Results 21 to 30 of about 1,969,671 (301)
Therapeutic Cancer Vaccines [PDF]
, 2014 Therapeutic cancer vaccines have the potential of being integrated in the therapy of numerous cancer types and stages. The wide spectrum of vaccine platforms and vaccine targets is reviewed along with the potential for development of vaccines to target cancer cell "stemness," the epithelial-to-mesenchymal transition (EMT) phenotype, and drug-resistant ...
Jeffrey, Schlom +9 more
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Nanoparticles and Antiviral Vaccines
, 2023 Viruses have threatened human lives for decades, causing both chronic and acute infections accompanied by mild to severe symptoms. During the long journey of confrontation, humans have developed intricate immune systems to combat viral infections.
Xingyu Liu +9 more
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Targeting purinergic pathway to enhance radiotherapy-induced immunogenic cancer cell death
Journal of Experimental & Clinical Cancer Research, 2022 Emerging evidence has demonstrated that radiotherapy (RT) can not only cause direct damage to cancer cells but also lead to immunogenic cell death (ICD), which involves the activation of host antitumor immune response in tumor immune microenvironment ...
Xuhui Bao, Liyi Xie
doaj +1 more source
Therapeutic vaccines in autoimmunity [PDF]
Proceedings of the National Academy of Sciences, 2004 Similarly to prophylactic vaccines whose purpose is to prevent infectious diseases, therapeutic vaccines against autoimmune diseases are based on their similarity to the putative causes of the disease. We shall describe here two such examples: a copolymer of amino acids related to myelin basic protein, in the case of multiple ...
Michael, Sela, Edna, Mozes
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Vaccination against Cancer or Infectious Agents during Checkpoint Inhibitor Therapy
Vaccines, 2021 The use of immune checkpoint inhibitors (ICI) has substantially increased the overall survival of cancer patients and has revolutionized the therapeutic situation in oncology. However, not all patients and cancer types respond to ICI, or become resistant
Tahseen H. Nasti +1 more
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Chikungunya: vaccines and therapeutics [PDF]
F1000Research, 2017 Chikungunya virus (CHIKV) has come to prominence as a global, re-emerging pathogen over the last two decades, progressing from sporadic, remote outbreaks to worldwide explosive epidemics. From contained, though considerable, outbreaks in the southern Indian Ocean, parts of South America and the Caribbean, CHIKV continues to be a significant pathogen in
Kothila Tharmarajah +2 more
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Therapeutic vaccines against IgE-mediated allergies
, 2008 Therapeutic vaccines targeting various self-molecules is an emerging field of vaccine development that is studied extensively in areas such as birth control, cancer, allergy and autoimmunity.
Lars Hellman, Hellman, Lars,
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Effectiveness and efficiency of imperfect therapeutic HSV-2 vaccines
, 2007 Efforts are currently underway to develop therapeutic vaccines for Herpes Simplex Virus type 2 (HSV-2). We use a mathematical model to predict the potential public health impact of imperfect, therapeutic HSV-2 vaccines.
Bodine, Erin N +2 more
core +1 more source
Frontiers in Immunology, 2023 HIV-specific T cells are necessary for control of HIV-1 replication but are largely insufficient for viral clearance. This is due in part to these cells’ recognition of immunodominant but variable regions of the virus, which facilitates viral escape via ...
Sandra Dross +23 more
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Rhabdoviruses as vectors for vaccines and therapeutics [PDF]
Current Opinion in Virology, 2020 Appropriate choice of vaccine vector is crucial for effective vaccine development. Rhabdoviral vectors, such as rabies virus and vesicular stomatitis virus, have been used in a variety of vaccine strategies. These viruses have small, easily manipulated genomes that can stably express foreign glycoproteins due to a well-established reverse genetics ...
Gabrielle Scher, Matthias J Schnell
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