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Medical Pharmacology and Therapeutics by Derek G. Waller and Anthony P. Sampson [PDF]

open access: yesBritish Journal of Pharmacy, 2017
A thorough and contemporaneous working knowledge of both pharmacology and therapeutics is integral to the current practice of pharmacy, and both disciplines form a significant and rudimentary part of the undergraduate curricula.
Amie Bain
doaj   +2 more sources

Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients [PDF]

open access: yesJournal for ImmunoTherapy of Cancer, 2019
Background The colorectal cancer antigen GUCY2C exhibits unique split tolerance, evoking antigen-specific CD8+, but not CD4+, T-cell responses that deliver anti-tumor immunity without autoimmunity in mice.
Adam E. Snook   +9 more
doaj   +4 more sources

TB and HIV Therapeutics: Pharmacology Research Priorities [PDF]

open access: yesAIDS Research and Treatment, 2012
An unprecedented number of investigational drugs are in the development pipeline for the treatment of tuberculosis. Among patients with tuberculosis, co-infection with HIV is common, and concurrent treatment of tuberculosis and HIV is now the standard ...
Kelly E. Dooley   +3 more
doaj   +2 more sources

Educating Medical Students on How to Prescribe Anti-Hyperglycaemic Drugs: A Practical Guide

open access: yesDiabetology, 2023
In the light of the rapidly increasing global incidence of, and therapeutic arsenal for, diabetes type 2, this brief report underscores the need for advancements in clinical pharmacology and therapeutics (CPT) education with regard to diabetes type 2. We
Erik M. Donker   +5 more
doaj   +1 more source

Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study

open access: yesJournal of Diabetes Research, 2022
Aims. This study is aimed at clarifying the relationship between visit-to-visit variability of glycated hemoglobin (HbA1c) and the risk of diabetic kidney disease (DKD) and to identifying the most useful index of visit-to-visit variability of HbA1c ...
Yunyi Yan   +15 more
doaj   +1 more source

2019 Overview [PDF]

open access: yes, 2020
The CNS Neuroscience & Therapeutics provides a medium for rapid publication of original clinical, experimental, and translational research papers, timely reviews, and reports of novel findings of therapeutic relevance to the central nervous system.
Boltze, Johannes   +8 more
core   +1 more source

Phytochemical Analysis, Acute Toxicity, as well as Antihyperglycemic and Antidiabetic Activities of Corchorus olitorius L. Leaf Extracts

open access: yesThe Scientific World Journal, 2022
Backgroundand Aim. Diabetes mellitus is a metabolic disorder that has no known cure with continuous endeavors to find a therapy for the condition. According to some studies, traditional leafy vegetables could prevent and manage diabetes by modifying the ...
Rebecca Nakaziba   +3 more
doaj   +1 more source

Time to Step Up: A Call to Action For the Clinical and Quantitative Pharmacology Community to Accelerate Therapeutics for COVID‐19

open access: yesClinical and Translational Science, 2020
The global response to finding therapeutics for coronavirus disease 2019 (COVID‐19) is chaotic even if well intentioned. There is an opportunity, but more importantly, an obligation for the global clinical and quantitative pharmacology community to come ...
Dan Hartman   +4 more
doaj   +1 more source

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

open access: yesScientific Reports, 2023
The inaccessibility of human cardiomyocytes significantly hindered years of cardiovascular research efforts. To overcome these limitations, non-human cell sources were used as proxies to study heart function and associated diseases.
Kyla Bourque   +5 more
doaj   +1 more source

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