Results 71 to 80 of about 5,021 (275)
Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2015 Morphinan alkaloids are the most powerful narcotic analgesics currently used to treat moderate to severe and chronic pain. The feasibility of morphinan synthesis in recombinant Saccharomyces cerevisiae starting from the precursor (R,S)-norlaudanosoline ...
Elena Fossati +4 more
doaj +1 more source
Pediatric poisoning management: How clinical practice can benefit from forensic approach
Journal of Forensic Sciences, Volume 69, Issue 4, Page 1501-1507, July 2024.Abstract Pediatric population represents the most vulnerable and at risk for unintentional poisoning, with children younger than 6 years old accounting for nearly half of poison exposures. Poisoning is a time‐dependent emergency. The need to reach a scientific agreement on diagnostic protocol and treatment seems to be crucial to reduce morbidity and ...
Pascale Basilicata +5 more
wiley +1 more source
Improved evaluation method for reliable distinction of poppy (Papaver somniferum L.) cultivars
International Journal of Horticultural Science, 1999 Investigating seven Hungarian standard cultivars (i.e. 'A1’, 'Kék Gemona', '13C-2`,'Kék Duna', `Kompolti M’, `Gödi N', 'Kozmosz) it was proved that for the reliable distinction between cultivars a complex analysis is necessitated. Because of the large
J. Bernáth, J. Bakó, F. Petheő
doaj +1 more source
Opium Price Shocks and Prescription Opioids in the USA*
Oxford Bulletin of Economics and Statistics, Volume 86, Issue 3, Page 449-484, June 2024.Abstract We investigate the effect of international opium price shocks on the per capita dispensation of prescription opioids in the USA. Using quarterly county‐level data for 2002q4–2016q4, three main results emerge. First, reductions in opium prices significantly increase the quantity of opioids prescribed, and more so in counties with a larger pre ...
Claudio Deiana +2 more
wiley +1 more source
Molecular diversity and phytochemical variability in the Iranian poppy (Papaver bracteatum Lindl.): A baseline for conservation and utilization in future breeding programmes [PDF]
, 2019 In the present investigation, 72 accessions of the Iranian poppy (Papaver bracteatum Lindl.) were analyzed for genetic diversity and population structure using start codon targeted polymorphism (SCoT) and inter simple sequence repeat (ISSR) markers along
Etminan, Alireza +7 more
core +1 more source
Advanced Science, Volume 11, Issue 19, May 22, 2024.Herein, a chromosome‐level genome assembly of Menispermum dauricum is presented. A novel MdCYP80G10 enzyme is identified to catalyze C2′‐C4a phenol coupling of (S)‐reticuline into sinoacutine, the enantiomer of morphinan compounds, with predictable stereospecificity.
Zhoujie An +20 more
wiley +1 more source
Transdermal Buprenorphine Patches for Postoperative Pain Control in Abdominal Surgery [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Buprenorphine is a semi-synthetic derivative of thebaine; its low concentration is sufficient to provide effective pain relief.
Santosh Kumar +7 more
doaj +1 more source
Physiological Reports, Volume 12, Issue 5, March 2024.Opium abuse was associated with high BLLs. Neither opium abuse nor high BLLs were correlated with the complexity of CAD. Abstract Opium abuse and exposure to heavy metals elevate the risk of coronary artery disease (CAD). Therefore, we aimed to determine the association between opium abuse and blood lead levels (BLLs) and the CAD complexity.
Ramin Khameneh Bagheri +5 more
wiley +1 more source
Journal of Medicinal Plants, 2019 Background: Iranin poppy (Papaver bracteatum Lindl.) belongs to Papaveraceae family which has important alkaloids such as thebain. Objective: Investigation of genetic diversity and population structure of Iranian poppy populations from Alborz Mountains ...
javad shaghaghi +2 more
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Evaluation of ultrasound effects on growth and biochemical characteristics of Iranian poppy cell cultures and thebaine production [PDF]
Zīst/shināsī-i Giyāhī-i Īrān, 2016 Low-energy ultrasound shows multiple physiological effects on plant cells and tissues, and has numerous applications in plant biotechnology, especially in elicitation of secondary metabolites production.
Ali Asghar Askari +4 more
doaj