Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition [PDF]
Several drugs and natural compounds are known to be highly neurotoxic, triggering epileptic convulsions or seizures, and causing headaches, agitations, as well as other neuronal symptoms.
Contestabile, Roberto +9 more
core +3 more sources
This study systematically investigated 52 Fu brick tea (FBT) samples collected from seven representative regions in China. High‐through put sequencing revealed that Aspergillus, Wallemia, and Candida were the predominant fungal genera across the samples.
Lisha Ran +9 more
wiley +1 more source
Graphene Oxide: A Smart (Starting) Material for Natural Methylxanthines Adsorption and Detection
Natural methylxanthines, caffeine, theophylline and theobromine, are widespread biologically active alkaloids in human nutrition, found mainly in beverages (coffee, tea, cocoa, energy drinks, etc.). Their detection is thus of extreme importance, and many
Rita Petrucci +6 more
doaj +1 more source
Objectives: This study investigated the efficacy of theobromine in comparison with 0.05% sodium fluoride solution for remineralization of initial enamel caries lesions (IECLs).
Farnaz Farhad +3 more
doaj +1 more source
Pressurized liquid extraction of caffeine and catechins from green tea leaves using ethyl lactate, water and ethyl lactate + water mixtures [PDF]
Ethyl-lactate (ethyl 2-hydroxy-propanoate) is a bio-renewable agrochemical solvent, very suitable and environmental benign for food applications, permitted by the U.S. Food and Drug Administration as pharmaceutical and food additive.
Bermejo, David Villanueva +4 more
core +1 more source
Analysis of operating variables for Yerba mate leaves supercritical carbon dioxide extraction [PDF]
Given the increasing demand for potassium in Brazil, the mining and use of carnallite is becoming increasingly important, because the current source of potassium, sylvinite, is being depleted and there is a risk of shortages.
Teofilović Branislava +4 more
doaj +1 more source
In vitro ion chelating, antioxidative mechanism of extracts from fruits and barks of tetrapleura tetraptera and their protective effects against fenton mediated toxicity of metal ions on liver homogenates [PDF]
The aim of the present study was to investigate the antioxidant activity and protective potential of T. tetraptera extracts against ion toxicity. The antioxidant activity of the extracts was investigated spectrophotometrically against several radicals (1,
Biapa, P. C. N. +6 more
core +3 more sources
Growth environment strongly influences green coffee bean biochemistry, linking phytochemical composition to adaptation under abiotic stress. Abstract This study explores how bioactive compounds in green coffee beans (Coffea arabica L.) vary across different geographic regions, addressing the key question of how environmental factors shape coffee ...
I. Pettazzoni +6 more
wiley +1 more source
The aim of the work is thesynthesis and research of physical and chemical properties of earlier undescribed 1,8-disubstituted of theobromine, which are potential biologically active compounds.
D. G. Ivanchenko +3 more
doaj +1 more source
A Riboflavin‐Derived Flavinium Salt Mediates Chemoselective Methylation Reactions
A two‐component methylation protocol was developed, where the active flavin mediator can be recycled in a single step. Crystallographic data and NMR spectroscopy support the mechanistic proposal, while chemoselective methylation was observed for a broad range of biologically relevant substrates. ABSTRACT Selective methylation is among the most relevant
Tim Langschwager +3 more
wiley +1 more source

