Results 71 to 80 of about 3,781 (264)

Cell death-inducing activity of opiates in human oral tumor cell lines [PDF]

, 2001
The International Institute of Anticancer ...
Molnar, Joseph, Varga, Andreas, 古屋, 健一郎, 坂上, 宏, 本橋, 登, 森本, 雍憲, 河瀬, 雅美, 菊地, 寛高, 西川, 博文   +8 more
core  

Effective Induction of Hairy Roots in Persian Poppy (Papaver bracteatum Lindl.) Using Sonication Method

Journal of Medicinal Plants, 2018
Background: Papaver bracteatum Lindl. Commonly known as Iranian poppy is an important medicinal plant due to the presence of benzylisoquinoline alkaloids. Objective: To evaluate the hairy root culture as a novel method for thebaine production.
N Qavami, M Azizi, F Yazdian, A Qaderi, H Nemati   +4 more
doaj  

Lineage‐Specific CYP80 Expansion and Benzylisoquinoline Alkaloid Diversity in Early‐Diverging Eudicots

Advanced Science, Volume 11, Issue 19, May 22, 2024.
Herein, a chromosome‐level genome assembly of Menispermum dauricum is presented. A novel MdCYP80G10 enzyme is identified to catalyze C2′‐C4a phenol coupling of (S)‐reticuline into sinoacutine, the enantiomer of morphinan compounds, with predictable stereospecificity.
Zhoujie An, Ranran Gao, Shanshan Chen, Ya Tian, Qi Li, Lixia Tian, Wanran Zhang, Lingzhe Kong, Baojiang Zheng, Lijun Hao, Tianyi Xin, Hui Yao, Yu Wang, Wei Song, Xin Hua, Chengwei Liu, Jingyuan Song, Huahao Fan, Wei Sun, Shilin Chen, Zhichao Xu   +20 more
wiley   +1 more source

Effects of opium dependency on hypothalamic pituitary gonadal axis

, 2006
The aim of this study was to determine the effect of opium on hypothalamic pituitary gonad function. Fifty-six opium dependent (28 men and 28 women; mean age, 25±5 year) were enrolled for hypothalamic pituitary gonadal axis. The control group considered
Mansorian, A.-R., Moein, A.-A., Moradi, A., Rakhshani, M., Roosta, L., Shahramian, I., Shakeri, S.   +6 more
core   +1 more source

Synthesis, biological evaluation, and utility of fluorescent ligands targeting the μ-opioid receptor [PDF]

, 2015
Fluorescently labeled ligands are useful pharmacological research tools for studying receptor localization, trafficking, and signaling processes via fluorescence imaging. They are also employed in fluorescent binding assays. This study is centered on the
Briddon, Stephen J., Canals, Meritxell, Graham, Bim, Kellam, Barrie, Scammells, Peter J., Schembri, Luke S., Stoddart, Leigh A.   +6 more
core   +4 more sources

Evaluating the association between opium abuse, blood lead levels, and the complexity of coronary artery disease

Physiological Reports, Volume 12, Issue 5, March 2024.
Opium abuse was associated with high BLLs. Neither opium abuse nor high BLLs were correlated with the complexity of CAD. Abstract Opium abuse and exposure to heavy metals elevate the risk of coronary artery disease (CAD). Therefore, we aimed to determine the association between opium abuse and blood lead levels (BLLs) and the CAD complexity.
Ramin Khameneh Bagheri, Seyed Hadi Mousavi, Hassan Mehrad‐Majd, Mohammad Javad Jamili, Arya Nasimi Shad, Vafa Baradaran Rahimi   +5 more
wiley   +1 more source

Fast and selective HPLC-DAD method for determination of pholcodine and related substances

Macedonian Journal of Chemistry and Chemical Engineering, 2011
Quality control of pharmaceuticals requires development of fast, efficient and reliable methods for determination of active compounds as well as known and very often unknown impurities within defined concentration ranges. In this work, a simple and rapid
Ana Petkovska, Hristina Babunovska, Marina Stefova   +2 more
doaj   +1 more source

Comparison of Morphinan Alkaloids During Different Stages of Growth in the Medicinal Plant Opium Poppy (Papaver somniferum L.)

Journal of Medicinal Plants, 2012
Background: Opium poppy contains important pharmaceutical alkaloids such as Morphine, Codeine, Thebaine, Noscapine, Papaverine and Sanguinarine which are of a high economic value in pharmaceutical industries.
M Omidi, F Koohzadi, M Solouki, R Taghizad Farid, H Alizadeh   +4 more
doaj  

Alkaloid Accumulation and Distribution within the Capsules of Two Opium Poppy (Papaver somniferum L.) Varieties

Plants
The goal of this study was to clarify the role of capsule size and morphology in the alkaloid yield of poppy. In 2023, two industrial varieties from large-scale cultivation were investigated.
Péter Májer, Éva Zámboriné Németh
doaj   +1 more source

Chemometric approach for development, optimization and validation of HILIC methods used for the determination of alkaloids from poppy straw

Macedonian Journal of Chemistry and Chemical Engineering, 2014
Two hydrophilic interaction liquid chromatography (HILIC) methods for simultaneous determination of the major alkaloids (morphine, codeine, thebaine, oripavine, papaverine and noscapine) in opium poppy straw (Papaver somniferum L., Papaveraceae) were ...
Jelena Acevska, Gjoshe Stefkov, Natalija Nakov, Rumenka Petkovska, Liljana Ugrinova, Svetlana Kulevanova, Aneta Dimitrovska   +6 more
doaj   +1 more source