues of galanthamine, codeine and morphine as potential probes to interrogate allosteric binding within nAChRs [PDF]

, 2016
Alkaloids including galanthamine (1) and codeine (2) are reported to be positive allosteric modulators of nicotinic acetylcholine receptors (nAChRs) but the binding sites responsible for this activity are not known with certainty.
Balle, Thomas, Chebib, Mary, Gallagher, Ryan, McLeod, Malcolm   +3 more
core   +1 more source

Improved evaluation method for reliable distinction of poppy (Papaver somniferum L.) cultivars

International Journal of Horticultural Science, 1999
Investigating seven Hungarian standard cultivars (i.e. 'A1’, 'Kék Gemona', '13C-2`,'Kék Duna', `Kompolti M’, `Gödi N', 'Kozmosz) it was proved that for the reliable distinction between cultivars a complex analysis is necessitated. Because of the large
J. Bernáth, J. Bakó, F. Petheő
doaj   +1 more source

Characterization of Opioid Agonist Morphine Derivatives with Emphasis on Medicinal Chemistry

ChemMedChem, Volume 20, Issue 4, February 16, 2025.
The aim of synthesizing new opioid compounds is to produce drugs that are more potent, less addictive, and have fewer side effects, such as respiratory depression and constipation. To achieve this, we evaluated the basicity, lipophilicity, and permeability of 30 opioid compounds, including 11 newly synthesized ones, to better understand the ...
Alaa Malik, Sándor Hosztafi, Anna Vincze, András Marton, Márta Kraszni, György T. Balogh, Béla Noszál, Károly Mazák   +7 more
wiley   +1 more source

Nagysebességű HPLC elválasztások kidolgozása bioaktív vegyületek meghatározására [PDF]

, 2008
8
Boros Borbála
core  

Opium use and risk of mortality from digestive diseases: A prospective cohort study

, 2013
Objectives:Opium use, particularly in low doses, is a common practice among adults in northeastern Iran. We aimed to investigate the association between opium use and subsequent mortality from disorders of the digestive tract.Methods:We used data from ...
, Abnet, Abu-Shanab, Agius, Akram Pourshams, Ali Aliasgari, Aliasgari, Amir Ali Sohrabpour, Angulo, Arash Etemadi, Atici, Behmard, Bekheet, Borzelleca, Bosshart, Christian C Abnet, Da Costa, Darke, Degenhardt, Dhalla, Dhalla, DuPont, Elham Jafari, Farhad Islami, Farin Kamangar, Fimiani, Fischer, Friesen, Ganji, Gao, Ghadirian, Ghodse, Gomes, Hewer, Hooman Khademi, Hossein Poustchi, Hosseini, Kalant, Kamangar, Khademi, Khademi, Malaveille, Maloy, Masood, Masoomi, Masoomi, Masoud Khoshnia, Masoud M Malekzadeh, Masoumi, Merat, Mohammad Bagheri, Mousavi, Nagamatsu, Nasrollahzadeh, Okie, Pacifici, Paolo Boffetta, Paul, Paul Brennan, Paul DP Pharoah, Pourshams, Pourshams, Reece, Reece, Reece, Reza Malekzadeh, Ribeiro Pinto, Sadeghi, Sadeghian, Sadeghian, Safaii, Sanford M Dawsey, Shahryar Semnani, Shakeri, Shakeri, Shakhssalim, Solomon, Sumathi, van der Laan, Wang, Wood   +80 more
core   +1 more source

WHO Expert Committee on Drug Dependence, Thirty-fourth report. [PDF]

, 2006
The WHO Expert Committee on Drug Dependence met in Geneva from 28 to 31 March 2006. Dr Howard Zucker, Assistant Director-General, Health Technology and Pharmaceuticals, and Dr Hans Hogerzeil, Director of Medicines Policy and Standards, welcomed the ...

core  

A Theory of Natural Addiction [PDF]

, 2007
Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Ainslie, Atkinson, Attila Tasnádi, Baldwin, Baron-Cohen, Becker, Becker, Bergstrom, Blass, Blass, Blass, Bodnar, Booth, Brick, Camerer, Camerer, Campbell, Carson-DeWitt, Chiara, Cohen, Colantuoni, Cooper, Cooper, Cummings, Deth, Drewnowski, Dudley, Dum, Fantino, Fehr, Foster, Gilbertson, Gillberg, Gosnell, Griffiths, Grossman, Gruber, Gul, Harrigan, Headlee, Hirshleifer, Hirshleifer, Holtzman, Jaffe, Kahneman, Kalat, Kavaliers, Kavaliers, Killian, Laibson, Laibson, Leboyer, Leboyer, Loewenstein, Martin, McKim, Mello, Mercer, Morley, Mucha, Mucha, Nelson, Nesse, Nesse, Orphanides, Orphanides, Ostrowski, Parfitt, Pert, Pomerleau, Raiten, Raven, Robson, Rogers, Rudski, Samuelson, Sanger, Savage, Schuckit, Si, Simon, Simpkins, Smith, Sozou, Spanagel, Sullivan, Sullivan, ter Riet, Terenius, Trenton G. Smith, van Ree, van Ree, van Ree, Waeltl, Weeks, Weeks, Weiss, Williams, Yamamoto, Yeomans, Yeomans, Yeomans, Zigmond   +102 more
core   +1 more source