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Therapeutic vaccines for herpesviruses [PDF]

The Journal of Clinical Investigation
Herpesviruses establish latent infections, and most reactivate frequently, resulting in symptoms and virus shedding in healthy individuals. In immunocompromised patients, reactivating virus can cause severe disease.
Jeffrey I. Cohen
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Cancer Vaccines: Promising Therapeutics or an Unattainable Dream

Vaccines, 2021
The advent of cancer immunotherapy has revolutionized the field of cancer treatment and offers cancer patients new hope. Although this therapy has proved highly successful for some patients, its efficacy is not all encompassing and several cancer types ...
Howard Donninger, Chi Li, John W. Eaton, Kavitha Yaddanapudi   +3 more
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Therapeutic Vaccines for Non-Communicable Diseases: Global Progress and China’s Deployment Pathways [PDF]

Vaccines
Background: Non-communicable diseases (NCDs) have become a major threat to global public health, with the disease burden particularly severe in developing countries, China being one of them.
Yifan Huang, Xiaohang Lyu, Yiu-Wing Kam
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Clinical-epidemiological characteristics and maternal-foetal outcomes in pregnant women hospitalised with COVID-19 in Venezuela: a retrospective study

BMC Pregnancy and Childbirth, 2022
Background In low- and middle-income countries, pregnant women and newborns are more vulnerable to adverse outcomes from coronavirus disease 2019 (COVID-19).
Fhabián S. Carrión-Nessi, Mercedes P. Castro, Diana C. Freitas-De Nobrega, Augusto Moncada-Ortega, Óscar D. Omaña-Ávila, Daniela L. Mendoza-Millán, María V. Marcano-Rojas, Nayren J. Trejo, Isabella V. Virriel, Melynar Chavero, Natasha A. Camejo-Ávila, Alfonso J. Rodriguez-Morales, David A. Forero-Peña   +12 more
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Seroprevalence of viral and bacterial pathogens among malaria patients in an endemic area of southern Venezuela

Infectious Diseases of Poverty, 2023
Background Malaria remains a leading public health problem worldwide. Co-infections with other pathogens complicate its diagnosis and may modify the disease’s clinical course and management.
David A. Forero-Peña, Fhabián S. Carrión-Nessi, Mary Lopez-Perez, Marisol Sandoval-de Mora, Iván D. Amaya, Ángel F. Gamardo, Melynar Chavero, Luisamy Figuera, María V. Marcano, Natasha A. Camejo-Ávila, Mariana Hidalgo, Cariagne J. Arenas, Myriam Arévalo-Herrera, Sócrates Herrera   +13 more
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ACTIV-6: Operationalizing a decentralized, outpatient randomized platform trial to evaluate efficacy of repurposed medicines for COVID-19

Journal of Clinical and Translational Science, 2023
Despite the availability of vaccinations, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to cause Coronavirus Disease 2019 (COVID-19) infection with a spectrum of disease in the acute setting.
The Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group
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The clinical–epidemiological profile of malaria patients from Southern Venezuela, a critical hotspot in Latin America

Malaria Journal, 2021
Background Venezuela accounted for 55% of the cases and 73% of the malaria deaths in the Americas in 2019. Bolivar state, in the southeast, contributes > 60% of the country's Plasmodium vivax and Plasmodium falciparum cases every year.
David A. Forero-Peña, Fhabián S. Carrión-Nessi, Melynar Chavero, Ángel Gamardo, Luisamy Figuera, Natasha A. Camejo-Ávila, María V. Marcano, Mariana Hidalgo, Cariagne J. Arenas-Leal, Leopoldo Villegas, María E. Grillet, M. Andreína Pacheco, Marisol Sandoval-de Mora, Ananías A. Escalante   +13 more
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New daily persistent headache after SARS-CoV-2 infection in Latin America: a cross-sectional study

BMC Infectious Diseases, 2023
Background Persistent headache is a frequent symptom after coronavirus disease 2019 (COVID-19) and there is currently limited knowledge about its clinical spectrum and predisposing factors.
Fhabián S. Carrión-Nessi, Luis C. Ascanio, Andreína G. Pineda-Arapé, Óscar D. Omaña-Ávila, Daniela L. Mendoza-Millán, Sinibaldo R. Romero, Abranny B. Almao-Rivero, Natasha A. Camejo-Ávila, Karim J. Gebran-Chedid, Carlis M. Rodriguez-Saavedra, Diana C. Freitas-De Nobrega, Sergio A. Castañeda, José L. Forero-Peña, Lourdes A. Delgado-Noguera, Lucianny K. Meneses-Ramírez, Juan C. Cotuá, Alfonso J. Rodriguez-Morales, David A. Forero-Peña, Alberto E. Paniz-Mondolfi   +18 more
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Plasmodium vivax and SARS-CoV-2 co-infection in Venezuelan pregnant women: a case series

Malaria Journal, 2023
Background Malaria‐endemic areas are not spared from the impact of coronavirus disease 2019 (COVID-19), leading to co-infection scenarios where overlapping symptoms impose serious diagnostic challenges. Current knowledge on Plasmodium spp.
Fhabián S. Carrión-Nessi, Daniela L. Mendoza-Millán, Óscar D. Omaña-Ávila, Sinibaldo R. Romero, Augusto Moncada-Ortega, Mary Lopez-Perez, Jaime R. Torres, Óscar Noya-González, David A. Forero-Peña   +8 more
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Knowledge, Attitudes, and Practices Regarding COVID-19 Among Healthcare Workers in Venezuela: An Online Cross-Sectional Survey

Frontiers in Public Health, 2021
Background: The deterioration of Venezuela's health system in recent years undoubtedly contributes to an increased impact of the COVID-19 pandemic. Understanding healthcare workers' (HCWs) knowledge, attitudes, and practices (KAPs) toward COVID-19 in the
Daniela Lucía Mendoza Millán, Daniela Lucía Mendoza Millán, Fhabián Stevens Carrión-Nessi, Mario Daniel Mejía Bernard, Mario Daniel Mejía Bernard, María Victoria Marcano-Rojas, Óscar Daniel Omaña Ávila, Óscar Daniel Omaña Ávila, Juan Manuel Doval Fernández, Juan Manuel Doval Fernández, Fabián Rafael Chacón Labrador, Fabián Rafael Chacón Labrador, Adriana Quintero Rodríguez, Sebastian Gasparini Vega, Adriana Tami, Adriana Tami, Andrea L. Maricuto, Viledy L. Velásquez, María Eugenia Landaeta, Manuel Figuera, Melynar Chavero, Luisamy Figuera, Natasha A. Camejo-Ávila, David A. Forero-Peña, David A. Forero-Peña   +24 more
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